Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53-dependent cellular senescence (Q42053248)

15 October 2017

Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53-dependent cellular senescence (English)

1 reference

15 October 2017

3

1 reference

15 October 2017

Wilfredo Cosme-Blanco

1

1 reference

15 October 2017

Mei-Feng Shen

2

1 reference

15 October 2017

Sen Pathak

4

1 reference

15 October 2017

Guillermina Lozano

5

1 reference

15 October 2017

Asha S Multani

6

1 reference

15 October 2017

Sandy Chang

7

1 reference

15 October 2017

30 March 2007

1 reference

15 October 2017

1 reference

15 October 2017

8

1 reference

15 October 2017

5

1 reference

15 October 2017

497-503

1 reference

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

15 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

Ras mutation promotes p53 activation and apoptosis of skin keratinocytes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

Shelterin: the protein complex that shapes and safeguards human telomeres

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

BRAFE600-associated senescence-like cell cycle arrest of human naevi

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

Tumour biology: senescence in premalignant tumours

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

Intrinsic tumour suppression

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

A DNA damage checkpoint response in telomere-initiated senescence

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

DNA damage foci at dysfunctional telomeres

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

Connecting chromosomes, crisis, and cancer

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

Proliferation, cell cycle and apoptosis in cancer

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

Oncogene-induced senescence as an initial barrier in lymphoma development

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

In situ analyses of genome instability in breast cancer

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

Telomere dysfunction provokes regional amplification and deletion in cancer genomes.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866197

The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability

17 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.EMBOR.7400937

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.EMBOR.7400937

Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17396137

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17396137

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Telomere length abnormalities occur early in the initiation of epithelial carcinogenesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17396137

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.EMBOR.7400937

1 reference

15 October 2017

1 reference

15 October 2017

PubMed publication ID

17396137

1 reference