MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149-5p Regulate the Expression of Proapoptotic BH3-Only Proteins DP5 and PUMA in Human Pancreatic β-Cells. (Q36163240)

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English	MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149-5p Regulate the Expression of Proapoptotic BH3-Only Proteins DP5 and PUMA in Human Pancreatic β-Cells.	scientific article

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25 March 2020

MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149-5p Regulate the Expression of Proapoptotic BH3-Only Proteins DP5 and PUMA in Human Pancreatic β-Cells (English)

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25 March 2020

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Francesco Dotta

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Laura Marroquí

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Fabio Arturo Grieco

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Guido Sebastiani

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Jonas Juan-Mateu

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Olatz Villate

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Laurence Ladrière

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Ksenya Tugay

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Piero Marchetti

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Décio L Eizirik

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13 October 2016

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25 March 2020

Viral infections in type 1 diabetes mellitus--why the β cells?

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2 July 2018

ER stress and the decline and fall of pancreatic beta cells in type 1 diabetes

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Super enhancers at the miR-146a and miR-155 genes contribute to self-regulation of inflammation

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2 July 2018

Coxsackievirus B5 Infection Induces Dysregulation of microRNAs Predicted to Target Known Type 1 Diabetes Risk Genes in Human Pancreatic Islets.

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2 July 2018

Genes affecting β-cell function in type 1 diabetes

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2 July 2018

MicroRNAs: Novel Players in the Dialogue between Pancreatic Islets and Immune System in Autoimmune Diabetes

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2 July 2018

TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic β-Cells

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2 July 2018

Differentially Expressed MicroRNA-483 Confers Distinct Functions in Pancreatic β- and α-Cells.

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2 July 2018

Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms

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2 July 2018

MicroRNAs and the functional β cell mass: For better or worse

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2 July 2018

Role of islet microRNAs in diabetes: which model for which question?

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2 July 2018

Regulation of Pancreatic Beta Cell Stimulus-Secretion Coupling by microRNAs.

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2 July 2018

Downregulation of miR-23a and miR-27a following experimental traumatic brain injury induces neuronal cell death through activation of proapoptotic Bcl-2 proteins

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2 July 2018

Downregulation of Bcl-2 expression by miR-34a mediates palmitate-induced Min6 cells apoptosis.

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2 July 2018

Pancreatic pathology in type 1 diabetes mellitus

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2 July 2018

Candidate genes for type 1 diabetes modulate pancreatic islet inflammation and β-cell apoptosis

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2 July 2018

MicroRNA expression in alpha and beta cells of human pancreatic islets

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2 July 2018

The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis

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2 July 2018

Signalling danger: endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation

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2 July 2018

MicroRNAs in pancreas development

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2 July 2018

Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis

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2 July 2018

Changes in microRNA expression contribute to pancreatic β-cell dysfunction in prediabetic NOD mice

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2 July 2018

The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines

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2 July 2018

Immunology in the clinic review series; focus on type 1 diabetes and viruses: how viral infections modulate beta cell function

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2 July 2018

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients.

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2 July 2018

Increased expression of microRNA miR-326 in type 1 diabetic patients with ongoing islet autoimmunity

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2 July 2018

Diabetogenic T lymphocytes in human Type 1 diabetes

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2 July 2018

A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion

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2 July 2018

Bcl-2 proteins in diabetes: mitochondrial pathways of β-cell death and dysfunction

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2 July 2018

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2 July 2018

p53 up-regulated modulator of apoptosis (PUMA) activation contributes to pancreatic beta-cell apoptosis induced by proinflammatory cytokines and endoplasmic reticulum stress

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2 July 2018

Involvement of microRNAs in the cytotoxic effects exerted by proinflammatory cytokines on pancreatic beta-cells.

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2 July 2018

The role of inflammation in insulitis and beta-cell loss in type 1 diabetes

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2 July 2018

PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis

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2 July 2018

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23 September 2018

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23 September 2018

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23 September 2018

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23 September 2018

MicroRNA expression profiling and functional annotation analysis of their targets in patients with type 1 diabetes mellitus

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5 December 2018

Use of RNA interference to investigate cytokine signal transduction in pancreatic beta cells

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12 December 2020

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Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR

1 reference

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12 December 2020

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Identification of novel cytokine-induced genes in pancreatic beta-cells by high-density oligonucleotide arrays

1 reference

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12 December 2020

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Signaling by IL-1beta+IFN-gamma and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic beta-cell apoptosis

1 reference

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12 December 2020

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Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies

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https://pubmed.ncbi.nlm.nih.gov/27737950

12 December 2020

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miR-101a and miR-30b contribute to inflammatory cytokine-mediated β-cell dysfunction

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https://pubmed.ncbi.nlm.nih.gov/27737950

12 December 2020

based on heuristic

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10.2337/DB16-0592

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25 March 2020

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25 March 2020

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25 March 2020

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