dronedarone (Q408637)

Dronedarone (English)

3 October 2016

chemical formula

C₃₁H₄₄N₂O₅S

1 reference

Dronedarone (English)

19 November 2016

canonical SMILES

CCCCC1=C(C2=C(O1)C=CC(=C2)NS(=O)(=O)C)C(=O)C3=CC=C(C=C3)OCCCN(CCCC)CCCC

1 reference

Dronedarone (English)

https://www.whocc.no/atc_ddd_index/?code=C01BD07

19 November 2016

defined daily dose

0.8 gram

route of administration

oral administration

1 reference

reference URL

1 reference

14 February 2018

World Health Organisation international non-proprietary name

dronedarone (English)

1 reference

dronedarone (English)

medical condition treated

3 October 2016

heart arrhythmia

1 reference

Drug Indications Extracted from FAERS

2 October 2018

atrial fibrillation

1 reference

Drug Indications Extracted from FAERS

significant drug interaction

2 October 2018

amiodarone

1 reference

High-priority drug–drug interactions for use in electronic health records

anagrelide

1 reference

High-priority drug–drug interactions for use in electronic health records

arsenic trioxide

1 reference

High-priority drug–drug interactions for use in electronic health records

astemizole

1 reference

High-priority drug–drug interactions for use in electronic health records

azithromycin

1 reference

High-priority drug–drug interactions for use in electronic health records

bepridil

1 reference

High-priority drug–drug interactions for use in electronic health records

chloroquine

1 reference

High-priority drug–drug interactions for use in electronic health records

chlorpromazine

1 reference

High-priority drug–drug interactions for use in electronic health records

cisapride

1 reference

High-priority drug–drug interactions for use in electronic health records

(RS)-citalopram

1 reference

High-priority drug–drug interactions for use in electronic health records

clarithromycin

1 reference

High-priority drug–drug interactions for use in electronic health records

cocaine

1 reference

High-priority drug–drug interactions for use in electronic health records

disopyramide

1 reference

High-priority drug–drug interactions for use in electronic health records

dofetilide

1 reference

High-priority drug–drug interactions for use in electronic health records

domperidone

1 reference

High-priority drug–drug interactions for use in electronic health records

droperidol

1 reference

High-priority drug–drug interactions for use in electronic health records

erythromycin

1 reference

High-priority drug–drug interactions for use in electronic health records

escitalopram

1 reference

High-priority drug–drug interactions for use in electronic health records

flecainide

1 reference

High-priority drug–drug interactions for use in electronic health records

halofantrine

1 reference

High-priority drug–drug interactions for use in electronic health records

haloperidol

1 reference

High-priority drug–drug interactions for use in electronic health records

ibutilide

1 reference

High-priority drug–drug interactions for use in electronic health records

mesoridazine

1 reference

High-priority drug–drug interactions for use in electronic health records

(RS)-methadone

1 reference

High-priority drug–drug interactions for use in electronic health records

moxifloxacin

1 reference

High-priority drug–drug interactions for use in electronic health records

ondansetron

1 reference

High-priority drug–drug interactions for use in electronic health records

pentamidine

1 reference

High-priority drug–drug interactions for use in electronic health records

pimozide

1 reference

High-priority drug–drug interactions for use in electronic health records

probucol

1 reference

High-priority drug–drug interactions for use in electronic health records

procainamide

1 reference

High-priority drug–drug interactions for use in electronic health records

quinidine

1 reference

High-priority drug–drug interactions for use in electronic health records

sevoflurane

1 reference

High-priority drug–drug interactions for use in electronic health records

sotalol

1 reference

High-priority drug–drug interactions for use in electronic health records

sparfloxacin

1 reference

High-priority drug–drug interactions for use in electronic health records

(RS)-sulpiride

1 reference

High-priority drug–drug interactions for use in electronic health records

terfenadine

1 reference

High-priority drug–drug interactions for use in electronic health records

thioridazine

1 reference

High-priority drug–drug interactions for use in electronic health records

ondansetron

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-methadone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

