An auto-regulatory loop between stress sensors INrf2 and Nrf2 controls their cellular abundance. (Q40070103)

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8 January 2020

title

An auto-regulatory loop between stress sensors INrf2 and Nrf2 controls their cellular abundance (English)

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8 January 2020

2

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8 January 2020

author name string

Ok-Hee Lee

series ordinal

1

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8 January 2020

Victor Papusha

series ordinal

3

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8 January 2020

Anil K Jaiswal

series ordinal

4

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8 January 2020

language of work or name

English

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publication date

9 October 2007

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Journal of Biological Chemistry

8 January 2020

published in

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8 January 2020

volume

282

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8 January 2020

issue

50

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8 January 2020

page(s)

36412-36420

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Reactions of oxyl radicals with DNA.

8 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Molecular basis for the contribution of the antioxidant responsive element to cancer chemoprevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Transcription factor Nrf2/MafK regulates rat placental glutathione S-transferase gene during hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Nuclear factor Nrf2 and antioxidant response element regulate NRH:quinone oxidoreductase 2 (NQO2) gene expression and antioxidant induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

The GI-GPx gene is a target for Nrf2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Human prx1 gene is a target of Nrf2 and is up-regulated by hypoxia/reoxygenation: implication to tumor biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Nrf2 signaling in coordinated activation of antioxidant gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

GSK-3beta acts upstream of Fyn kinase in regulation of nuclear export and degradation of NF-E2 related factor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Phosphorylation of tyrosine 568 controls nuclear export of Nrf2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Nuclear import and export signals in control of Nrf2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200

Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M706517200