The molecular bases of training adaptation (Q36920587)

17 August 2017

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title

The molecular bases of training adaptation (English)

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17 August 2017

Vernon G Coffey

1

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17 August 2017

John A Hawley

series ordinal

2

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17 August 2017

publication date

1 January 2007

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17 August 2017

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17 August 2017

volume

37

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17 August 2017

issue

9

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17 August 2017

page(s)

737-763

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Sepsis and inflammatory insults downregulate IGFBP-5, but not IGFBP-4, in skeletal muscle via a TNF-dependent mechanism

17 August 2017

cites work

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12 December 2020

Critical nodes in signalling pathways: insights into insulin action

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12 December 2020

TNF-alpha acts via p38 MAPK to stimulate expression of the ubiquitin ligase atrogin1/MAFbx in skeletal muscle

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12 December 2020

Skeletal muscle Ca(2+)-independent kinase activity increases during either hypertrophy or running

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12 December 2020

Balancing muscle hypertrophy and atrophy

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12 December 2020

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

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12 December 2020

AMPK activation increases fatty acid oxidation in skeletal muscle by activating PPARalpha and PGC-1.

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12 December 2020

The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes

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12 December 2020

Insulin-like growth factor-I extends in vitro replicative life span of skeletal muscle satellite cells by enhancing G1/S cell cycle progression via the activation of phosphatidylinositol 3'-kinase/Akt signaling pathway

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12 December 2020

Coordination of metabolic plasticity in skeletal muscle

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12 December 2020

Calcineurin activation influences muscle phenotype in a muscle-specific fashion

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12 December 2020

Regulation of metabolic transcriptional co-activators and transcription factors with acute exercise.

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12 December 2020

Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins

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12 December 2020

Eukaryotic initiation factors and protein synthesis after resistance exercise in rats.

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12 December 2020

Interference of strength development by simultaneously training for strength and endurance

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12 December 2020

Progressive metabolite changes in individual human muscle fibers with increasing work rates

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12 December 2020

Calcineurin and skeletal muscle growth

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12 December 2020

Skeletal myocyte hypertrophy requires mTOR kinase activity and S6K1.

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12 December 2020

Vasopressin-dependent myogenic cell differentiation is mediated by both Ca2+/calmodulin-dependent kinase and calcineurin pathways

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12 December 2020

Insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway

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12 December 2020

Myostatin gene expression is reduced in humans with heavy-resistance strength training: a brief communication

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12 December 2020

Tumour necrosis factor-α increases the ubiquitinization of rat skeletal muscle proteins

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12 December 2020

AMPK: a key sensor of fuel and energy status in skeletal muscle

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12 December 2020

GSK-3beta negatively regulates skeletal myotube hypertrophy

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12 December 2020

Insulin and IGF-I induce pronounced hypertrophy of skeletal myofibers in tissue culture

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12 December 2020

Exercise modulates postreceptor insulin signaling and glucose transport in muscle-specific insulin receptor knockout mice

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12 December 2020

Myostatin negatively regulates satellite cell activation and self-renewal

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12 December 2020

Mitochondrial transcription factor A and respiratory complex IV increase in response to exercise training in humans

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12 December 2020

Fatiguing exercise reduces DNA binding activity of NF-kappaB in skeletal muscle nuclei

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12 December 2020

Impaired overload-induced muscle growth is associated with diminished translational signalling in aged rat fast-twitch skeletal muscle

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12 December 2020

Skeletal muscle hypertrophy and atrophy signaling pathways

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12 December 2020

Endurance training increases skeletal muscle LKB1 and PGC-1alpha protein abundance: effects of time and intensity

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12 December 2020

Effects of strength, endurance and combined training on myosin heavy chain content and fibre-type distribution in humans

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12 December 2020

Low-intensity contraction activates the alpha1-isoform of 5'-AMP-activated protein kinase in rat skeletal muscle.

