GPI 트랜스아미다아제 성분 PIG-S는 PIGS [5] 유전자 에 의해 인체에서 코드되는 효소 이다.이 유전자는 GPI 앵커 생합성 에 관여하는 단백질을 암호화한다.
글리코실포스파티딜이노시톨 (GPI) 앵커는 많은 혈액 세포에서 발견되는 당지질 이며 단백질을 세포 표면에 고정시키는 역할을 한다.이 유전자는 다중 서브유닛 효소의 필수 성분인 GPI 트랜스아미다아제 를 암호화합니다. GPI 트랜스아미다아제는 완전히 조립된 GPI 단위의 단백질 [5] 전달을 촉매함으로써 GPI를 내소체망 내 에 고정시킨다.
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