Drug Study

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DOSAGE,

NAME OF MECHANISM OF INDICATION AND NURSING


FREQ., SIDE EFFECTS
DRUG ACTION CONTRAINDICATION RESPONSIBILITIES
ROUTE

Generic Name: July 10 Salbutamol Indication CNS: nervousness, - Assess lung sounds,
Salbutamol + - Q4 (4 - Binds to beta2- - Used as a quick- restlessness, pulse, and blood
Ipratropium doses) adrenergic relief agent for acute tremor, headache, pressure before
- Inhalation receptors in airway bronchospasm and insomnia, dizziness administration and
Brand Name: smooth muscle, for prevention of during peak of
Multivent Shifted to leading to exercise-induced Resp: medication.
- Q6 activation of bronchospasm. bronchospasm, - Assess respiratory
Classification: - Inhalation adenyl cyclase - Maintenance therapy cough status (rate, breath
bronchodilator and increased of reversible airway sounds, degree of
levels of cyclic-3, obstruction due to CV: chest pain, dyspnea, pulse) before
5-adenosine COPD, including palpitations, angina, administration and
monophosphate chronic bronchitis arrhythmias, peak of medication.
(cAMP). and emphysema. hypertension - Observe paradoxical
bronchospasm
Ipratropium Contraindication GI: nausea, (wheezing). If condition
- Inhibits cholinergic - Hypersensitivity to vomiting occurs, withhold
receptors in adrenergic amines. medication and notify
bronchial smooth - Hypersensitivity to Endo: the doctor.
muscle, resulting ipratropium, hyperglycemia
in decreased atropine, bromide; Lab Test Consideration
concentrations of avoid using during F and E: - May cause transient
cyclic guanosine acute hypokalemia increase in serum
monophosphate bronchospasm. potassium
(cGMP). Neuro: tremor concentrations with
nebulization or higher-
than-recommended
doses.
DOSAGE,
NAME OF MECHANISM OF INDICATION AND NURSING
FREQ., SIDE EFFECTS
DRUG ACTION CONTRAINDICATION RESPONSIBILITIES
ROUTE

Generic Name: July 10 - Suppress Indication CNS: depression, - Monitor intake and
Hydrocortisone - 10mg inflammation and - Used systemically euphoria, headache, output ratios and daily
- Q8 the normal and locally in a wide restlessness. weights. Observe
Brand Name: - IV immune response. variety of chronic patient for peripheral
Cortenema diseases including: CV: hypertension edema, steady weight
July 17 Therapeutic Effect: Inflammatory. gain, rale/crackles, or
Classification: - D/C 8pm - Suppression of GI: peptic dyspnea.
Corticosteroid inflammation and Contraindication ulceration, anorexia,
(short-acting) modification of the - Active untreated nausea, vomiting. Lab Test Consideration:
normal immune infections. - Monitor serum
response. Derm: decrease electrolytes and
wound healing glucose. May cause
hypokalemia.
Endo: - Patient on prolonged
hyperglycemia therapy should
routinely have CBC,
F and E: fluid serum electrolytes, and
retention (long-term serum and urine
high doses), glucose evaluated.
hypokalemia,
hypokalemic
alkalosis.

Metab: weight gain

Misc: cushingoid
appearance (moon
face, buffalo hump)
DOSAGE,
NAME OF MECHANISM OF INDICATION AND NURSING
FREQ., SIDE EFFECTS
DRUG ACTION CONTRAINDICATION RESPONSIBILITIES
ROUTE