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12 December 2020

Role of AMPK in skeletal muscle metabolic regulation and adaptation in relation to exercise

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12 December 2020

MEF2 responds to multiple calcium-regulated signals in the control of skeletal muscle fiber type

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12 December 2020

Exercise regulates Akt and glycogen synthase kinase-3 activities in human skeletal muscle.

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12 December 2020

Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle.

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12 December 2020

5'-AMP-activated protein kinase activity and protein expression are regulated by endurance training in human skeletal muscle

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12 December 2020

IGF-I restores satellite cell proliferative potential in immobilized old skeletal muscle

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12 December 2020

Neuromuscular and hormonal adaptations during strength and power training. A review

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12 December 2020

Intracellular signaling specificity in skeletal muscle in response to different modes of exercise

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12 December 2020

IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1.

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12 December 2020

Muscle sarcoplasmic reticulum Ca2+ cycling adaptations during 16 h of heavy intermittent cycle exercise.

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12 December 2020

Resident stem cells are not required for exercise-induced fiber-type switching and angiogenesis but are necessary for activity-dependent muscle growth.

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12 December 2020

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

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12 December 2020

Ubiquitin signalling in the NF-kappaB pathway

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12 December 2020

Adaptive response of hypertrophied skeletal muscle to endurance training.

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12 December 2020

Evidence for a mitochondrial regulatory pathway defined by peroxisome proliferator-activated receptor-gamma coactivator-1 alpha, estrogen-related receptor-alpha, and mitofusin 2

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12 December 2020

5' adenosine monophosphate-activated protein kinase, metabolism and exercise

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12 December 2020

Divergent effects of exercise on metabolic and mitogenic signaling pathways in human skeletal muscle

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12 December 2020

Transcriptional regulation of gene expression in human skeletal muscle during recovery from exercise

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12 December 2020

Exercise-induced alterations in extracellular signal-regulated kinase 1/2 and mammalian target of rapamycin (mTOR) signalling to regulatory mechanisms of mRNA translation in mouse muscle

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12 December 2020

Effect of exercise intensity on skeletal muscle AMPK signaling in humans

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12 December 2020

Effect of exercise intensity and hypoxia on skeletal muscle AMPK signaling and substrate metabolism in humans

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12 December 2020

Short-term endurance training results in a muscle-specific decrease of myostatin mRNA content in the rat

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12 December 2020

Differential transcriptional activation of select metabolic genes in response to variations in exercise intensity and duration

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12 December 2020

Sarcomere dynamics and contraction-induced injury to maximally activated single muscle fibres from soleus muscles of rats

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12 December 2020

Plasticity of skeletal muscle mitochondria: structure and function

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12 December 2020

Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells

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12 December 2020

Impact of resistance loading on myostatin expression and cell cycle regulation in young and older men and women

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12 December 2020

Evidence for 5' AMP-activated protein kinase mediation of the effect of muscle contraction on glucose transport

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12 December 2020

Efficacy of 3 days/wk resistance training on myofiber hypertrophy and myogenic mechanisms in young vs. older adults

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12 December 2020

Acute exercise activates nuclear factor (NF)-kappaB signaling pathway in rat skeletal muscle

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12 December 2020

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

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12 December 2020

Distinct roles of IkappaB proteins in regulating constitutive NF-kappaB activity.

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12 December 2020

A network of immediate early gene products propagates subtle differences in mitogen-activated protein kinase signal amplitude and duration.

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12 December 2020

Increase in S6K1 phosphorylation in human skeletal muscle following resistance exercise occurs mainly in type II muscle fibers

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12 December 2020

Insulin and exercise decrease glycogen synthase kinase-3 activity by different mechanisms in rat skeletal muscle

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12 December 2020

Metabolic and mitogenic signal transduction in human skeletal muscle after intense cycling exercise

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12 December 2020

Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway

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12 December 2020

Substrate availability and transcriptional regulation of metabolic genes in human skeletal muscle during recovery from exercise

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12 December 2020

Muscle damage impairs insulin stimulation of IRS-1, PI 3-kinase, and Akt-kinase in human skeletal muscle

