A self-enforcing CD44s/ZEB1 feedback loop maintains EMT and stemness properties in cancer cells. (Q38863828)

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17 February 2020

title

A self-enforcing CD44s/ZEB1 feedback loop maintains EMT and stemness properties in cancer cells (English)

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17 February 2020

6

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17 February 2020

Ulrich Wellner

7

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17 February 2020

Tilman Brummer

9

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17 February 2020

author name string

Bogdan-Tiberius Preca

1

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17 February 2020

Karolina Bajdak

2

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17 February 2020

Kerstin Mock

3

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17 February 2020

Vignesh Sundararajan

4

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17 February 2020

Jessica Pfannstiel

5

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17 February 2020

Ulrich T Hopt

8

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17 February 2020

Simone Brabletz

10

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17 February 2020

Thomas Brabletz

11

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17 February 2020

Marc P Stemmler

12

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17 February 2020

language of work or name

English

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publication date

30 June 2015

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International Journal of Cancer

17 February 2020

published in

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volume

137

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17 February 2020

issue

11

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17 February 2020

page(s)

2566-2577

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Complex networks orchestrate epithelial-mesenchymal transitions

17 February 2020

cites work

1 reference

Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis

21 January 2018

1 reference

Regulatory networks defining EMT during cancer initiation and progression

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1 reference

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The epithelial-mesenchymal transition generates cells with properties of stem cells

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Generation of breast cancer stem cells through epithelial-mesenchymal transition

21 January 2018

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The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

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Cancer stem cells: mirage or reality?

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Unravelling cancer stem cell potential.

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Dormancy and breast cancer

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Prospective identification of tumorigenic breast cancer cells

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Prospective identification of tumorigenic prostate cancer stem cells

21 January 2018

1 reference

Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells

21 January 2018

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Identification of pancreatic cancer stem cells

21 January 2018

1 reference

Phenotypic characterization of human colorectal cancer stem cells

21 January 2018

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CD44 is required for two consecutive steps in HGF/c-Met signaling.

21 January 2018

1 reference

CD44: can a cancer-initiating cell profit from an abundantly expressed molecule?

21 January 2018

1 reference

CD44 integrates signaling in normal stem cell, cancer stem cell and (pre)metastatic niches

21 January 2018

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CD44: from adhesion molecules to signalling regulators

21 January 2018

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ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing

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A novel MCF-10A line allowing conditional oncogene expression in 3D culture

21 January 2018

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A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer

21 January 2018

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Zeb1 regulates E-cadherin and Epcam (epithelial cell adhesion molecule) expression to control cell behavior in early zebrafish development

21 January 2018

1 reference

Down-regulation of the homeodomain factor Cdx2 in colorectal cancer by collagen type I: an active role for the tumor environment in malignant tumor progression

21 January 2018

1 reference

A strategy for predicting the chemosensitivity of human cancers and its application to drug discovery

21 January 2018

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The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

21 January 2018

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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

21 January 2018

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Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations

21 January 2018

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Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis

21 January 2018

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Integration of metabolomics and transcriptomics revealed a fatty acid network exerting growth inhibitory effects in human pancreatic cancer

21 January 2018

1 reference

DPEP1 inhibits tumor cell invasiveness, enhances chemosensitivity and predicts clinical outcome in pancreatic ductal adenocarcinoma

21 January 2018

1 reference

CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression

21 January 2018

1 reference

TGF-β drives epithelial-mesenchymal transition through δEF1-mediated downregulation of ESRP.

21 January 2018

1 reference

Snail represses the splicing regulator epithelial splicing regulatory protein 1 to promote epithelial-mesenchymal transition

21 January 2018

1 reference

Development and characterization of gemcitabine-resistant pancreatic tumor cells.

21 January 2018

1 reference

miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions

21 January 2018

1 reference

Correlation of CD44v6 expression with ovarian cancer progression and recurrence

21 January 2018

1 reference

CD44 expression is associated with increased survival in node-negative invasive breast carcinoma

21 January 2018

1 reference

Upregulated CD44v9 expression inhibits the invasion of oral squamous cell carcinoma cells

21 January 2018

1 reference

CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving colon cancer metastasis.

21 January 2018

1 reference

Stem cell CD44v isoforms promote intestinal cancer formation in Apc(min) mice downstream of Wnt signaling

21 January 2018

1 reference

Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing

21 January 2018

1 reference

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

21 January 2018

1 reference

Regulation of microRNA expression by hepatocyte growth factor in human head and neck squamous cell carcinoma

21 January 2018

1 reference

CD44v3 levels in primary cutaneous melanoma are predictive of prognosis: Assessment by the use of tissue microarray

21 January 2018

1 reference

Stem Cells and Cancer: Two Faces of Eve

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IJC.29642

1 reference

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17 February 2020

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