Brain Regions Showing White Matter Loss in Huntington's Disease Are Enriched for Synaptic and Metabolic Genes (Q45305662)

7 July 2018

title

Brain Regions Showing White Matter Loss in Huntington's Disease Are Enriched for Synaptic and Metabolic Genes (English)

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7 July 2018

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10

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Eileanoir B. Johnson

Eileanoir Johnson

6

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Marina Papoutsi

Marina Papoutsi

5

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Alexandra Durr

7

Alexandra Durr

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9

Blair R Leavitt

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Raymund A. C. Roos

8

Raymund A C Roos

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Sarah J. Tabrizi

14

Sarah J Tabrizi

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Rachael I. Scahill

11

Rachael I Scahill

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7 July 2018

Geraint Rees

13

Geraint Rees

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7 July 2018

Kiran K Seunarine

3

Kiran K Seunarine

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4

Adeel Razi

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7 July 2018

Peter McColgan

1

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Sarah Gregory

2

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Chris A Clark

12

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Track-On HD Investigators

15

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7 July 2018

language of work or name

English

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publication date

26 October 2017

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7 July 2018

published in

Biological Psychiatry

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7 July 2018

volume

83

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7 July 2018

issue

5

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7 July 2018

page(s)

456-465

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7 July 2018

Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study

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RNA-Seq of Huntington's disease patient myeloid cells reveals innate transcriptional dysregulation associated with proinflammatory pathway activation.

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Structural and molecular myelination deficits occur prior to neuronal loss in the YAC128 and BACHD models of Huntington disease

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Linking white matter and deep gray matter alterations in premanifest Huntington disease

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Compensation in Preclinical Huntington's Disease: Evidence From the Track-On HD Study

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Disruption of immune cell function by mutant huntingtin in Huntington's disease pathogenesis

10 July 2018

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Network structure of brain atrophy in de novo Parkinson's disease

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Identification of Genetic Factors that Modify Clinical Onset of Huntington's Disease

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Corticostriatal synaptic adaptations in Huntington's disease

10 July 2018

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Fiber estimation and tractography in diffusion MRI: development of simulated brain images and comparison of multi-fiber analysis methods at clinical b-values

10 July 2018

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Genetic variability in the regulation of gene expression in ten regions of the human brain

10 July 2018

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Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease

10 July 2018

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10 July 2018

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3-Nitropropionic acid modifies neurotrophin mRNA expression in the mouse striatum: 18S-rRNA is a reliable control gene for studies of the striatum

10 July 2018

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Predicting regional neurodegeneration from the healthy brain functional connectome

10 July 2018

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Multimodal MRI analysis of the corpus callosum reveals white matter differences in presymptomatic and early Huntington's disease.

10 July 2018

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10 July 2018

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What have we learned from gene expression profiles in Huntington's disease?

10 July 2018

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Peroxisome-proliferator-activated receptor gamma coactivator 1 α contributes to dysmyelination in experimental models of Huntington's disease

10 July 2018

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10 July 2018

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10 July 2018

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Decreased Lin7b expression in layer 5 pyramidal neurons may contribute to impaired corticostriatal connectivity in huntington disease

10 July 2018

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Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data

10 July 2018

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10 July 2018

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10 July 2018

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10 July 2018

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10 July 2018

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Regional and cellular gene expression changes in human Huntington's disease brain

10 July 2018

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Co-localization of brain-derived neurotrophic factor (BDNF) and wild-type huntingtin in normal and quinolinic acid-lesioned rat brain

10 July 2018

1 reference

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Mitochondrial dysfunction and free radical damage in the Huntington R6/2 transgenic mouse.

10 July 2018

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Healthy brain connectivity predicts atrophy progression in non-fluent variant of primary progressive aphasia

10 July 2018

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Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice.

15 August 2018

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SIFT2: Enabling dense quantitative assessment of brain white matter connectivity using streamlines tractography

15 August 2018

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The effects of SIFT on the reproducibility and biological accuracy of the structural connectome

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5803509

Determination of the appropriate b value and number of gradient directions for high-angular-resolution diffusion-weighted imaging.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5803509

Investigating the prevalence of complex fiber configurations in white matter tissue with diffusion magnetic resonance imaging

15 August 2018

1 reference

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15 August 2018

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Early changes in white matter pathways of the sensorimotor cortex in premanifest Huntington's disease

15 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5803509

Diminished activity-dependent brain-derived neurotrophic factor expression underlies cortical neuron microcircuit hypoconnectivity resulting from exposure to mutant huntingtin fragments

15 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5803509

15 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5803509

10.1016/J.BIOPSYCH.2017.10.019

15 August 2018

Identifiers

DOI

1 reference

7 July 2018

release_5dvl436wyrf3bf7fr2x7sm6axe

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/5dvl436wyrf3bf7fr2x7sm6axe

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

5803509

1 reference

7 July 2018

PubMed publication ID

29174593

1 reference

7 July 2018