MSC Chemistry For Colleges 2018-19
MSC Chemistry For Colleges 2018-19
MSC Chemistry For Colleges 2018-19
SYLLABUS
FOR
Scheme of Courses
Semester-IV
SECTION-A
1. Symmetry (10Hrs.)
Symmetry elements, symmetry operations and their matrix representation, group postulates and
types, multiplication tables, point group determination, determination of reducible and
irreducible representations, character tables, construction of character tables for C2v, C3v (non-
abelian group), use of symmetry in obtaining symmetry of orbitals in molecules, use of character
table to determine which metal orbitals are used in σ and π bond formation in octahedral,
tetrahedral and square planar transition metal complexes, qualitative splitting of s, p, d, f orbitals
in octahedral, tetrahedral and square planar fields using character tables and without the use of
character tables.
SECTION-B
2. Molecular Orbital Theory for Metal Complexes (5 Hrs.):
Recapitulaltions, ligands symmetry orbitals and metal orbitals involved in molecular orbitals
formation in octahderal complexes, MOEL diagrams for octahedral tetrahedral and square planar
complexes showing σ and π bonding in transition metal complexes.
3. Interelectronic Repulsions (5 Hrs.):
Spin-spin, orbital-orbital and spin orbital coupling, LS and jj coupling schemes, determination of
all the spectroscopic terms of pn, dn ions, determination of the ground state terms for pn, dn, fn
ions using L.S. scheme, determination of total degeneracy of terms, order of interelectronic
repulsions and crystal field strength in various fields, two type of electron repulsion parameters,
spin orbit coupling parameters (λ) energy separation between different j states, The effect of
octahedral and tetrahedral fields on S, P, D and F terms (with help of the character table),
splitting patterns of and G, H and I terms.
SECTION-C
4. Free Ions in Medium and Strong Crystal Fields (5 Hrs.):
Strong field configurations, transition from weak to strong crystal fields, evaluation of strong
crystal field terms of d2 configuration in octahedral and tetrahedral crystal fields (using group
theory), construction of the correlation energy level diagrams of d2 configuration in octrahedral
field, study of energy level diagrams for higher configurations, selection rules of electronic
transitions in transition metal complexes, their proof using group theory, relaxation of the
selection rule in centrosymmetric and non-centrosymmetric molecules, Orgel diagrams, Tanabe
Sugano diagrams
4
M.Sc. (Chemistry) (Semester-I) (FOR COLLEGES)
Recommended Books:
1. F.A. Cotton, Chemical Application of Group Theory, Wiley Eastern.
2. G. L. Miessler, D. A. Tarr, Inorganic Chemistry, 3rd edition, Pearson Education.
3. B.N. Figgis, Introduction to Ligand Field, Wiley Eastern.
4. A.B.P. Lever, Inorganic Electronic Spectroscopy, Elsevier.
5. A. Earnshaw, Introduction to Magnetochemistry, Academic Press.
6. J.E. Huheey, Inorganic Chemistry Principles of Structure and Reactivity, Harper
Interscience.
7. R.S. Drago, Physical Method in Chemistry, W.B. Saunders Company.
8. F.A. Cotton and G. Wilkinson, Advanced Inorganic Chemistry, Wiley Inter-science.
5
M.Sc. (Chemistry) (Semester-I) (FOR COLLEGES)
COURSE II
Organic Reaction Mechanism- I
45 Hrs Max. Marks: 50
Time: 3 hrs.
SECTION-A
1. Nature of Bonding in Organic Reactions: (4 Hrs.)
Aromaticity in Benzenoid and non-benzenoid compounds. Huckel’ Rule, Alternant and non-
alternant hydrocarbons. Energy levels of π(pi) molecular orbitals in simple systems. Annulenes,
Antiaromaticity, Homoaromaticity, PMO approach.
2. Stereochemistry : (8 Hrs.)
Elements of symmetry, chirality, molecules with more than one chiral center. Threo and erythro
isomers, methods of resolution, optical purity. Prochirality – enantiotopic and diastereotopic
atoms, groups and faces. Stereospecific and stereoselective synthesis. Asymmetric synthesis.
Optical activity in absence of chiral carbon (Biphenyls, Allenes, Spiranes). Chirality due to
helical shape.
SECTION-B
3. Reaction Mechanism, Structure and Reactivity: (8 Hrs.)
Types of mechanisms, types of reactions, thermodynamic and kinetic requirements, Kinetic and
thermodynamic control in product formation. Transition states and reaction intermediates,
Isotope effects, Hard and Soft Acid Base concept, Study of reactive intermediates – Types of
intermediates, isolation and detection of intermediates (including use of spectral techniques),
trapping of intermediates.