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12 December 2020

Translational control mechanisms modulate skeletal muscle gene expression during hypertrophy

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12 December 2020

Calcium-regulated changes in mitochondrial phenotype in skeletal muscle cells

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12 December 2020

p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci

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12 December 2020

Regulation of the MEF2 family of transcription factors by p38

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12 December 2020

Architectural role of mitochondrial transcription factor A in maintenance of human mitochondrial DNA

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12 December 2020

Myogenin and oxidative enzyme gene expression levels are elevated in rat soleus muscles after endurance training

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12 December 2020

Resistance exercise increases muscle protein synthesis and translation of eukaryotic initiation factor 2Bepsilon mRNA in a mammalian target of rapamycin-dependent manner

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12 December 2020

Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivators

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12 December 2020

Acute treatment with TNF-alpha attenuates insulin-stimulated protein synthesis in cultures of C2C12 myotubes through a MEK1-sensitive mechanism.

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12 December 2020

Myogenic gene expression at rest and after a bout of resistance exercise in young (18-30 yr) and old (80-89 yr) women

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12 December 2020

Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise

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12 December 2020

Coactivator MBF1 preserves the redox-dependent AP-1 activity during oxidative stress in Drosophila

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12 December 2020

Akt signaling in skeletal muscle: regulation by exercise and passive stretch

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12 December 2020

Effect of exercise intensity on skeletal muscle malonyl-CoA and acetyl-CoA carboxylase

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12 December 2020

Ribosomal protein S6 phosphorylation: from protein synthesis to cell size.

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12 December 2020

Response of the ubiquitin-proteasome pathway to changes in muscle activity

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12 December 2020

Exercise rapidly increases eukaryotic elongation factor 2 phosphorylation in skeletal muscle of men

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12 December 2020

Mitofusins 1/2 and ERRalpha expression are increased in human skeletal muscle after physical exercise

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12 December 2020

Impact of aerobic exercise training on age-related changes in insulin sensitivity and muscle oxidative capacity

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12 December 2020

Muscle oxygen uptake and energy turnover during dynamic exercise at different contraction frequencies in humans

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12 December 2020

Time course of myogenic and metabolic gene expression in response to acute exercise in human skeletal muscle.

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12 December 2020

Regulation of peptide-chain elongation in mammalian cells

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12 December 2020

Localization of MyoD, myogenin and cell cycle regulatory factors in hypertrophying rat skeletal muscles

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12 December 2020

Effects of heavy resistance training on myostatin mRNA and protein expression

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12 December 2020

Effects of contractile activity on mitochondrial transcription factor A expression in skeletal muscle

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12 December 2020

Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres

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12 December 2020

Calcineurin is required for skeletal muscle hypertrophy

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12 December 2020

The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors

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12 December 2020

Regulation of muscle fiber type and running endurance by PPARdelta

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12 December 2020

Distinct signaling pathways are activated in response to mechanical stress applied axially and transversely to skeletal muscle fibers.

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12 December 2020

Proteolytic mRNA expression in response to acute resistance exercise in human single skeletal muscle fibers

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12 December 2020

Skeletal muscle hypertrophy in response to isometric, lengthening, and shortening training bouts of equivalent duration

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12 December 2020

Regulation of fatty acid oxidation and glucose metabolism in rat soleus muscle: effects of AICAR.

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12 December 2020

Redox modulation of contractile function in respiratory and limb skeletal muscle

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12 December 2020

Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner

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12 December 2020

Control of the size of the human muscle mass

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12 December 2020

Invited review: intracellular signaling in contracting skeletal muscle

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12 December 2020

Short-term exercise training in humans reduces AMPK signalling during prolonged exercise independent of muscle glycogen

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12 December 2020

AMP-activated protein kinase kinase activity and phosphorylation of AMP-activated protein kinase in contracting muscle of sedentary and endurance-trained rats.

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12 December 2020

Muscle satellite cells adopt divergent fates: a mechanism for self-renewal?