amiodarone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

arsenic trioxide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

disopyramide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

toremifene

1 reference

A reference set of clinically relevant adverse drug-drug interactions

flecainide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

sotalol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

anagrelide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

moxifloxacin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

erythromycin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

levomepromazine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-sulpiride

1 reference

A reference set of clinically relevant adverse drug-drug interactions

vandetanib

1 reference

A reference set of clinically relevant adverse drug-drug interactions

crizotinib

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pasireotide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

droperidol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

haloperidol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-hydroxyzine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

chlorpromazine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-citalopram

1 reference

A reference set of clinically relevant adverse drug-drug interactions

zuclopenthixol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pentamidine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

mefloquine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bendroflumethiazide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

chlorthalidone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(2RS,6RS)-clopamide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bumetanide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

furosemide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

hydrochlorothiazide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

indapamide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

fingolimod

1 reference

A reference set of clinically relevant adverse drug-drug interactions

domperidone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

voriconazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

clarithromycin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pimozide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

fluphenazine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ivabradine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

fluphenazine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-propafenone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ivabradine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

fosphenytoin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

tacrolimus

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-metoprolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

nadolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

atenolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

nebivolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

acebutolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

betaxolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bisoprolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pindolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

carvedilol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

propranolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

labetalol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

celiprolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

esmolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

levobunolol

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bendroflumethiazide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

chlorthalidone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(2RS,6RS)-clopamide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bumetanide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

furosemide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

hydrochlorothiazide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

indapamide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

posaconazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

itraconazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

voriconazole

1 reference

A reference set of clinically relevant adverse drug-drug interactions

clarithromycin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pimozide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

Ketoconazole

1 reference

established

A reference set of clinically relevant adverse drug-drug interactions

legal status (medicine)

boxed warning

1 reference

reference URL

https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802

imported from Wikimedia project

FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (English)

pregnancy category

US pregnancy category X

1 reference

English Wikipedia

LiverTox likelihood score

LiverTox toxicity likelihood category C

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Dronedarone

last update

5 January 2018

schematic

Dronedarone synth.png
3,696 × 2,392; 313 KB

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Commons category

Dronedarone

0 references

Identifiers

InChI

InChI=1S/C31H44N2O5S/c1-5-8-12-29-30(27-23-25(32-39(4,35)36)15-18-28(27)38-29)31(34)24-13-16-26(17-14-24)37-22-11-21-33(19-9-6-2)20-10-7-3/h13-18,23,32H,5-12,19-22H2,1-4H3

1 reference

Dronedarone (English)

19 November 2016

2 references

Dronedarone (English)

19 November 2016

ChEBI release 2020-09-01

CAS Registry Number

141626-36-0

2 references

dronedarone (English)

19 November 2016

https://commonchemistry.cas.org/detail?cas_rn=141626-36-0

10 April 2021

1 reference

Dronedarone (English)

19 November 2016

2 references

Dronedarone (English)

19 November 2016

Reaxys registry number

8176529

1 reference

dronedarone (English)

3 October 2016

ChEBI ID

50659

mapping relation type

2 references

DRONEDARONE (English)

19 November 2016

International Chemical Identifier

InChI

InChI=1S/C31H44N2O5S/c1-5-8-12-29-30(27-23-25(32-39(4,35)36)15-18-28(27)38-29)31(34)24-13-16-26(17-14-24)37-22-11-21-33(19-9-6-2)20-10-7-3/h13-18,23,32H,5-12,19-22H2,1-4H3

1 reference

DRONEDARONE (English)

