Extracellular miRNA-21 as a novel biomarker in glioma: Evidence from meta-analysis, clinical validation and experimental investigations (Q37376183)

20 August 2017

1 reference

14 November 2020

1 reference

PubMed publication ID

27166186

validation studies

1 reference

PubMed publication ID

27166186

title

Extracellular miRNA-21 as a novel biomarker in glioma: Evidence from meta-analysis, clinical validation and experimental investigations (English)

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20 August 2017

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14 November 2020

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14 November 2020

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7 August 2019

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14 November 2020

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1 reference

3

Qing Pang

1 reference

20 August 2017

6

Minghui Tai

1 reference

20 August 2017

Kai Qu

1

1 reference

20 August 2017

Ting Lin

2

1 reference

20 August 2017

Tian Liu

4

1 reference

20 August 2017

Zhixin Wang

5

1 reference

20 August 2017

Fandi Meng

7

1 reference

20 August 2017

Jingyao Zhang

8

1 reference

20 August 2017

Yong Wan

9

1 reference

20 August 2017

Ping Mao

10

1 reference

20 August 2017

Xiaoqun Dong

11

1 reference

20 August 2017

Chang Liu

12

1 reference

20 August 2017

Wenquan Niu

13

1 reference

20 August 2017

Shunbin Dong

14

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20 August 2017

language of work or name

English

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publication date

5 May 2016

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20 August 2017

7 June 2016

5 references

3 April 2019

25 April 2019

19 June 2019

7 August 2019

14 November 2020

6 references

20 August 2017

3 April 2019

25 April 2019

19 June 2019

7 August 2019

14 November 2020

7

1 reference

20 August 2017

23

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20 August 2017

33994-34010

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Creative Commons Attribution 2.5 Generic

20 August 2017

5 references

3 April 2019

25 April 2019

19 June 2019

7 August 2019

on focus list of Wikimedia project

14 November 2020

ScienceSource

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cites work

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Potential Role of Circulating microRNA-21 for Hepatocellular Carcinoma Diagnosis: A Meta-Analysis

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Circulating MicroRNA-21 Is a Potential Diagnostic Biomarker in Gastric Cancer

6 September 2017

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Effects of TGF-beta signalling inhibition with galunisertib (LY2157299) in hepatocellular carcinoma models and in ex vivo whole tumor tissue samples from patients.

6 September 2017

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6 September 2017

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Circulating miR-483-3p and miR-21 is highly expressed in plasma of pancreatic cancer

6 September 2017

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Diagnostic and prognostic value of microRNA-21 in colorectal cancer: an original study and individual participant data meta-analysis.

6 September 2017

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MicroRNA-21 promotes glioblastoma tumorigenesis by down-regulating insulin-like growth factor-binding protein-3 (IGFBP3).

6 September 2017

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6 September 2017

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Serum microRNA-21 as a diagnostic marker for lung carcinoma: a systematic review and meta-analysis

6 September 2017

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Plasma microRNA-320, microRNA-let-7e and microRNA-21 as novel potential biomarkers for the detection of retinoblastoma

6 September 2017

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Circulating exosomal microRNAs as biomarkers of colon cancer.

6 September 2017

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Circulating miR-378 in plasma: a reliable, haemolysis-independent biomarker for colorectal cancer

6 September 2017

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Clinical significance of serum miR-21 in breast cancer compared with CA153 and CEA

6 September 2017

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Identification of circulating microRNAs as novel potential biomarkers for gastric cancer detection: a systematic review and meta-analysis

6 September 2017

1 reference

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MicroRNA-21 expression is associated with overall survival in patients with glioma

6 September 2017

1 reference

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Analysis of MicroRNAs in sputum to improve computed tomography for lung cancer diagnosis

6 September 2017

1 reference

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Quantification of Plasma miRNAs by Digital PCR for Cancer Diagnosis

6 September 2017

1 reference

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Plasma microRNA are disease response biomarkers in classical Hodgkin lymphoma.

6 September 2017

1 reference

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MiR-21 in the extracellular vesicles (EVs) of cerebrospinal fluid (CSF): a platform for glioblastoma biomarker development

6 September 2017

1 reference

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Diagnostic and prognostic value of circulating miR-21 for cancer: a systematic review and meta-analysis

6 September 2017

1 reference

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Diagnostic and prognostic value of plasma microRNA deregulation in nasopharyngeal carcinoma

6 September 2017

1 reference

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Analysis of serum exosomal microRNAs and clinicopathologic features of patients with pancreatic adenocarcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Involvement of FOS-mediated miR-181b/miR-21 signalling in the progression of malignant gliomas

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Serum miR-21 as a diagnostic and prognostic biomarker in colorectal cancer.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Identification and evaluation of plasma microRNAs for early detection of colorectal cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Salivary microRNAs as promising biomarkers for detection of esophageal cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Reduction of Plasma MicroRNA-21 is Associated with Chemotherapeutic Response in Patients with Non-small Cell Lung Cancer

6 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Serum circulating microRNA profiling for identification of potential breast cancer biomarkers

6 September 2017

1 reference

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Circulating microRNAs as specific biomarkers for breast cancer detection.