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12 December 2020

Adaptations of skeletal muscle to prolonged, intense endurance training

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12 December 2020

Effects of alpha-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle.

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12 December 2020

Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation

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12 December 2020

TNF-alpha impairs insulin signaling and insulin stimulation of glucose uptake in C2C12 muscle cells

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12 December 2020

AMPK signaling in contracting human skeletal muscle: acetyl-CoA carboxylase and NO synthase phosphorylation

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12 December 2020

Low-intensity exercise increases skeletal muscle protein expression of PPARδ and UCP3 in type 2 diabetic patients

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12 December 2020

Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.

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12 December 2020

Molecular basis of skeletal muscle plasticity--from gene to form and function

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12 December 2020

Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity

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12 December 2020

Resistance training enhances components of the insulin signaling cascade in normal and high-fat-fed rodent skeletal muscle

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12 December 2020

Ca2+-calmodulin-dependent protein kinase expression and signalling in skeletal muscle during exercise

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12 December 2020

Contraction-mediated mTOR, p70S6k, and ERK1/2 phosphorylation in aged skeletal muscle

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12 December 2020

Activation of an alternative NF-kappaB pathway in skeletal muscle during disuse atrophy

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12 December 2020

Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1alpha

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12 December 2020

5'-AMP-activated protein kinase activity and subunit expression in exercise-trained human skeletal muscle

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12 December 2020

TNF-alpha impairs heart and skeletal muscle protein synthesis by altering translation initiation

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12 December 2020

Adaptive responses of hypertrophying skeletal muscle to endurance training.

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12 December 2020

Transient overexpression of mitochondrial transcription factor A (TFAM) is sufficient to stimulate mitochondrial DNA transcription, but not sufficient to increase mtDNA copy number in cultured cells

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12 December 2020

Myostatin mutation associated with gross muscle hypertrophy in a child

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12 December 2020

Exercise induces myonuclear ubiquitination and apoptosis in dystrophin-deficient muscle of mice

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12 December 2020

Pro- and anti-inflammatory cytokine balance in strenuous exercise in humans

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12 December 2020

Inhibition of muscle insulin-like growth factor I expression by tumor necrosis factor-alpha

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12 December 2020

The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity

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12 December 2020

PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

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12 December 2020

Mechanical load increases muscle IGF-I and androgen receptor mRNA concentrations in humans

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12 December 2020

Ca2+/calmodulin-dependent phosphorylation of elongation factor 2

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12 December 2020

Senescence of human skeletal muscle impairs the local inflammatory cytokine response to acute eccentric exercise

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12 December 2020

Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation

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12 December 2020

Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions

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12 December 2020

Exercise and insulin cause GLUT-4 translocation in human skeletal muscle

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12 December 2020

Genetic loss of calcineurin blocks mechanical overload-induced skeletal muscle fiber type switching but not hypertrophy

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12 December 2020

Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle

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12 December 2020

Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2

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12 December 2020

Stimulation of slow skeletal muscle fiber gene expression by calcineurin in vivo

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12 December 2020

Skeletal muscle fiber type: influence on contractile and metabolic properties

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12 December 2020

Time course of changes in markers of myogenesis in overloaded rat skeletal muscles

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12 December 2020

Regulation of cap-dependent translation by eIF4E inhibitory proteins

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12 December 2020

mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF.

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12 December 2020

A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type

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12 December 2020

Akt signalling through GSK-3beta, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy

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12 December 2020

Intracellular signaling during skeletal muscle atrophy

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12 December 2020

Powerful genes--myostatin regulation of human muscle mass

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12 December 2020

Maximal strength and power, muscle mass, endurance and serum hormones in weightlifters and road cyclists

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12 December 2020

Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning

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12 December 2020

Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR.