SECTION-D
7. Aromatic Electrophilic Substitution: (5 Hrs.)
The arenium ion mechanism, orientation and reactivity in mono substituted and di substituted
aromatics. Energy profile diagrams. The ortho/para ratio, ipso attack, orientation in other ring
systems. Quantitative treatment of reactivity in substrates and electrophiles. Diazo coupling,
Vilsmeir reaction, Gattermann-Koch reaction, Pechmann reaction, Houben – Hoesch reaction,
Fries rearangement.
8. Aromatic Nucleophilic Substitution: (5 Hrs.)
SNAr, SN1, benzyne and SRN1 mechanisms. Reactivity effect of substrate structure, leaving
group and nucleophile. The von Richter, Sommelet-Hauser, and Smiles rearrangements.
Books Recommended:
1. Stereochemistry - Eliel
SECTION-A
SECTION-B
SECTION-C
Partition functions(Hrs.10)
Translational, rotational, vibrational and electronic partition function, calculation of
thermodynamic properties in terms of partition functions. Application of partition functions.
Books Suggested:
1. I F Nash: Elements of classical and statistical thermodynamics
2. Lee Bot: Irreversible thermodynamics
3. Thermodynamics of Biological Processes, D. Jou and J.E. Lee Bot
4. I Prigogine: Introduction to thermodynamics of irreversible processes
5. T L Hill: Introduction to statistical thermodynamics.
9
M.Sc. (Chemistry) (Semester-I) (FOR COLLEGES)
COURSE IV
SPECTROSCOPY – A: Techniques in Structure Elucidation of Organic Compounds
SECTION-A
SECTION-B
SECTION-D
Books Recommended:
Recommended Books:
1. K.V. Raman, Computers in Chemistry, Tata McGraw Hill.
2. Mullish Cooper, The spirit of c, An Introduction to Modern Programming.
13
M.Sc. (Chemistry) (Semester-I) (FOR COLLEGES)
COURSE - VI
I. Oxidation-Reduction Titrations
1. Standardization with sodium oxalate of KMnO4 and determination of Ca2+ ion.
2. Standardization of ceric sulphate with Mohr’s salt and determination of NO 3-1 and
C2O4-2 ions.
3. Standardization of K2Cr2O7 with Fe2+ and determination of Fe3+ (Ferric alum)
4. Standardization of hypo solution with potassium iodate / K 2Cr2O7 and determination of
available Cl2 in bleaching powder, Sb3+ and Cu2+.
5. Determination of hydrazine with KIO3 titration.
II. Precipitation Titrations
1. AgNO3 standardization by Mohr’s method by using adsorption indicator.
2. Volhard’s method for Cl- determination.
3. Determination of ammonium / potassium thiocyanate.
III. Complexometric Titrations
1. Determination of Mg2+ and Mn2+ in a mixture using fluoride ion as a demasking agent.
2. Determination of Ni2+ (back titration).
3. Determination of Ca2+ (by substitution method).
IV. Gravimetric Analysis
1. Determination of Ba2+ as its chromate.
2. Estimation of lead as its lead molybdate.
3. Estimation of chromium (III) as its lead chromate.
4. Estimation of Cu2+ using Ammonium/ Sodium thiocyanate.
Unit – I
1. Purification and Characterization of Organic Compounds, the student is expected to
carry out the experiments of purification (fractional crystallization, fractional distillation,
chromatography) separation, purification and identification of the compounds of binary
organic mixture (liquid-liquid, liquid-solid and solid-solid), using chemical analysis and IR
and PMR spectral data. The student should also check the purity of the separated components
on TLC plates.
2. To carry out the analysis of common analgesic drugs by thin layer chromatography,
Acetaminophen, Aspirin, caffeine, phenacetin, salicylamide. (Learn to check purity of the
given samples and completion of the chemical reactions).
Unit – 2
Organic Synthesis and Extraction of Organic Compounds from Natural Sources. The
student is expected to carry out 4 to 6 organic preparations (usually involving not more than two
steps), some of the illustrative experiments are listed below:-
1. Extraction of Caffeine from tea leaves
(Ref. Experiment Organic Chemistry, (H. Dupont Durst, George W. Gokel, P 464 McGraw
Hill Book Co., New York).
Student would be asked to purity crude sample, check the purity on a TLC single spot and get
the NMR scanned and interpret (Three methyl singlets and I methane singlet).
