Cytokine therapy reverses NK cell anergy in MHC-deficient tumors (Q35140125)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25329698%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

Cytokine therapy reverses NK cell anergy in MHC-deficient tumors (English)

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21 February 2020

5

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21 February 2020

Aaron Ring

8

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21 February 2020

David H. Raulet

11

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21 February 2020

author name string

Michele Ardolino

1

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21 February 2020

Camillia S Azimi

2

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21 February 2020

Alexandre Iannello

3

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21 February 2020

Troy N Trevino

4

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21 February 2020

Lily Zhang

6

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21 February 2020

Weiwen Deng

7

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21 February 2020

Suzanne Fischer

9

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21 February 2020

K Christopher Garcia

10

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21 February 2020

language of work or name

English

0 references

publication date

20 October 2014

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Journal of Clinical Investigation

21 February 2020

published in

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21 February 2020

volume

124

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21 February 2020

issue

11

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21 February 2020

page(s)

4781-4794

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NK cell self tolerance, responsiveness and missing self recognition

21 February 2020

cites work

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28 July 2018

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Intravital Imaging Reveals Distinct Dynamics for Natural Killer and CD8+ T Cells during Tumor Regression

28 July 2018

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Mature natural killer cells reset their responsiveness when exposed to an altered MHC environment

28 July 2018

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In vivo tumor cell rejection induced by NK cell inhibitory receptor blockade: maintained tolerance to normal cells even in the presence of IL-2.

28 July 2018

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Genetic and antibody-mediated reprogramming of natural killer cell missing-self recognition in vivo

28 July 2018

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Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells

28 July 2018

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NK cell responsiveness is tuned commensurate with the number of inhibitory receptors for self-MHC class I: the rheostat model

28 July 2018

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Maturation of mouse NK cells is a 4-stage developmental program.

28 July 2018

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Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1.

28 July 2018

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Cutting edge: viral infection breaks NK cell tolerance to "missing self".

28 July 2018

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Regulation of NK cell responsiveness to achieve self-tolerance and maximal responses to diseased target cells

28 July 2018

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The role of regulatory T cells in the control of natural killer cells: relevance during tumor progression

28 July 2018

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28 July 2018

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A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules

28 July 2018

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28 July 2018

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28 July 2018

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Characterization of a murine NKT cell tumor previously described as an acute myelogenous leukemia

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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MHC Class I Deficiency: Susceptibility to Natural Killer (NK) Cells and Impaired NK Activity

28 July 2018

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28 July 2018

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Major histocompatibility complex (MHC)-encoded HAM2 is necessary for antigenic peptide loading onto class I MHC molecules

28 July 2018

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28 July 2018

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27 September 2018

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Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor.

27 September 2018

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27 September 2018

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27 September 2018

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27 September 2018

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Insertion of interleukin-2 (IL-2) and interleukin-12 (IL-12) genes into vaccinia virus results in effective anti-tumor responses without toxicity

27 September 2018

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Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity

27 September 2018

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Innate and adaptive immunity to tumors: IL-12 is required for optimal responses.

27 September 2018

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LPS-stimulated SJL macrophages produce IL-12 and IL-18 that inhibit IgE production in vitro by induction of IFN-gamma production from CD3intIL-2R beta+ T cells

27 September 2018

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Observation of Antigen-Dependent CD8+ T-Cell/ Dendritic Cell Interactions in Vivo

27 September 2018

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IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production

25 October 2018

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12 December 2020

Synergistic effects of IL-12 and IL-18 in skewing tumor-reactive T-cell responses towards a type 1 pattern

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12 December 2020

Cytokine therapy in cancer

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12 December 2020

Depletion of CD4+CD25+ regulatory T cells enhances natural killer T cell-mediated anti-tumour immunity in a murine mammary breast cancer model

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A phase 1 trial of the anti-inhibitory KIR mAb IPH2101 for AML in complete remission

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Identifiers

DOI

10.1172/JCI74337

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25329698%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25329698%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

PubMed publication ID

25329698

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25329698%20AND%20SRC:MED&resulttype=core&format=json