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12 December 2020

Insulin and IGF-I stimulate the formation of the eukaryotic initiation factor 4F complex and protein synthesis in C2C12 myotubes independent of availability of external amino acids

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12 December 2020

Inhibition of stretch-activated channels during eccentric muscle contraction attenuates p70S6K activation

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12 December 2020

Intracellular signaling specificity in response to uniaxial vs. multiaxial stretch: implications for mechanotransduction

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12 December 2020

IGF-I stimulates protein synthesis in skeletal muscle through multiple signaling pathways during sepsis

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12 December 2020

Double muscling in cattle due to mutations in the myostatin gene

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12 December 2020

Peroxisome proliferator-activated receptor (PPAR) gamma coactivator-1 recruitment regulates PPAR subtype specificity

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12 December 2020

Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways.

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12 December 2020

Insulin-like growth factor I-mediated skeletal muscle hypertrophy is characterized by increased mTOR-p70S6K signaling without increased Akt phosphorylation

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12 December 2020

Structure of S6 kinase 1 determines whether raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site

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12 December 2020

Lower skeletal muscle mass in male transgenic mice with muscle-specific overexpression of myostatin

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12 December 2020

TNF-alpha increases ubiquitin-conjugating activity in skeletal muscle by up-regulating UbcH2/E220k

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12 December 2020

Plasticity of skeletal muscle mitochondria in response to contractile activity

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12 December 2020

Regulation of Egr-1, SRF, and Sp1 mRNA expression in contracting skeletal muscle cells

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12 December 2020

Maximal lengthening contractions increase p70 S6 kinase phosphorylation in human skeletal muscle in the absence of nutritional supply.

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12 December 2020

Identification of ubiquitin ligases required for skeletal muscle atrophy

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12 December 2020

Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion

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12 December 2020

Transcriptional activators and coactivators in the nuclear control of mitochondrial function in mammalian cells

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12 December 2020

Invited Review: contractile activity-induced mitochondrial biogenesis in skeletal muscle

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12 December 2020

NF-kappaB mediates proteolysis-inducing factor induced protein degradation and expression of the ubiquitin-proteasome system in skeletal muscle

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12 December 2020

Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity

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12 December 2020

Role of Ca2+/calmodulin-dependent kinases in skeletal muscle plasticity

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12 December 2020

Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy

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12 December 2020

The molecular basis of skeletal muscle atrophy

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12 December 2020

Nature vs. nurture: can exercise really alter fiber type composition in human skeletal muscle?

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12 December 2020

Effects of aerobic exercise training on the protein kinase B (PKB)/mammalian target of rapamycin (mTOR) signaling pathway in aged skeletal muscle

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12 December 2020

Differential activation of mTOR signaling by contractile activity in skeletal muscle

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12 December 2020

Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression

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12 December 2020

Mixed muscle protein synthesis and breakdown after resistance exercise in humans

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12 December 2020

Expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exercise.

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12 December 2020

PGC-1alpha gene expression is down-regulated by Akt- mediated phosphorylation and nuclear exclusion of FoxO1 in insulin-stimulated skeletal muscle

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12 December 2020

Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle

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12 December 2020

Concurrent strength and endurance training. A review

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12 December 2020

Time course of molecular responses of human skeletal muscle to acute bouts of resistance exercise.

1 reference

12 December 2020

IGF-1 induces human myotube hypertrophy by increasing cell recruitment

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12 December 2020

Branched-chain amino acids increase p70S6k phosphorylation in human skeletal muscle after resistance exercise

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12 December 2020

Efficacy of myonuclear addition may explain differential myofiber growth among resistance-trained young and older men and women

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12 December 2020

Injury to skeletal muscle fibers of mice following lengthening contractions

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12 December 2020

IKKbeta/NF-kappaB activation causes severe muscle wasting in mice

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12 December 2020

GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR

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12 December 2020

AMP-activated protein kinase activity and glucose uptake in rat skeletal muscle

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12 December 2020

Physiological consequences of the biochemical adaptations to endurance exercise

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12 December 2020

Conditional activation of akt in adult skeletal muscle induces rapid hypertrophy

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12 December 2020

Growing roles for the mTOR pathway

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12 December 2020

Signaling pathways in activity-dependent fiber type plasticity in adult skeletal muscle