2. Isolation of casein from milk (try some typical colour reactions proteins).
3. Synthesis of 2-phenyllndole-Fischer Indole Synthesis. Book 1, p. 852
Aim: To Study condensation and cyclization reactions.
4. Synthesis of 3-nitrobenzoic from benzoic acid (Rf. Ibid., p.245-247 and 443-448).
Aim: To demonstrate the process of meta nitration, esterification and saponification of an
ester. Make a comparative study of IR and PMR spectra of benzoic acid, methyl benzoate,
methyl 3-nitrobenzoate.
5. Cannizaro’s reaction of 4-chlorobenzaldehyde.. Book 1, p 760
Aim: To demonstrate technique of isolation of two products from the reaction mixture and
the procedure of intermolecular hydride transfer.
Make a comparative study of IR and PMR spectra of 4 chlorobenzadehyde, 4-chlorobenzoic
acid 4-chlorobenzyl alcohol.
6. Synthesis of 1,3,5-Tribromobenzene from aniline.
Aim: To demonstrate: Bromination, Diazotization and Reduction.
45 Hrs.
Time: 3 Hrs. Max. Marks: 50
SECTION-A
(Hrs. 10)
Organometallics
Energy polarity and reactivity of M-C bond, Stability of Main group organometallics: Methods
of preparation in perspective-organolithium compounds: structure and bonding & reaction-
carbolithiatic organometallics of group 2 and 12 e.g. Mg and Zn, Cd and Hg: Preparation and
structure of organoaluminium compounds, Technical applications of Tris (alkyl) aluminium
compounds. 2- ligands: olefenic and acetylenic complexes, chelating olefenic ligands –
synthesis and structure. 2 – ligands: Allylic and 4– complexes of cyclopentadiene.
SECTION-B
(Hrs. 10)
Synthesis and structure. –ligands: Butadiene, cyclobutadiene, heterocyclic pentadiene (S, Se,
4
A-(Hrs.5)
Homogeneous hydrogenation of unsaturated compounds, reversible cis-dihydrocatalysis,
monohydrido compounds, asymmetrical hydrogenation, hydrosilation of unsaturated compounds,
hydrocyanation of alkenes, alkane metathesis, Ziegler-Natta polymerization of ethylene and
propylene, water gas shift reaction, acetic acid synthesis by carbonyls, Oxopalladation reactions.
Organometallic Reagents in Organic synthesis.
16
M.Sc. (Chemistry) (Semester-II) (FOR COLLEGES)
SECTION-C
B-(Hrs.5)
The role of metal ions in the hydrolysis of amino acid esters, peptides, and amides Molecular
orbital concept of role of metal ions participation, Modified aldol condensation, Imine formation,
Template and Macrocyclic effect in detail.
SECTION-D
Books Recommended:
1. C. Elschenbroich and A. Salzer, Organometallics: A Concise Introduction, 2nd Ed., VCH
1992.
2. J.E. Huheey, Inorganic Chemistry Principles of Structure and Reactivity, Harper
Interscience.
3. F.A. Cotton and G. Wilkinson, Advanced Inorganic Chemistry, Ed. V & VI.Wiley
Inter-science.
4. G. L. Miessler, D. A. Tarr, Inorganic Chemistry, 3rd edition, Pearson Education
17
M.Sc. (Chemistry) (Semester-II) (FOR COLLEGES)
COURSE-IX
Organic Reaction Mechanism - II
45 hrs. Max. Marks: 50
Time: 3 hrs.
SECTION-A
SECTION-D
7. Oxidation (5 Hrs)
Introduction. Different oxidative processes. Hydrocarbons - alkenes, aromatic rings, saturated C-
H groups (activated and unactivated). Alcohols, diols, aldehydes, ketones, ketals and carboxylic
acids. Amines, hydrazines, and sulphides. Oxidations with ruthenium tetraoxide, iodobenzene
diacetate and thallium(III) nitrate.
8. Reduction (5 Hrs)
Introduction . Different reductive processes. Hydrocarbons - alkanes, alkenes, alkynes and
aromatic rings. Carbonyl compounds – aldehydes, ketones, acids and their derivatives. Epoxides.
Nitro, nitroso, azo and oxime groups. Hydrogenolysis.