6 September 2017

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Smad7 suppresses renal fibrosis via altering expression of TGF-β/Smad3-regulated microRNAs

6 September 2017

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Circulating microRNA-92a and microRNA-21 as novel minimally invasive biomarkers for primary breast cancer

6 September 2017

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Detection of lung cancer with blood microRNA-21 expression levels in Chinese population

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Plasma microRNAs, miR-223, miR-21 and miR-218, as novel potential biomarkers for gastric cancer detection

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

MicroRNAs in cerebrospinal fluid identify glioblastoma and metastatic brain cancers and reflect disease activity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Circulating miR-15b and miR-130b in serum as potential markers for detecting hepatocellular carcinoma: a retrospective cohort study

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Ursolic acid inhibits proliferation and induces apoptosis in human glioblastoma cell lines U251 by suppressing TGF-β1/miR-21/PDCD4 pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

TGF-β-induced miR-21 negatively regulates the antiproliferative activity but has no effect on EMT of TGF-β in HaCaT cells.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Identification of microRNAs in the cerebrospinal fluid as biomarker for the diagnosis of glioma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

MicroRNA-21: a ubiquitously expressed pro-survival factor in cancer and other diseases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Elevated microRNA miR-21 levels in pancreatic cyst fluid are predictive of mucinous precursor lesions of ductal adenocarcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Circulating microRNAs in plasma of patients with oesophageal squamous cell carcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Characterization of extracellular circulating microRNA

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Identification of microRNAs in the cerebrospinal fluid as marker for primary diffuse large B-cell lymphoma of the central nervous system

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Plasma microRNAs as potential biomarkers for non-small-cell lung cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Origins and Mechanisms of miRNAs and siRNAs

6 September 2017

1 reference

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miR-21 and 221 upregulation and miR-181b downregulation in human grade II-IV astrocytic tumors

6 September 2017

1 reference

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Circulating microRNAs as stable blood-based markers for cancer detection

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

TGFBIp/betaig-h3 protein: a versatile matrix molecule induced by TGF-beta

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

miR-21-mediated tumor growth

6 September 2017

1 reference

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MicroRNA signatures in human cancers

6 September 2017

1 reference

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MicroRNAs: genomics, biogenesis, mechanism, and function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Circulating miRNAs 21 and 221 as biomarkers for early diagnosis of prostate cancer.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Circulating microRNAs in plasma of patients with gastric cancers

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

MicroRNAs in plasma of pancreatic ductal adenocarcinoma patients as novel blood-based biomarkers of disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Prognostic value of circulating microRNA-21 in digestive system cancers: a meta-analysis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Serum microRNAs: A new diagnostic method for colorectal cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Differential microRNAs expression in serum of patients with lung cancer, pulmonary tuberculosis, and pneumonia.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Clinical potential role of circulating microRNAs in early diagnosis of colorectal cancer patients.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Elevated level of microRNA-21 in the serum of patients with colorectal cancer.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Combined detection of serum exosomal miR-21 and HOTAIR as diagnostic and prognostic biomarkers for laryngeal squamous cell carcinoma

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

[Diagnostic values of salivary versus and plasma microRNA-21 for early esophageal cancer].

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

SurvMicro: assessment of miRNA-based prognostic signatures for cancer clinical outcomes by multivariate survival analysis

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Circulating microRNAs and kallikreins before and after radical prostatectomy: are they really prostate cancer markers?

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Plasma miR-21 is a novel diagnostic biomarker for biliary tract cancer.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Serum miR-21 is a diagnostic and prognostic marker of primary central nervous system lymphoma

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Serum miR-21 and miR-92a as biomarkers in the diagnosis and prognosis of colorectal cancer.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Identification of plasma microRNAs as novel noninvasive biomarkers for early detection of lung cancer

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Gastric juice MicroRNAs as potential biomarkers for the screening of gastric cancer.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

A three-plasma miRNA signature serves as novel biomarkers for osteosarcoma

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

MiR-21 expression in the tumor cell compartment holds unfavorable prognostic value in gliomas.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Circulating miRNA is a novel marker for head and neck squamous cell carcinoma.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

The expression and clinical significance of circulating microRNA-21 in serum of five solid tumors

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Direct serum assay for microRNA-21 concentrations in early and advanced breast cancer

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5085133

Negative regulation of transcription factor FoxM1 by p53 enhances oxaliplatin-induced senescence in hepatocellular carcinoma

2 September 2018

1 reference

12 December 2020

Plasma and EBC microRNAs as early biomarkers of non-small-cell lung cancer

1 reference

12 December 2020

The clinical utility of microRNA-21 as novel biomarker for diagnosing human cancers

1 reference

12 December 2020

MicroRNA expression analyses in preoperative pancreatic juice samples of pancreatic ductal adenocarcinoma

1 reference

12 December 2020

Prognostic role of circulating microRNA-21 in cancers: evidence from a meta-analysis

1 reference

12 December 2020

Evaluation of dynamic change of serum miR-21 and miR-24 in pre- and post-operative lung carcinoma patients

1 reference

12 December 2020

Overexpression of circulating miRNA-21 and miRNA-146a in plasma samples of breast cancer patients

1 reference

12 December 2020

MicroRNA-21 is a new marker of circulating tumor cells in gastric cancer patients

1 reference

12 December 2020

High miR-21 expression in breast cancer associated with poor disease-free survival in early stage disease and high TGF-beta1

1 reference

12 December 2020

miR-21 microRNA expression in human gastric carcinomas and its clinical association

1 reference

12 December 2020

Plasma miR-21: a potential diagnostic marker of colorectal cancer

1 reference

12 December 2020

Circulating microRNA-21 as a novel biomarker for hepatocellular carcinoma

1 reference

12 December 2020

Circulating microRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis

1 reference

12 December 2020

Identifiers

DOI

10.18632/ONCOTARGET.9188

1 reference

20 August 2017

1 reference

20 August 2017

PubMed publication ID

27166186

1 reference