Generic Name: July 10 - Inhibits Indication: CNS: insomnia, - Assess lung sounds,
Doxofylline - 200mg/tab phosphodiesterase - For the treatment of irritability pulse and blood
- TID activities. COPD, bronchial pressure before
Brand Name: - Via NGT However, asthma and CV: tachycardia, administration and
Ansimar differently from pulmonary disease extra-systole during peak of
theophylline, with spastic medication.
Classification: doxofylline bronchial Resp: tachypnea - Observe for
Bronchodilator appears to have component. paradoxical
decreased GI: nausea, bronchospasm
affinities towards Contraindication: vomiting epigastric (wheezing). If
adenosine A1 and - Contraindicated in pain conditions occur
Aa2 receptors individuals who have withhold medication
which may shown and notify physician of
account for the hypersensitivity to its other health care
better safety components. professional
profile of the drug. - Contraindicated in immediately.
patients with acute - Monitor pulmonary
myocardial infarction function test before
and hypotension initiating therapy and
periodically during
therapy to determine
effectiveness of
medication.
DOSAGE,
NAME OF MECHANISM OF INDICATION AND NURSING
FREQ., SIDE EFFECTS
DRUG ACTION CONTRAINDICATION RESPONSIBILITIES
ROUTE

Generic Name: June 10 - Binds to an Indication: CNS: headache - Assess patient


Pantropazole - 40mg enzyme in the - Erosive esophagitis routinely for epigastric
- OD presence of acidic associated with GI: abdominal pain, or abdominal pain and
Brand Name: - IV gastric pH, GERD. Decreased diarrhea, flatulence. for frank or occult
Pantoloc preventing the relapse rates of blood in stool, emesis,
Shifted final transport of daytime and Endo: or gastric aspirate.
Classification: hydrogen ions into nighttime heartburn hyperglycemia
Proton-pump June 12 the gastric lumen. symptoms on Lab Test Considerations:
Inhibitor - 40mg/tab patients with GERD. - May cause abnormal
- OD Therapeutic Effects: - Pathologic liver function test,
- Via NGT - Diminished associated hyper- including increase in
accumulation of secretory conditions. AST, ALT, alkaline
acid in the gastric phosphatase, and
lumen, with Contraindication: bilirubin.
lessened acid - Hypersensitivity
reflux. Healing of
duodenal ulcers
and esophagitis.
Decreased acid
secretion in hyper-
secretory
conditions.
DOSAGE,
NAME OF MECHANISM OF INDICATION AND NURSING
FREQ., SIDE EFFECTS
DRUG ACTION CONTRAINDICATION RESPONSIBILITIES
ROUTE

Generic Name: July 10 Piperacillin Indication: CNS: seizures (high - Assess patient for
Piperacillin - 4.5mg - Binds to bacterial Community acquired doses), confusion, infection (Vital signs;
Tazobactam - Q8 cell wall and nosocomial dizziness, appearance of wound,
- IV membrane, pneumonia caused by headache, sputum, urine, and
Brand Name: - ANST (-) causing cell death. piperacillin-resistant, insomnia, lethargy. stool; WBC at
Zosyn Spectrum is beta-lactamase- beginning of and
July 17 extended producing bacteria. GI: diarrhea, during therapy.
Classification: - D/C compared with constipation, - Obtain specimens for
Anti-infective other penicillins. Contraindication: nausea, vomiting. culture and sensitivity
- Hypersensitivity to prior to initiating
Tazobactam penicillins, beta- Derm: rashes, therapy. First dose
- Inhibits beta- lactams, urticarial may be given before
lactamase, an cephalosporins, or receiving results.
enzyme that can Tazobactam Hemat: bleeding,
destroy leukopenia, Lab Test Consideration:
penicillins. neutropenia, - Evaluate renal and
thrombocytopenia. hepatic function, CBC,
Therapeutic Effects: serum potassium, and
Death of susceptible Local: pain, bleeding times prior to
bacteria. phlebitis at IV site. and routinely during
therapy.
- May cause increase in
BUN, creatinine, AST,
ALT, serum bilirubin,
alkaline phosphatase,
and LDH.
DOSAGE,
NAME OF MECHANISM OF INDICATION AND NURSING
FREQ., SIDE EFFECTS
DRUG ACTION CONTRAINDICATION RESPONSIBILITIES
ROUTE