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12 December 2020

Aging does not alter the mechanosensitivity of the p38, p70S6k, and JNK2 signaling pathways in skeletal muscle

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12 December 2020

Contractile activity-induced transcriptional activation of cytochrome C involves Sp1 and is proportional to mitochondrial ATP synthesis in C2C12 muscle cells

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12 December 2020

Acute molecular responses of skeletal muscle to resistance exercise in able-bodied and spinal cord-injured subjects

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12 December 2020

Regulation and co-ordination of nuclear gene expression during mitochondrial biogenesis

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12 December 2020

Ubiquitin, TAK1 and IKK: is there a connection?

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12 December 2020

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

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12 December 2020

Different mechanisms of increased proteolysis in atrophy induced by denervation or unweighting of rat soleus muscle

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12 December 2020

α2 isoform-specific activation of 5'adenosine monophosphate-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-β-D-ribonucleoside at a physiological level activates glucose transport and increases glucose transporter 4 in mouse skeletal mu

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12 December 2020

Interaction of contractile activity and training history on mRNA abundance in skeletal muscle from trained athletes

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12 December 2020

Localized infusion of IGF-I results in skeletal muscle hypertrophy in rats

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12 December 2020

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

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12 December 2020

Molecular determinants of skeletal muscle mass: getting the "AKT" together

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12 December 2020

Changes in human muscle protein synthesis after resistance exercise

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12 December 2020

Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase

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12 December 2020

Glucocorticoid receptor and ubiquitin expression after repeated eccentric exercise

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12 December 2020

Effects of high-intensity intermittent swimming on PGC-1alpha protein expression in rat skeletal muscle

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12 December 2020

Gene expression of myogenic factors and phenotype-specific markers in electrically stimulated muscle of paraplegics

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12 December 2020

Rheb fills a GAP between TSC and TOR.

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12 December 2020

Tumor necrosis factor-alpha inhibits myogenic differentiation through MyoD protein destabilization

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12 December 2020

Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis

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12 December 2020

Intensified exercise training does not alter AMPK signaling in human skeletal muscle

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12 December 2020

Myostatin inhibits myoblast differentiation by down-regulating MyoD expression.

1 reference

12 December 2020

A novel mTOR-regulated phosphorylation site in elongation factor 2 kinase modulates the activity of the kinase and its binding to calmodulin

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12 December 2020

Degradation of MyoD mediated by the SCF (MAFbx) ubiquitin ligase

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12 December 2020

Exercise increases Ca2+-calmodulin-dependent protein kinase II activity in human skeletal muscle

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12 December 2020

Regulation of myostatin activity and muscle growth

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12 December 2020

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

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12 December 2020

Phosphorylation of p70(S6k) correlates with increased skeletal muscle mass following resistance exercise

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12 December 2020

Control of mitochondrial morphology by a human mitofusin

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12 December 2020

Nuclear control of respiratory gene expression in mammalian cells

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12 December 2020

mTOR function in skeletal muscle hypertrophy: increased ribosomal RNA via cell cycle regulators

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12 December 2020

Muscle regeneration in the prolonged absence of myostatin

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12 December 2020

Exercise training increases lipid metabolism gene expression in human skeletal muscle

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12 December 2020

Molecular mechanisms modulating muscle mass

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12 December 2020

Regulation of mitochondrial biogenesis in muscle by endurance exercise

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12 December 2020

AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling

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12 December 2020

Matching of calcineurin activity to upstream effectors is critical for skeletal muscle fiber growth

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12 December 2020

5'AMP activated protein kinase expression in human skeletal muscle: effects of strength training and type 2 diabetes.

