GIL sistem antigena
Antigeni GIL sistema je nekadašnji naziv za Aquaporin 3 (AQP3), koji je otkriven u bazolateralnim ćelijskim membranama glavnog sabirnog kanala, a omogućava put izlaska vode iz ćelije.[5] U bubregu se ispoljavanje AQP3 gena regulira vazopresinom (ADH). Ovaj protein je isključiva determinanta GIL sistema krvnih grupa.[6]
Reference
[uredi | uredi izvor]- ^ a b c GRCh38: Ensembl release 89: ENSG00000165272 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028435 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Sasaki S., Ishibashi K., Marumo F. (1998): Aquaporin-2 and -3: representatives of two subgroups of the aquaporin family colocalized in the kidney collecting duct. Annu. Rev. Physiol., 60: 199–220.
- ^ Roudier N., Ripoche P., Gane P., Le Pennec P. Y., Daniels G., Cartron J. P., Bailly P. (2002): AQP3 deficiency in humans and the molecular basis of a novel blood group system, GIL. J. Biol. Chem., 277 (48): 45854–45859.