Generic Name July 12 - Blocks stimulation Indication CNS: dizziness, - Monitor blood pressure
Carvedilol - 6.5mg/tab of beta1 - Hypertension fatigue, weakness, and pulse frequently
(myocardial) and anxiety, depression, during dose adjustment
Brand Name - BID beta2 (pulmonary, Contraindication drowsiness, period and periodically
Coreg - Via NGT vascular, and - History of serious insomnia, memory during therapy.
uterine) hypersensitivity loss, mental status - Assess for orthostatic
Classification adrenergic reaction (Steve- changes, hypotension when
Antihypertensive receptor sites. Johnson syndrome, nervousness, assisting patient up
beta blocker Also has alpha1 angioedema, nightmares. from supine position.
blocking activity, anaphylaxis); - Monitor intake and
which may result Bradycardia, heart EENT: blurred output ratios and daily
in orthostatic block or sick sinus vision, dry eyes, and weight. Assess patient
hypotension. syndrome (unless a nasal stuffiness. routinely for evidence
pacemaker is in of fluid overload
Therapeutic Effects: place); Resp:
- Decreased heart uncompensated bronchospasm, Lab Test Consideration:
rate and blood CHF requiring IV wheezing. - May cause increase in
pressure. inotropic agents BUN, serum
Improved cardiac (wean before starting CV: Bradycardia, lipoprotein, potassium,
output, slowing of carvedilol); Severe CHF, pulmonary triglyceride, and uric
the progression of hepatic impairment; edema acid levels.
CHF and Asthma or other
decreased risk of bronchospastic GI: diarrhea,
death. disorder. constipation,
nausea.
DOSAGE,
NAME OF MECHANISM OF INDICATION AND NURSING
FREQ., SIDE EFFECTS
DRUG ACTION CONTRAINDICATION RESPONSIBILITIES
ROUTE

Generic Name July 14 - Inhibit bacterial Indication CNS: seizures, - Assess for infection
Levofloxacin - 750mg/tab DNA synthesis by - Treatment of the dizziness, (vital signs; sputum,
- OD inhibiting DNA following bacterial headache, WBC) prior to and
Brand Name - Via NGT gyrase. infections: insomnia, acute during therapy.
Levaquin Respiratory tract psychoses, - Obtain specimen for
Therapeutic Effect: infection including agitation, confusion, culture and sensitivity
Classification - Death of acute sinusitis, acute drowsiness. before initiating
Anti-infective susceptible exacerbations of therapy. First dose
bacteria chronic bronchitis, CV: arrhythmias, QT may be given before
and pneumonia. prolongation, receiving results.
vasodilation. - Observe signs and
Contraindication symptoms of
- Hypersensitivity GI: diarrhea, anaphylaxis (rash,
nausea, abdominal pruritus, laryngeal
pain, vomiting. edema, wheezing).
Discontinue drug and
notify physician
immediately. Keep
epinephrine, an
antihistamine, and
resuscitation
equipment close by in
case of an
anaphylactic reaction.

Lab Test Considerations:


- May cause increase in
serum AST, ALT LDH,
bilirubin, and alkaline
phosphatase.
DOSAGE,
MECHANISM OF INDICATION AND SIDE NURSING
NAME OF DRUG FREQ.,
ACTION CONTRAINDICATION EFFECTS RESPONSIBILITIES
ROUTE

Generic Name July 15 - Maintain acid- Indication CNS: confusion, - Assess for signs and
Potassium Chloride - 1tab base balance, - Treatment/prevention restlessness, symptoms of
- TID isotonicity, and of potassium weakness hypokalemia
Brand Name - Via NGT electrophysiologic depletion (weakness, fatigue,
K-Lyte balance of the CV: arrhythmias U wave on ECG,
cell. Contraindication arrhythmias,
Classification - Hyperkalemia GI: abdominal polyuria, polydipsia)
Mineral and electrolyte Therapeutic Effects: pain, diarrhea, and hyperkalemia
replacements/supplement - Replacement flatulence, - Monitor pulse, blood
- Prevention of nausea, vomiting pressure, and ECG
deficiency periodically during IV
therapy.