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12 December 2020

Muscle strength response to strength training is influenced by insulin-like growth factor 1 genotype in older adults

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12 December 2020

Regulation of mitochondrial biogenesis in skeletal muscle by CaMK

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12 December 2020

Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors

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12 December 2020

Regulation of skeletal muscle fat oxidation during exercise in humans

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12 December 2020

Effect of flywheel-based resistance exercise on processes contributing to muscle atrophy during unloading in adult rats

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12 December 2020

Altered sarcoplasmic reticulum function in rat diaphragm after high-intensity exercise

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12 December 2020

Selected contribution: acute cellular and molecular responses to resistance exercise

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12 December 2020

Immediate response of mammalian target of rapamycin (mTOR)-mediated signalling following acute resistance exercise in rat skeletal muscle

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12 December 2020

Tumour necrosis factor-alpha depletes histone deacetylase 1 protein through IKK2.

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12 December 2020

Selective activation of AMPK-PGC-1alpha or PKB-TSC2-mTOR signaling can explain specific adaptive responses to endurance or resistance training-like electrical muscle stimulation

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12 December 2020

Exercise does not alter subcellular localization, but increases phosphorylation of insulin-signaling proteins in human skeletal muscle

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12 December 2020

Effects of one bout of endurance exercise on the expression of myogenin in human quadriceps muscle

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12 December 2020

Mechanical stress activates the nuclear factor-kappaB pathway in skeletal muscle fibers: a possible role in Duchenne muscular dystrophy.

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12 December 2020

Atrophy of S6K1(-/-) skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control.

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12 December 2020

Integration of metabolic and mitogenic signal transduction in skeletal muscle.

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12 December 2020

Increased phosphorylation of Akt substrate of 160 kDa (AS160) in rat skeletal muscle in response to insulin or contractile activity

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12 December 2020

Effects of endurance training on activity and expression of AMP-activated protein kinase isoforms in rat muscles.

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12 December 2020

Mechanotransduction: all signals point to cytoskeleton, matrix, and integrins

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12 December 2020

Control of Ser2448 phosphorylation in the mammalian target of rapamycin by insulin and skeletal muscle load

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12 December 2020

Reduced skeletal muscle inhibitor of kappaB beta content is associated with insulin resistance in subjects with type 2 diabetes: reversal by exercise training

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12 December 2020

Early signaling responses to divergent exercise stimuli in skeletal muscle from well-trained humans

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12 December 2020

Cellular adaptation to repeated eccentric exercise-induced muscle damage

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12 December 2020

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

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12 December 2020

Regulation of IkappaB kinase and NF-kappaB in contracting adult rat skeletal muscle

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12 December 2020

Oxidant activity in skeletal muscle fibers is influenced by temperature, CO2 level, and muscle-derived nitric oxide.

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12 December 2020

Influence of muscle glycogen availability on ERK1/2 and Akt signaling after resistance exercise in human skeletal muscle

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12 December 2020

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

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12 December 2020

ATP and heat production in human skeletal muscle during dynamic exercise: higher efficiency of anaerobic than aerobic ATP resynthesis.

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12 December 2020

PGC-1alpha mRNA expression is influenced by metabolic perturbation in exercising human skeletal muscle.

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12 December 2020

Peroxisome proliferator-activated receptor delta controls muscle development and oxidative capability

1 reference

12 December 2020

Disuse atrophy and exercise rehabilitation in humans profoundly affects the expression of genes associated with the regulation of skeletal muscle mass.

1 reference

12 December 2020

Resistance exercise alters MRF and IGF-I mRNA content in human skeletal muscle

1 reference

12 December 2020

Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy

1 reference

12 December 2020

Skeletal muscle IGF-binding protein-3 and -5 expressions are age, muscle, and load dependent

1 reference

12 December 2020

Effects of prolonged exercise and recovery on sarcoplasmic reticulum Ca2+ cycling properties in rat muscle homogenates

1 reference

12 December 2020

Calcineurin is a potent regulator for skeletal muscle regeneration by association with NFATc1 and GATA-2

1 reference

12 December 2020

Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1.

1 reference

12 December 2020

Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

1 reference

12 December 2020

10.2165/00007256-200737090-00001

Identifiers

DOI

1 reference

Dimensions Publication ID

17 August 2017

1034117732

0 references

1 reference