RCT Appraisal Sheets 2005 English-2
RCT Appraisal Sheets 2005 English-2
RCT Appraisal Sheets 2005 English-2
THERAPY STUDY:Are
2a. A Aside from the allocated treatment, were groups treated equally?
What is best?
Apart from the intervention the patients in the
different groups should be treated the same,
eg., additional treatments or tests.
This paper: Yes No Unclear
Comment:
2b. A Were all patients who entered the trial accounted for? and were they
analysed in the groups to which they were randomised?
What is best?
Losses to follow-up should be minimal
preferably less than 20%. However, if few
patients have the outcome of interest, then
even small losses to follow-up can bias the
results. Patients should also be analysed in the
groups to which they were randomised
intention-to-treat analysis.
This paper: Yes No Unclear
Comment:
3. M - Were measures objective or were the patients and clinicians kept blind
to which treatment was being received?
What is best?
It is ideal if the study is double-blinded that
is, both patients and investigators are unaware
of treatment allocation. If the outcome is
objective (eg., death) then blinding is less
critical. If the outcome is subjective (eg.,
symptoms or function) then blinding of the
patients' treatment.
Unclear