Books Recommended:
5. Hand Book of Reagents for Organic Synthesis - Oxidizing and Reducing Reagents. S. D.
SECTION-A
9 Hrs.
1. Quantum Theory: Introduction and Principles :
Black body radiations, planck’s radiation law, photoelectric effect, Compton effect, De- Broglie
hypothesis, the Heisenberg’s uncertainty principle, Rydberg relation for explaining atomic
spectrum of hydrogen. Bohr’s Theory and its limitation solution of classical wave equation by
separation of variables method.
SECTION-B
9Hrs.
2. Operators and observations, normal and orthogonal functions, hermitian and unitary operators,
introduction to differentiation and integration, Eigen value equation. Hamiltonian operator,
interpretation of wave function, postulates of quantum mechanics.
SECTION-C
3. Applications of Quantum Postulates (8 Hrs.)
Solution of particle in one and three dimensional box, degeneracy, the linear harmonic oscillator,
rigid rotators, quantization of vibrational and rotational energy levels, hydrogen and hydrogen
like atoms.
4. Angular Momentum (5 Hrs.)
Commutative laws, need of polar coordinates, transformation of Cartesian coordinate into polar
coordinate, angular momentum of one particle system, orbital angular momentum, the ladder
operator method for angular momentum, spin angular momentum and their relations
SECTION-D
5. General Orbital Theory of Conjugated Systems (8 Hrs.)
Chemical bonding, linear combination of atomic orbital, overlap integral, coulomb’s
integral, bond order, charge density calculations for ethylene, allyl system, butadiene
system, cyclo butadiene cyclo propenyl system.
6. The Approximate Methods (6 Hrs.):
Need for approximation methods, Perturbation and Variation methods and their application to
Helium atom.
20
M.Sc. (Chemistry) (Semester-II) (FOR COLLEGES)
Books Suggested:
45 Hrs.
Time: 3 Hrs. Max. Marks: 50
SECTION-A
Books Recommended:
1. K.P. Purcell and J. V. Kotz: Inorganic Chemistry W.B. Saunders Co. London, (1977).
3. F.A. Cotton & Wilkinson: Inorganic Chemistry V & VI Ed. Willy Eastern – (1999).
4. J.E. Huheey: Inorganic Chemistry III & IV Ed. Pearson Education Asia – (2002).
23
M.Sc. (Chemistry) (Semester-II) (FOR COLLEGES)
Course–XII
SECTION-A
Symmetry and Point Groups: (Book 2) (6 Hrs.)
Definition of symmetry, symmetry elements, determination of point groups, introduction to use
of character table in determining irreducible representation and symmetry of the atomic orbitals.
SECTION-B
Vibration and Rotation Spectroscopy: Infrared, Raman and Microwave (Book 2) (17 Hrs.)
Books Recommended:
1. E.A.V Ebsworth; W.H Renkin; Cradock, Structure Methods in Inorganic Chemistry.
2. R.S Drago, Physical Methods for Chemists (Ist and IInd Edition).
3. C.N Banwell, Fundamentals of Molecular Spectroscopy.
4. S. Walker and H. Straugh an Spectroscopy, Vol.I.
5. J.E. Wertz & J.R. Bolton, Electron Spin Resonance (p.49-65).
6. N.N. Greenwood & T.C Tibb, Mossbauer Spectroscopy.
7. K. Nakamoto, Infrared Spectra of Inorganic and co-ordination Compounds.
25
M.Sc. (Chemistry) (Semester-II) (FOR COLLEGES)
Course – XIII
MATHEMATICS FOR CHEMISTS
(For Medical Students)
30 hrs.
Time: 2 Hrs. Max. Marks: 25
Section-A
Trigonometry and Determinants:
Definition of sin, cos, tan, cot, sec, cosec functions with the help of unit circle, values of sin x,
cos x for x = 0, /6, /3, /2. Trigonometric identities (without proofs) and their applications.
Definition and expansion properties of determinants, product of two determinants of 3rd order.
Section-B
Matrices:
Introduction to various forms of Matrices, row, column, diagonal unit, Submatrix, square, equal
matrices, null, symmetric and skew symmetric matrices, transpose of a matrix, adjoint and
inverse of matrices. Addition, multiplication, characteristic equation of a matrix, statement of
Cayley Hamilton theorem. Rank of matrix, condition of consistency of a system of linear
equations. Eigen vectors and Eigen values ofmatrices.
Section-C
Differential Calculus
Differentiation of standard functions, theorems relating to the derivative of the sum, difference,
product and quotient of functions (without proofs), derivative of trigonometric functions, inverse
trigonometric functions, logarithmic functions and exponential functions, differentiation of
implict functions, logarithmic differentiation.
