Proteomic and other analyses to determine the functional consequences of deregulated kallikrein-related peptidase (KLK) expression in prostate and ovarian cancer (Q38188878)

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scientific article published on 11 May 2014

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English	Proteomic and other analyses to determine the functional consequences of deregulated kallikrein-related peptidase (KLK) expression in prostate and ovarian cancer	scientific article published on 11 May 2014

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

Proteomic and other analyses to determine the functional consequences of deregulated kallikrein-related peptidase (KLK) expression in prostate and ovarian cancer (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

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Marcus L Hastie

object named as

Marcus Lachlan Hastie

6

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Daniela Loessner

object named as

Daniela Loessner

7

0 references

Judith Clements

object named as

Judith Ann Clements

9

0 references

author name string

Ruth Anna Fuhrman-Luck

1

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

Munasinghage Lakmali Silva

2

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

Ying Dong

3

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

Helen Irving-Rodgers

4

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

Thomas Stoll

5

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

Jeffrey John Gorman

8

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Europe PubMed Central

PubMed publication ID

30 August 2017

publication date

11 May 2014

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Europe PubMed Central

PubMed publication ID

30 August 2017

Proteomics - Clinical Applications

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Europe PubMed Central

PubMed publication ID

30 August 2017

8

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Europe PubMed Central

PubMed publication ID

30 August 2017

5-6

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

403-415

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

The emerging roles of human tissue kallikreins in cancer

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential functions

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Distribution of 15 human kallikreins in tissues and biological fluids

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Tissue-specific expression patterns and fine mapping of the human kallikrein (KLK) locus on proximal 19q13.4

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Identification and characterization of KLK14, a novel kallikrein serine protease gene located on human chromosome 19q13.4 and expressed in prostate and skeletal muscle.

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Genomic organization of the human kallikrein gene family on chromosome 19q13.3-q13.4.

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Kallikreins on steroids: structure, function, and hormonal regulation of prostate-specific antigen and the extended kallikrein locus

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Activation profiles and regulatory cascades of the human kallikrein-related peptidases.

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Activation profiles of human kallikrein-related peptidases by matrix metalloproteinases

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Characterization of hK4 (prostase), a prostate-specific serine protease: activation of the precursor of prostate specific antigen (pro-PSA) and single-chain urokinase-type plasminogen activator and degradation of prostatic acid phosphatase

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Activation profiles of human kallikrein-related peptidases by proteases of the thrombostasis axis

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Interdependence of kallikrein-related peptidases in proteolytic networks

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Structures and specificity of the human kallikrein-related peptidases KLK 4, 5, 6, and 7.

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Evolution of kallikrein-related peptidases in mammals and identification of a genetic locus encoding potential regulatory inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4.

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

What can the structures of enzyme-inhibitor complexes tell us about the structures of enzyme substrate complexes?

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs).

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Natural and engineered kallikrein inhibitors: an emerging pharmacopoeia

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Prostate-cancer mortality at 11 years of follow-up

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Does PSA play a role as a promoting agent during the initiation and/or progression of prostate cancer?

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Metastatic patterns of prostate cancer: an autopsy study of 1,589 patients

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Prostate-specific kallikrein-related peptidases and their relation to prostate cancer biology and detection. Established relevance and emerging roles

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Cancer statistics, 2012

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

The biology of ovarian cancer: new opportunities for translation

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Reactivity of a monoclonal antibody with human ovarian carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

The use of multiple novel tumor biomarkers for the detection of ovarian carcinoma in patients with a pelvic mass.

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Combining multiple serum tumor markers improves detection of stage I epithelial ovarian cancer

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Kallikrein-related peptidase 7 promotes multicellular aggregation via the alpha(5)beta(1) integrin pathway and paclitaxel chemoresistance in serous epithelial ovarian carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Proteomic global profiling for cancer biomarker discovery.

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Advances in proteomic prostate cancer biomarker discovery

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Proteomics in prostate cancer biomarker discovery

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Integrating high-throughput technologies in the quest for effective biomarkers for ovarian cancer

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

In-depth proteomics to define the cell surface and secretome of ovarian cancer cells and processes of protein shedding

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Large-scale and high-confidence proteomic analysis of human seminal plasma

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Identification of differentially expressed proteins in direct expressed prostatic secretions of men with organ-confined versus extracapsular prostate cancer

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Identification of prostate-enriched proteins by in-depth proteomic analyses of expressed prostatic secretions in urine

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

The human urinary proteome contains more than 1500 proteins, including a large proportion of membrane proteins

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Characterization of the human urinary proteome: a method for high-resolution display of urinary proteins on two-dimensional electrophoresis gels with a yield of nearly 1400 distinct protein spots

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Human urine proteome analysis by three separation approaches

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Mapping the human plasma proteome by SCX-LC-IMS-MS

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Integrative proteomic analysis of serum and peritoneal fluids helps identify proteins that are up-regulated in serum of women with ovarian cancer

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Proteomic analysis of ovarian cancer cells reveals dynamic processes of protein secretion and shedding of extra-cellular domains

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Analysis of serum total and free PSA using immunoaffinity depletion coupled to SRM: correlation with clinical immunoassay tests

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Antibody-free, targeted mass-spectrometric approach for quantification of proteins at low picogram per milliliter levels in human plasma/serum

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Search for potential markers for prostate cancer diagnosis, prognosis and treatment in clinical tissue specimens using amine-specific isobaric tagging (iTRAQ) with two-dimensional liquid chromatography and tandem mass spectrometry

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Quantification of human kallikrein-2 in clinical samples by selected reaction monitoring

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Simultaneous analysis of glycosylated and sialylated prostate-specific antigen revealing differential distribution of glycosylated prostate-specific antigen isoforms in prostate cancer tissues

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Differential N-glycosylation of kallikrein 6 derived from ovarian cancer cells or the central nervous system

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Molecular microheterogeneity of prostate specific antigen in seminal fluid by mass spectrometry

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Comprehensive analysis of conditioned media from ovarian cancer cell lines identifies novel candidate markers of epithelial ovarian cancer

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

In-depth proteomics of ovarian cancer ascites: combining shotgun proteomics and selected reaction monitoring mass spectrometry.

