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    Cut Off Point

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    firuzz1
    The document contains data on the sensitivity and specificity of two biomarkers, CK-MB and Troponin I, at different cutoff values for determining a positive test result. It includes a table with the cutoff values, sensitivity, and 1-specificity for each marker. It notes that some cutoff values result in ties between positive and negative actual states for the CK-MB marker. The smallest cutoff is set as the minimum observed test value minus 1, and the largest is the maximum observed value.

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    Cut Off Point

    Uploaded by

    firuzz1
    42 views8 pages
    The document contains data on the sensitivity and specificity of two biomarkers, CK-MB and Troponin I, at different cutoff values for determining a positive test result. It includes a table with the cutoff values, sensitivity, and 1-specificity for each marker. It notes that some cutoff values result in ties between positive and negative actual states for the CK-MB marker. The smallest cutoff is set as the minimum observed test value minus 1, and the largest is the maximum observed value.

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    vut off ptm

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    The document contains data on the sensitivity and specificity of two biomarkers, CK-MB and Troponin I, at different cutoff values for determining a positive test result. It includes a table with the cutoff values, sensitivity, and 1-specificity for each marker. It notes that some cutoff values result in ties between positive and negative actual states for the CK-MB marker. The smallest cutoff is set as the minimum observed test value minus 1, and the largest is the maximum observed value.

    Copyright:

    © All Rights Reserved
    Download as XLSX, PDF, TXT or read online from Scribd
    Download as xlsx, pdf, or txt
    42 views8 pages

    Cut Off Point

    Uploaded by

    firuzz1
    The document contains data on the sensitivity and specificity of two biomarkers, CK-MB and Troponin I, at different cutoff values for determining a positive test result. It includes a table with the cutoff values, sensitivity, and 1-specificity for each marker. It notes that some cutoff values result in ties between positive and negative actual states for the CK-MB marker. The smallest cutoff is set as the minimum observed test value minus 1, and the largest is the maximum observed value.

    Copyright:

    © All Rights Reserved
    Download as XLSX, PDF, TXT or read online from Scribd
    Download as xlsx, pdf, or txt
    of 8

    Coordinates of the Curve

    Test Result VaKadar CK-MB (U/L)

    Positive if
    Greater
    Than or 1-
    No Equal Toa Sensitivity Spesifisitas Specificity
    1 11.900 1.000 0.000 1.000

    2 15.150 1.000 0.040 .960 1.200


    3 17.600 1.000 0.080 .920

    4 18.200 1.000 0.120 .880

    5 18.800 1.000 0.160 .840

    6 19.500 1.000 0.200 .800 1.000


    7 20.050 .960 0.200 .800

    8 20.135 .960 0.240 .760

    9 20.635 .960 0.280 .720

    10 21.250 .960 0.320 .680 0.800


    11 21.750 .960 0.360 .640

    12 22.250 .960 0.400 .600

    13 22.700 .960 0.440 .560

    14 23.050 .960 0.480 .520


    0.600
    15 23.150 .960 0.520 .480

    16 23.350 .960 0.560 .440

    17 23.750 .960 0.600 .400

    18 24.100 .920 0.600 .400


    0.400
    19 24.250 .880 0.600 .400

    20 24.650 .880 0.640 .360

    21 25.400 .880 0.680 .320

    22 25.850 .880 0.720 .280


    0.200
    23 26.000 .840 0.720 .280

    24 26.150 .800 0.760 .240

    25 26.250 .800 0.800 .200

    26 26.500 .760 0.800 .200


    0.000
    27 26.795 .760 0.840 .160
    1 2 3 4 5 6 7 8 9 10 11 12 1
    28 26.895 .760 0.880 .120

    29 26.950 .760 0.920 .080

    30 27.050 .680 0.920 .080

    31 27.550 .640 1.000 0.000

    32 28.500 .560 1.000 0.000

    33 29.100 .440 1.000 0.000

    34 29.500 .400 1.000 0.000

    35 29.850 .360 1.000 0.000

    36 29.950 .320 1.000 0.000


    37 30.300 .200 1.000 0.000

    38 31.400 .160 1.000 0.000

    39 32.450 .120 1.000 0.000

    40 33.050 .080 1.000 0.000

    41 34.500 .040 1.000 0.000

    42 36.600 0.000 1.000 0.000


    Col
    Col

    3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42
    Column C
    Column D

    6 37 38 39 40 41 42
    Coordinates of the Curve
    Test Result Kadar Troponin I (ng/ml)

    Positive if
    Greater
    Than or Spesifisita
    No Equal Toa Sensitivity s 1 - Specificity 1.200
    1 0.0000 1.000 0.000 1.000

    2 .1150 1.000 0.080 .920

    3 .1250 1.000 0.120 .880


    1.000
    4 .1400 1.000 0.160 .840

    5 .1550 1.000 0.320 .680

    6 .1650 1.000 0.400 .600


    0.800
    7 .1750 1.000 0.520 .480

    8 .1850 1.000 0.640 .360

    9 .1950 .880 0.760 .240


    0.600
    10 .2100 .800 0.840 .160
    11 .2250 .760 0.880 .120
    12 .2350 .720 0.920 .080
    13 .2450 .720 0.960 .040 0.400
    14 .2550 .640 0.960 .040
    15 .2650 .520 1.000 0.000
    16 .2750 .480 1.000 0.000 0.200
    17 .2850 .400 1.000 0.000
    18 .2950 .280 1.000 0.000
    19 .3050 .200 1.000 0.000
    0.000
    20 .3150 .160 1.000 0.000 1 2 3 4 5 6 7 8 9 10 11
    21 .3350 .080 1.000 0.000
    22 .3550 .040 1.000 0.000

    23 1.0000 0.000 1.000 0.000


    The test result variable(s): Kadar Troponin I (ng/ml)
    has at least one tie between the positive actual state
    a. The smallest cutoff value is the minimum observed
    test value minus 1, and the largest cutoff value is the
    Column C
    Column D

    6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
    Positive if
    Greater
    Than or 1-
    Equal Toa Sensitivity Specificity
    11.900 1.000 1.000
    15.150 1.000 .960
    17.600 1.000 .920
    18.200 1.000 .880
    18.800 1.000 .840
    19.500 1.000 .800
    20.050 .960 .800
    20.135 .960 .760
    20.635 .960 .720
    21.250 .960 .680
    21.750 .960 .640
    22.250 .960 .600
    22.700 .960 .560
    23.050 .960 .520
    23.150 .960 .480
    23.350 .960 .440
    23.750 .960 .400
    24.100 .920 .400
    24.250 .880 .400
    24.650 .880 .360
    25.400 .880 .320
    25.850 .880 .280
    26.000 .840 .280
    26.150 .800 .240
    26.250 .800 .200
    26.500 .760 .200
    26.795 .760 .160
    26.895 .760 .120
    26.950 .760 .080
    27.050 .680 .080
    27.550 .640 0.000
    28.500 .560 0.000
    29.100 .440 0.000
    29.500 .400 0.000
    29.850 .360 0.000
    29.950 .320 0.000
    30.300 .200 0.000
    31.400 .160 0.000
    32.450 .120 0.000
    33.050 .080 0.000
    34.500 .040 0.000
    36.600 0.000 0.000
    The test result variable(s): Kadar
    CK-MB (U/L) has at least one tie
    The smallest cutoff value is the
    minimum observed test value

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