Mismatch Quotes

Quotes tagged as "mismatch" Showing 1-19 of 19
Tara Westover
“The conversation was slow, halting. Audrey asked me no questions about England or Cambridge. She had no frame of reference for my life, so we talked about hers”
Tara Westover, Educated

Tara Westover
“I tried to imagine what it would have been like to study at such a place, to walk across marble floors each morning and, day after day, come to associate learning with beauty. But my imagination failed me. I could only imagine the school as I was experiencing it now, as a kind of museum, a relic from someone else’s life”
Tara Westover, Educated

“The arbiter of a demanding wargame rendered the word "mismatch" as "challenge" in his language.”
Star Trek The Next Generation

“While natural selection is expected -all else being equal- to weed out traits that have become detrimental to fitness, the process may often take a long time. This generates the potential for mismatch between and organism's adaptations and its present environment.”
Marco del Giudice, Evolutionary Psychopathology: A Unified Approach

Randolph M. Nesse
“Criminalization and interdiction have filled prisons and corrupted governments in country after country. However, increasingly potent drugs that can be synthetized in any basement make controlling access increasingly impossible. Legalization seems like a good idea but causes more addiction. Our strongest defense is likely to be education, but scare stories make kids want to try drugs. Every child should learn that drugs take over the brain and turn some people into miserable zombies and that we have no way to tell who will get addicted the fastest. They should also learn that the high fades as addiction takes over.”
Randolph M. Nesse, Good Reasons for Bad Feelings: Insights from the Frontier of Evolutionary Psychiatry

Randolph M. Nesse
“Most chemicals that give humans a buzz evolved to disrupt insect nervous systems. If our brains used different chemicals, we would not be so vulnerable. However, we have common ancestors with insects. It was long ago, about 500 million years ago, when our ancestors split off from the arthropod lines that became modern insects. However, our neurochemicals remain about the same as theirs. Fortunately, most plant neurotoxins don’t kill us. We have evolved to eat plants, and we are much larger than insects, so low doses are not fatal. But drugs can hijack our motivation mechanisms and take control of our lives.”
Randolph M. Nesse, Good Reasons for Bad Feelings: Insights from the Frontier of Evolutionary Psychiatry

R.H. Sin
“she accepted a love
that never matched
her own”
R.H. Sin, Algedonic

Daniel E. Lieberman
“Most of the mismatch diseases from which we currently suffer stem from the transition from hunting and gathering to farming.”
Daniel E. Lieberman, The Story of the Human Body: Evolution, Health, and Disease

“If, though, the phenotype then encountered an environment richer than expected, the thrifty phenotype might be -mismatched- to the greater abundance. It is this mismatch, it is argued, that has led to the prosperity for adults to develop obesity and other metabolic disorders during adulthood in our contemporary, industrialised environments.”
Kimberly A. Plomp, Palaeopathology and Evolutionary Medicine: An Integrated Approach

“Once industrialisation ocurred, non-communicable (chronic) diseases (NCDs; e.g., cancers, cardiovascular disease, diabetes, cardio-vascular, and non-infectious respiratory diseases) started to rise and replace infections. Tobacco use, physical inactivity, unhealthy diets and the harmful use of alcohol are key risk factors for NCDs.”
Kimberly A. Plomp, Palaeopathology and Evolutionary Medicine: An Integrated Approach

“The idea of mismatch is based on the fact that adaptations are shaped by selection within a given environment. If the environment changes rapidly and radically, some biological systems run the risk of becoming mismatched to the new environment. This is also referred to as -genome lag-.”
Riadh Abed, Evolutionary Psychiatry: Current Perspectives on Evolution and Mental Health

Randolph M. Nesse
“Many of our current health problems result, nonetheless, from the environments we have created to satisfy our desires. Most people in developed societies live better now physically than the kings and queens of just a century ago. We have a surfeit of delicious food, protection from the elements, time for leisure, and relief from pain. The accomplishments are spectacular, but they also cause most chronic disease.”
Randolph M. Nesse, Good Reasons for Bad Feelings: Insights from the Frontier of Evolutionary Psychiatry

Randolph M. Nesse
“Treatment of eating disorders is improved by the recognition that strenuous dieting arouses famine protection mechanisms that are prone to initiate a positive feedback spiral.”
Randolph M. Nesse, Good Reasons for Bad Feelings: Insights from the Frontier of Evolutionary Psychiatry

Randolph M. Nesse
“Eating disorders were not shaped by selection, but mechanisms that regulate eating during famines were. ADHD was not shaped by selection, but mechanisms that regulate attention were. Serious depression was not shaped by natural selection, but capacities for normal low and high mood were.”
Randolph M. Nesse, Good Reasons for Bad Feelings: Insights from the Frontier of Evolutionary Psychiatry

Randolph M. Nesse
“Eating disorders are not caused by abnormal genes; they are caused by normal genes interacting with abnormal environments.”
Randolph M. Nesse, Good Reasons for Bad Feelings: Insights from the Frontier of Evolutionary Psychiatry

Randolph M. Nesse
“Patients with anorexia nervosa and bulimia nervosa are surrounded by excess food, but their bodies are aware only of starvation. Their behavior is appropriate for a situation in which getting just a few extra calories might make the difference between life and death.”
Randolph M. Nesse, Good Reasons for Bad Feelings: Insights from the Frontier of Evolutionary Psychiatry

Randolph M. Nesse
“The starting point is recognizing that selection has shaped powerful mechanisms to protect against starvation. During a famine, those mechanisms motivate animals to get food -any food- eat it quickly, and eat more than usual, because food supplies are obviously erratic. The system also adjusts the body weight set point upward because extra fat stores are valuable when food sources are unreliable. And, as noted already, weight loss slows down metabolism, which is appropriate when a person is starving but the opposite of what is needed when trying to lose weight. Also, intermittent access to food signals unreliable access to food supplies, so it increases food intake and bingeing, even in rats.”
Randolph M. Nesse, Good Reasons for Bad Feelings: Insights from the Frontier of Evolutionary Psychiatry

Randolph M. Nesse
“The trajectory is clear: our minds have always been vulnerable to capture by alcohol, marijuana, tobacco, coca, and opium, but problems with them have escalated as advances in chemistry, transportation, and technology have increased the diversity, purity, and availability of drugs. The mismatch was bad before; now it’s getting much worse.”
Randolph M. Nesse, Good Reasons for Bad Feelings: Insights from the Frontier of Evolutionary Psychiatry