Lab Test Consideration


- Monitor serum
potassium before
and periodically
during therapy.
DOSAGE,
NAME OF MECHANISM OF INDICATION AND NURSING
FREQ., SIDE EFFECTS
DRUG ACTION CONTRAINDICATION RESPONSIBILITIES
ROUTE

Generic Name July 14 - Antagonizes the Indication CNS: suicidal - Assess lung sounds
Montelukast - 10mg/tab effects of - Prevention and thoughts, agitation, and respiratory
- OD leukotrienes, which chronic treatment of aggression, anxiety, function prior to and
Brand Name - Via NGT mediate the asthma. depression, fatigue, periodically during
Singulair following: Airway Management of hallucinations, therapy.
edema, Smooth seasonal allergic headache, - Monitor closely for
Classification muscle constriction, rhinitis. Prevention of insomnia, irritability, changes in behavior
Bronchodilators altered cellular exercise-induced restlessness, that cloud indicate the
activity. Result is bronchoconstriction tremor, weakness. emergence or
decreased in patients 15 yr. and worsening of
inflammatory older. EENT: nosebleed, depression or suicidal
process, which is thoughts.
part of asthma and Contraindication Resp: cough,
allergic rhinitis. - Hypersensitivity rhinorrhea Lab Test
Considerations:
Therapeutic Effects: GI: abdominal pain - May cause increase in
- Decreased AST and ALT
frequency and concentrations.
severity of acute
asthma attacks.
Decreased severity
of allergic rhinitis.
Decreased attacks
of exercise-induced
bronchoconstriction.
DOSAGE,
MECHANISM OF INDICATION AND NURSING
NAME OF DRUG FREQ., SIDE EFFECTS
ACTION CONTRAINDICATION RESPONSIBILITIES
ROUTE

Generic Name July 17 - Suppress Indication CNS: depression, - Monitor intake and
Methylprednisolone - 16mg/tab inflammation and - Asthma euphoria, output ratios and daily
- BID the normal headache, weights. Observe
Brand Name - PO immune Contraindication restlessness. patient for peripheral
Medixon response. - Active untreated edema, steady weight
infections EENT: cataracts gain, rale/crackles, or
Classification Therapeutic Effect: dyspnea.
Corticosteroids - Suppression of CV: hypertension
(intermediate- inflammation and Lab Test Consideration:
acting modification of the GI: peptic - Monitor serum
corticosteroids) normal immune ulceration, electrolytes and
response. anorexia, nausea, glucose. May cause
vomiting. hypokalemia.
Patient on prolonged
therapy should routinely
have CBC, serum
electrolytes, and serum
and urine glucose
evaluated.
DOSAGE,
NAME OF MECHANISM OF INDICATION AND NURSING
FREQ., SIDE EFFECTS
DRUG ACTION CONTRAINDICATION RESPONSIBILITIES
ROUTE

Generic Name July 10 - Inhibits protein Indication CNS: dizziness, - Assess patient for
Azithromycin - 500mg synthesis at the - Treatment of the seizures, infection (vital signs,
- OD level of the 50S following infectious drowsiness, fatigue, sputum and WBC)
Brand Name - IV bacterial due to susceptible headache - Obtain specimens for
Zithromax ribosome. organism: Upper culture and sensitivity
July 11 respiratory tract CV: chest pain, before initiating
Classification - Discontinued Therapeutic Effects: infections, including hypotension, therapy. First dose
Agents for - ANST + - Bacteriostatic streptococcal palpitations, QT may be given before
atypical action against pharyngitis, acute prolongation (rare). receiving results.
mycobacterium, susceptible bacterial
anti-infective bacteria. exacerbations of GI: abdominal pain, Lab Test
chronic bronchitis diarrhea, nausea, Considerations:
and tonsillitis; Lower cholestatic - May cause increase in
respiratory tract jaundice, melena serum bilirubin, AST,
infections, including ALT, LDH, and alkaline
bronchitis and Hemat: anemia, phosphatase
pneumonia. leukopenia concertation.
- Mat cause increase in
Contraindication: creatinine
- Hypersensitivity to phosphokinase,
azithromycin, potassium, BUN,
erythromycin, or serum creatinine.
other macrolide anti- - May occasionally cau
infectives. decrease in WBC and
platelet count.

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