Preaxial polydactyly caused by Gli3 haploinsufficiency is rescued by Zic3 loss of function in mice (Q35856281)

10 August 2017

Preaxial polydactyly caused by Gli3 haploinsufficiency is rescued by Zic3 loss of function in mice (English)

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10 August 2017

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Malgorzata E Quinn

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10 August 2017

Allison Haaning

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2

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10 August 2017

Stephanie M Ware

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3

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10 August 2017

10 January 2012

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10 August 2017

Human Molecular Genetics

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10 August 2017

21

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10 August 2017

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10 August 2017

1888-1896

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describes a project that uses

10 August 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3313802/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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11 July 2018

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Polydactyly in the mouse mutant Doublefoot involves altered Gli3 processing and is caused by a large deletion in cis to Indian hedgehog

11 July 2018

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Heart defects in X-linked heterotaxy: evidence for a genetic interaction of Zic3 with the nodal signaling pathway

11 July 2018

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11 July 2018

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Heterozygous deletion of the linked genes ZIC1 and ZIC4 is involved in Dandy-Walker malformation

11 July 2018

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Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities

11 July 2018

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Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning

11 July 2018

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Identification and functional analysis of ZIC3 mutations in heterotaxy and related congenital heart defects

11 July 2018

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Mammary gland, limb and yolk sac defects in mice lacking Tbx3, the gene mutated in human ulnar mammary syndrome

11 July 2018

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Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity

11 July 2018

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A complex syndrome of left-right axis, central nervous system and axial skeleton defects in Zic3 mutant mice

11 July 2018

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Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function

11 July 2018

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Physical and functional interactions between Zic and Gli proteins

11 July 2018

1 reference

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Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins

11 July 2018

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A new murine zinc finger gene, Opr.

11 July 2018

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Autoregulation of Shh expression and Shh induction of cell death suggest a mechanism for modulating polarising activity during chick limb development

11 July 2018

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An efficient recombination system for chromosome engineering in Escherichia coli

11 July 2018

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Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

11 July 2018

1 reference

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Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1

11 July 2018

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GLI3 mutations in human disorders mimic Drosophila cubitus interruptus protein functions and localization

11 July 2018

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Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3

11 July 2018

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Holoprosencephaly due to mutations in ZIC2, a homologue of Drosophila odd-paired

11 July 2018

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Polydactyly and ectopic ZPA formation in Alx-4 mutant mice

11 July 2018

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X-linked situs abnormalities result from mutations in ZIC3

11 July 2018

1 reference

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Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb development

11 July 2018

1 reference

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The expression of the mouse Zic1, Zic2, and Zic3 gene suggests an essential role for Zic genes in body pattern formation

11 July 2018

1 reference

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A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene

11 July 2018

1 reference

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Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development

11 July 2018

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A positive feedback loop coordinates growth and patterning in the vertebrate limb.

11 July 2018

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A novel zinc finger protein, zic, is involved in neurogenesis, especially in the cell lineage of cerebellar granule cells

11 July 2018

1 reference

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Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

11 July 2018

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The timing of ossification of the limb bones, and growth rates of various long bones of the fore and hind limbs of the prenatal and early postnatal laboratory mouse

11 July 2018

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The GLI gene encodes a nuclear protein which binds specific sequences in the human genome

11 July 2018

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GLI3 zinc-finger gene interrupted by translocations in Greig syndrome families

11 July 2018

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Chromosomal dynamics at the Shh locus: limb bud-specific differential regulation of competence and active transcription

27 July 2018

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Zic3 is critical for early embryonic patterning during gastrulation

24 September 2018

1 reference

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Gli3 and Plzf cooperate in proximal limb patterning at early stages of limb development

24 September 2018

1 reference

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Levels of Gli3 repressor correlate with Bmp4 expression and apoptosis during limb development.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313802

Direct interaction with Hoxd proteins reverses Gli3-repressor function to promote digit formation downstream of Shh.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313802

Progression of vertebrate limb development through SHH-mediated counteraction of GLI3.

24 September 2018

1 reference

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GLI3 frameshift mutations cause autosomal dominant Pallister-Hall syndrome

24 September 2018

1 reference

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Limb development in mouse embryos. I. Analysis of teratogenic effects of retinoic acid

24 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FHMG%2FDDS002

Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FHMG%2FDDS002

A duplicated zone of polarizing activity in polydactylous mouse mutants

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22234993

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/HMG/DDS002

1 reference

10 August 2017

1 reference

10 August 2017

PubMed publication ID

22234993

1 reference