19 November 2016

2 references

inferred from InChIKey

MSBNK-Athens_Univ-AU218101

1 reference

MassBank accession ID

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MSBNK-Athens_Univ-AU218102

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MSBNK-Athens_Univ-AU218103

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MSBNK-Athens_Univ-AU218104

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MSBNK-Athens_Univ-AU218105

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MSBNK-Athens_Univ-AU218107

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MSBNK-Athens_Univ-AU218108

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MSBNK-Athens_Univ-AU218109

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MSBNK-Athens_Univ-AU218110

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MSBNK-Athens_Univ-AU218111

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MSBNK-Athens_Univ-AU218130

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MSBNK-Athens_Univ-AU218131

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MSBNK-Athens_Univ-AU218132

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MSBNK-Athens_Univ-AU218133

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MSBNK-Athens_Univ-AU218151

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MSBNK-Athens_Univ-AU218152

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MSBNK-Athens_Univ-AU218153

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MSBNK-Athens_Univ-AU218154

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MSBNK-Athens_Univ-AU218155

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splash10-0a4i-0000090000-a4ea4fac6f54cdcb7cbc

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splash10-0a4i-0000090000-c3aef714c9268fa971ca

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splash10-0a4i-0100290000-55925fc920832a562317

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splash10-052o-0922440000-21a75dc14e4f6eec2a80

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splash10-0a4i-0000090000-8897a71d0d4436083f2f

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splash10-0a4i-0000090000-0412b5e5e921a14ade8e

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splash10-0a4i-0000090000-77777b7e67d24302cc61

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splash10-0a4i-0000090000-98e3b8bdab6f810350d0

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splash10-0a4i-0009020000-46fc09138b4d4c98f7db

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splash10-000i-0011920000-b36c2c2ac812fdf862c0

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splash10-0a4i-0000090000-6af26e1e5383a4521666

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splash10-0a4i-0000090000-8a1e04d2d220b7c178b7

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splash10-0udl-1900000000-1526ae7b1c72d66d17f7

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splash10-0zfr-3900000000-5720b31639362bc77d45

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splash10-0pb9-6900000000-5862d8b2fbe4b55544fd

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splash10-0a4i-9800000000-52425d2c67f0ee9e6833

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splash10-0a4i-0000090000-91af4261328f04d47762

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splash10-0a4i-0000090000-e6261075748cb68a6673

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splash10-0udl-1900000000-b6ee80d1389866275d10

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splash10-0zfr-3900000000-79bd8a4d5fb81c2d7697

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splash10-0zfr-6900000000-45b09ec3acdb68cc2d94

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splash10-0a4i-9810000000-e53f3747472fb6644b74

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splash10-000i-0011920000-32cc8203ba76ec3246f7

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HSDB ID

7928

1 reference

Hazardous Substances Data Bank

28 October 2019

Dronedarone (English)

10 May 2021

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.109.411

27 December 2018

ECHA Substance Infocard ID

N-(2-butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl)methanesulfonamide (English)

quotation

CAS no.: 141626-36-0 (English)

100.109.411

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.109.411

27 December 2018

N-(2-butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl)methanesulfonamide (English)

quotation

CAS no.: 141626-36-0 (English)

1 reference

Guide to Pharmacology Ligand ID

Dronedarone (English)

publication date

17 November 2015

7465

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

7465

dronedarone (English)

19 November 2016

Dronedarone

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MeSH concept ID

M0304036

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MeSH tree code

D03.633.100.127.075.500

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RxNorm ID

233698

1 reference

dronedarone (English)

19 November 2016

DrugBank ID

DB04855

1 reference

Human Metabolome Database ID

HMDB0251621

2 references

based on heuristic

inferred from InChIKey

2 references

dronedarone (English)

19 November 2016

MedlinePlus drug identifier

a609034

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PatientsLikeMe treatment ID

0 references

1 reference

dronedarone (English)

19 November 2016

0 references

1 reference

1 reference

https://docs.openalex.org/download-snapshot/snapshot-data-format

dronedarone (English)

3 October 2016

0 references

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

UMLS CUI

C0766326

1 reference

dronedarone (English)