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

PSA enzymatic activity: a new biomarker for assessing prostate cancer aggressiveness

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Functional protease profiling for diagnosis of malignant disease

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Defining the extended substrate specificity of kallikrein 1-related peptidases

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Substrates of the prostate-specific serine protease prostase/KLK4 defined by positional-scanning peptide libraries

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Substrate specificity of human kallikrein 2 (hK2) as determined by phage display technology

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Enzymatic profiling of human kallikrein 14 using phage-display substrate technology

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Characterization of the prime and non-prime active site specificities of proteases by proteome-derived peptide libraries and tandem mass spectrometry.

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Expression and functional characterization of the cancer-related serine protease, human tissue kallikrein 14

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Human kallikrein 13 involvement in extracellular matrix degradation

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21 January 2018

Biochemical and enzymatic characterization of human kallikrein 5 (hK5), a novel serine protease potentially involved in cancer progression

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Response of human peritoneal mesothelial cells to inflammatory injury is regulated by interleukin-1beta and tumor necrosis factor-alpha.

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Kallikrein 7 enhances pancreatic cancer cell invasion by shedding E-cadherin

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

Engagement of collagen-binding integrins promotes matrix metalloproteinase-9-dependent E-cadherin ectodomain shedding in ovarian carcinoma cells

1 reference

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21 January 2018

Integrin alphaVbeta6-mediated activation of latent TGF-beta requires the latent TGF-beta binding protein-1.

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21 January 2018

Transforming growth factor-beta 1 modulates beta 1 and beta 5 integrin receptors and induces the de novo expression of the alpha v beta 6 heterodimer in normal human keratinocytes: implications for wound healing.

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21 January 2018

Identifying and quantifying proteolytic events and the natural N terminome by terminal amine isotopic labeling of substrates

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21 January 2018

Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin

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21 January 2018

Mineralized human primary osteoblast matrices as a model system to analyse interactions of prostate cancer cells with the bone microenvironment

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21 January 2018

Hypomaturation enamel defects in Klk4 knockout/LacZ knockin mice

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21 January 2018

How do enamelysin and kallikrein 4 process the 32-kDa enamelin?

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21 January 2018

Kallikrein-related peptidase 12 hydrolyzes matricellular proteins of the CCN family and modifies interactions of CCN1 and CCN5 with growth factors

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21 January 2018

Proteomic profiling of the effect of prostate-specific antigen on prostate cancer cells

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21 January 2018

Proteomic identification of galectin-3 binding ligands and characterization of galectin-3 proteolytic cleavage in human prostasomes

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Growth-inhibitory effect of prostasomes on prostatic cancer cell lines in culture

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21 January 2018

Proteolytic post-translational modification of proteins: proteomic tools and methodology

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Global mapping of the topography and magnitude of proteolytic events in apoptosis

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21 January 2018

Composition of the extracellular matrix of the peritoneum

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Fibroblast and prostate tumor cell cross-talk: Fibroblast differentiation, TGF-β, and extracellular matrix down-regulation

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21 January 2018

Structural characterization and anti-angiogenic properties of prostate-specific antigen isoforms in seminal fluid.

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21 January 2018

Tumor stroma as targets for cancer therapy

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21 January 2018

Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products

1 reference

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21 January 2018

Multiplex N-terminome analysis of MMP-2 and MMP-9 substrate degradomes by iTRAQ-TAILS quantitative proteomics

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21 January 2018

Proteomic analyses reveal an acidic prime side specificity for the astacin metalloprotease family reflected by physiological substrates

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21 January 2018

Tumour microenvironment - opinion: validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy.

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21 January 2018

Substrate specificity of human kallikreins 1 and 6 determined by phage display

1 reference

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21 January 2018

Substrate specificity determination of mouse implantation serine proteinase and human kallikrein-related peptidase 6 by phage display

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21 January 2018

High throughput substrate specificity profiling of serine and cysteine proteases using solution-phase fluorogenic peptide microarrays

1 reference

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21 January 2018

Specificity of human tissue kallikrein towards substrates containing Phe-Phe pair of amino acids

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21 January 2018

Specificity profiling of seven human tissue kallikreins reveals individual subsite preferences

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21 January 2018

Kallikrein-related peptidase-8 (KLK8) is an active serine protease in human epidermis and sweat and is involved in a skin barrier proteolytic cascade

1 reference

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21 January 2018

Enzymatic properties of human kallikrein-related peptidase 12 (KLK12).

1 reference

https://api.crossref.org/works/10.1002%2FPRCA.201300098

21 January 2018

A Multiparametric Panel for Ovarian Cancer Diagnosis, Prognosis, and Response to Chemotherapy

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21 January 2018

Human kallikrein 4: enzymatic activity, inhibition, and degradation of extracellular matrix proteins

1 reference

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21 January 2018

Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1

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21 January 2018

Peptides binding to prostate-specific antigen enhance its antiangiogenic activity

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21 January 2018

Identifiers

10.1002/PRCA.201300098

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

ResearchGate publication ID

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