Endosomal generation of cAMP in GPCR signaling (Q35563982)

8 August 2017

1 reference

title

Endosomal generation of cAMP in GPCR signaling (English)

1 reference

25271346

G protein-coupled receptor

8 August 2017

main subject

0 references

author

Jean-Pierre Vilardaga

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25271346%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Frédéric Jean-Alphonse

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25271346%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Thomas J Gardella

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25271346%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

publication date

1 September 2014

1 reference

25271346

8 August 2017

published in

Nature Chemical Biology

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25271346%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

10

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4 June 2020

issue

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25271346%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

700-706

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25271346%20AND%20SRC:MED&resulttype=core&format=json

Endosomal GPCR signaling turned off by negative feedback actions of PKA and v-ATPase

4 June 2020

cites work

1 reference

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12 July 2018

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Investigating signaling consequences of GPCR trafficking in the endocytic pathway

12 July 2018

1 reference

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Noncanonical control of vasopressin receptor type 2 signaling by retromer and arrestin.

12 July 2018

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Glucagon-like peptide-1 receptor-mediated endosomal cAMP generation promotes glucose-stimulated insulin secretion in pancreatic β-cells.

12 July 2018

1 reference

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Critical role of parathyroid hormone (PTH) receptor-1 phosphorylation in regulating acute responses to PTH

12 July 2018

1 reference

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Conformational biosensors reveal GPCR signalling from endosomes.

12 July 2018

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Pituitary adenylate cyclase 1 receptor internalization and endosomal signaling mediate the pituitary adenylate cyclase activating polypeptide-induced increase in guinea pig cardiac neuron excitability

12 July 2018

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Noncanonical GPCR signaling arising from a PTH receptor-arrestin-Gβγ complex

12 July 2018

1 reference

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Modulating neuromodulation by receptor membrane traffic in the endocytic pathway

12 July 2018

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Non-canonical signaling of the PTH receptor

12 July 2018

1 reference

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Fluorescence/bioluminescence resonance energy transfer techniques to study G-protein-coupled receptor activation and signaling

12 July 2018

1 reference

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Synthetic human parathyroid hormone 1-34 replacement therapy: a randomized crossover trial comparing pump versus injections in the treatment of chronic hypoparathyroidism

12 July 2018

1 reference

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Endocytosis promotes rapid dopaminergic signaling

12 July 2018

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Nanobody stabilization of G protein-coupled receptor conformational states.

12 July 2018

1 reference

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Retromer terminates the generation of cAMP by internalized PTH receptors

12 July 2018

1 reference

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The arrestin fold: variations on a theme

12 July 2018

1 reference

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Sustained cyclic AMP production by parathyroid hormone receptor endocytosis.

12 July 2018

1 reference

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Endocytosis and signalling: intertwining molecular networks

12 July 2018

1 reference

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Persistent cAMP-signals triggered by internalized G-protein-coupled receptors

12 July 2018

1 reference

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GPCR and G proteins: drug efficacy and activation in live cells.

12 July 2018

1 reference

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Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation

12 July 2018

1 reference

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Dissociation of heterotrimeric g proteins in cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417940

The structure and function of the retromer protein complex.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417940

Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors.

12 July 2018

1 reference

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Conformational cross-talk between alpha2A-adrenergic and mu-opioid receptors controls cell signaling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417940

Structure of Vps26B and mapping of its interaction with the retromer protein complex

12 July 2018

1 reference

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Functional architecture of the retromer cargo-recognition complex

12 July 2018

1 reference

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Altered selectivity of parathyroid hormone (PTH) and PTH-related protein (PTHrP) for distinct conformations of the PTH/PTHrP receptor.

12 July 2018

1 reference

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Seven transmembrane receptors: something old, something new.

12 July 2018

1 reference

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Retrograde transport from endosomes to the trans-Golgi network

12 July 2018

1 reference

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Probing the activation-promoted structural rearrangements in preassembled receptor-G protein complexes.

12 July 2018

1 reference

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The retromer subunit Vps26 has an arrestin fold and binds Vps35 through its C-terminal domain

12 July 2018

1 reference

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Molecular basis of inverse agonism in a G protein-coupled receptor

12 July 2018

1 reference

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Dynamics of receptor/G protein coupling in living cells

12 July 2018

1 reference

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Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism.

12 July 2018

1 reference

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A docking site for G protein βγ subunits on the parathyroid hormone 1 receptor supports signaling through multiple pathways

12 July 2018

1 reference

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What's for lunch at the conformational cafeteria?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417940

Real-time monitoring of receptor and G-protein interactions in living cells.

12 July 2018

1 reference

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A FlAsH-based FRET approach to determine G protein-coupled receptor activation in living cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417940

Gi protein activation in intact cells involves subunit rearrangement rather than dissociation

12 July 2018

1 reference

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Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins

12 July 2018

1 reference

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Internalization determinants of the parathyroid hormone receptor differentially regulate beta-arrestin/receptor association

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417940

Agonist-induced conformational changes in the G-protein-coupling domain of the beta 2 adrenergic receptor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417940

The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417940

Identification of phosphorylation sites in the G protein-coupled receptor for parathyroid hormone. Receptor phosphorylation is not required for agonist-induced internalization

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417940

Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor

12 July 2018

1 reference

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Overexpression of beta-arrestin and beta-adrenergic receptor kinase augment desensitization of beta 2-adrenergic receptors

12 July 2018

1 reference

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A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor

12 July 2018

1 reference

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Structural analysis of human proparathyroid hormone by a new microsequencing approach

12 July 2018

1 reference

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The N-Terminal Amino-Acid Sequence of Bovine Proparathyroid Hormone

12 July 2018

1 reference

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A parathyroid hormone-related protein implicated in malignant hypercalcemia: cloning and expression

12 July 2018

1 reference

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Light-dependent phosphorylation of rhodopsin by beta-adrenergic receptor kinase

12 July 2018

1 reference

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Parathyroid hormone-related protein purified from a human lung cancer cell line

12 July 2018

1 reference

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beta-Arrestin: a protein that regulates beta-adrenergic receptor function

12 July 2018

1 reference

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Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417940

Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417940

Measurement of the millisecond activation switch of G protein-coupled receptors in living cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417940

Functionally different agonists induce distinct conformations in the G protein coupling domain of the beta 2 adrenergic receptor

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4417940

Molecular basis of partial agonism at the neurotransmitter alpha2A-adrenergic receptor and Gi-protein heterotrimer

26 September 2018

1 reference

12 December 2020

Arrestin/clathrin interaction. Localization of the clathrin binding domain of nonvisual arrestins to the carboxy terminus

1 reference

12 December 2020

Photoactivated conformational changes in rhodopsin: a time-resolved spin label study

1 reference

12 December 2020

Kinetics and dynamics in the G protein-coupled receptor signaling cascade

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCHEMBIO.1611

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25271346%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

4 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25271346%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

25271346

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25271346%20AND%20SRC:MED&resulttype=core&format=json