TARS

TARS1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1WWT, 4HWT, 4P3N, 4TTV
Dynodwyr
Cyfenwau	TARS1, ThrRS, threonyl-tRNA synthetase, TARS, threonyl-tRNA synthetase 1, TTD7
Dynodwyr allanol	OMIM: 187790 HomoloGene: 11852 GeneCards: TARS1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • aminoacyl-tRNA ligase activity • nucleotide binding • ligase activity • GO:0001948, GO:0016582 protein binding • ATP binding • protein homodimerization activity • threonine-tRNA ligase activity • tRNA binding • RNA binding Cydrannau o'r gell • extracellular exosome • actin cytoskeleton • cytoplasm • cytosol Prosesau biolegol • tRNA aminoacylation • tRNA aminoacylation for protein translation • protein biosynthesis • threonyl-tRNA aminoacylation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6897	n/a
Ensembl	ENSG00000113407	n/a
UniProt	P26639	n/a
RefSeq (mRNA)	NM_001258437 NM_001258438 NM_152295	n/a
RefSeq (protein)	NP_001245366 NP_001245367 NP_689508	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TARS yw TARS a elwir hefyd yn Threonine--tRNA ligase, cytoplasmic a Threonyl-tRNA synthetase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 5, band 5p13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TARS.

• ThrRS

Llyfryddiaeth

• "Kinetic mechanism of threonyl-tRNA synthetase from human placenta. ". Int J Pept Protein Res. 1982. PMID 7118437.
• "Purification and subunit structure studies of human placental threonyl-tRNA synthetase. ". Int J Pept Protein Res. 1982. PMID 7118399.
• "Threonyl-tRNA synthetase overexpression correlates with angiogenic markers and progression of human ovarian cancer. ". BMC Cancer. 2014. PMID 25163878.
• "Secreted Threonyl-tRNA synthetase stimulates endothelial cell migration and angiogenesis. ". Sci Rep. 2013. PMID 23425968.
• "Clinical manifestations and outcome of anti-PL7 positive patients with antisynthetase syndrome.". Eur J Intern Med. 2013. PMID 23375620.