The document outlines the pathophysiology of acute renal failure, including predisposing factors like age, sex, and race. It then describes the process by which decreased renal blood flow leads to activation of the renin-angiotensin-aldosterone system and vasoconstriction, increasing blood pressure and decreasing tissue perfusion. If not treated, this can progress to renal impairment, insufficiency, failure and eventually end-stage renal disease and death. Treatment includes dialysis, medications to control blood pressure and fluid levels.
The document outlines the pathophysiology of acute renal failure, including predisposing factors like age, sex, and race. It then describes the process by which decreased renal blood flow leads to activation of the renin-angiotensin-aldosterone system and vasoconstriction, increasing blood pressure and decreasing tissue perfusion. If not treated, this can progress to renal impairment, insufficiency, failure and eventually end-stage renal disease and death. Treatment includes dialysis, medications to control blood pressure and fluid levels.
- Dialysis - Antihypertensive Meds - Diuretics - etc. Good Prognosis/ Poor Prognosis Recurrent ARF (It depends on the patient’s Coping abilities) Further damage to the glomeruli
Hypertrophy of the remaining
healthy glomeruli
A number of the hyperthrophied
glomeruli dies Signs and Symptoms: - Nocturia - fatigue Renal Impairment (40-50% - lassitude remaining GFR) - anorexia - uremia