Section-D
Integral Calculus
Integration as an inverse of differentiation, summation, area under a curve, indefinite integrals of
standard forms, method of substitution, method of partial fractions, integration by parts,
definite integrals, reduction formulae, definite integrals as limit of a sum and geometrical
interpretation.
Books Recommended:
1. Santi Narayan & P.K. Mittal – Differential Calculus.
2. Santi Narayan & P.K. Mittal - Integral Calculus.
3. B.S. Grewal – Higher Engineering Mathematics.
4. Joseph B. Dence – Mathematical Techniques in Chemistry.
5. Margenau and Murphy, the Mathematics of Physics and Chemistry.
6. B.L. Moncha and H.R. Choudhary – A Text Book of Engineering Mathematics.
26
M.Sc. (Chemistry) (Semester-II) (FOR COLLEGES)
Course – XIII
BIOLOGY FOR CHEMISTS
(For Non-Medical Students)
30 hrs.
Time: 2 Hrs. Max. Marks: 25
SECTION-B
(7 hrs.)
3. Tissues, organs and organ systems: Animal tissues; epithelial tissues, connective tissues,
muscle tissue, nervous tissue and neoplasias; plant tissue: maristematic tissue, permanent
tissues.
SECTION-C
Genetics (8 hrs.)
4. The basic principle of heredity: Mendals law, monohybrid cross, dihybrid cross.
5. DNA – Double halix structure and replication.
6. Genes expression: Transcription and translation, genetic code.
SECTION-D
Book Recommended:
Hrs: 60
Max. Marks: 75
Books Recommended:
1. An Introduction to Modern Experimental Organic Chemistry, R. M. Roberts, J. C. Gilbert,
L.B.Rodewald and A. S. Wingrove Holt, Ranehart and Winston Inc. New York.
2. Introduction to Organic Laboratory Techniques – A Contemporary Approach. D. L. Pavia,
G. M. Lampmana and G. S. Kriz, W. B. Saunders Company, 1976.
3. Laboratory Experiments in Organic Chemistry, R. Adams, J. R. Johnson and C. F. Wilcox.
The Macmillan Limited, London.
4. Text Book of Practical Organic Chemistry, A. I. Vogel.
28
M.Sc. (Chemistry) (Semester-II) (FOR COLLEGES)
COURSE-XV
Physical Chemistry (Practical)
Section-B: 12 short answer type questions are to be set. Eight questions are to be attempted.
Maximum length of the answer can be upto 2 pages. In papers having 50 marks, each question
will be of three marks, total weightage being 24 marks.
Section-C: Four questions are to be set. Two questions are to be attempted. In this section there
will be descriptive questions, derivations, synthesis, structure and bonding, reactions and
conversions etc. Maximum length of answer can be upto 5 pages. In papers having 50 marks,
each question will be of 8 marks, total weightage being 16 marks.
Metal Ions in Biological Systems- Essential and trace elements, periodic survey of essential and
trace elements, biological importance and relative abundance, Na+/ K+ ion pump.
Transport and Storage of Dioxygen- Oxygen carriers-Hb and Mb: Structure and mechanism of
their function, cooperativity, inhibition and poisoning by ligands and metal ions, hemocyanins
and hemerythrin, model complexes of iron, cobalt and copper.
Bioenergetics and ATP Cycle- Process concept to phosphate hydrolysis, Nucleotide transfer-
DNA polymerase, phosphate transfer pyruvate kinase, phosphoglucomutase, created kinase,
ATPase. Photosynthesis and respiration – chlorophyll : structure, function and its synthetic
model.
Bioredox Agents and Mechanism- Enzymes and their functioning, Vitamin B12 coenzyme, its
function and application in organic syntheses, intake of alcohol and its remedy.
Biochemistry of Iron- Availability of iron, competition for iron, iron toxicity and nutrition.
Electron Transfer in Biology- Cytochromes-structure and function, CN- and CO poisoning,
Ferredoxin and rubredoxim.
Nitrogenase- Biological N2 fixation, molybdenum nitrogenase, spectroscopic and other
evidence, other nitrogenases model systems.
Metal Storage, Transport- Ferritin, transferring and siderophores.
Metalloenzymes- Zinc enzymes-carboxypeptidase and carbonic anhydrase, Copper enzymes-
superoxide dismutase.
Calcium in Biology- Calcium in living cell, transport and regulation, molecular aspects of
intramolecular processes,
Metals in Medicine- Metal deficiency and disease, toxic effects of antibiotics and related
compounds, chelate therapy.
30
M.Sc. (Chemistry) (Semester-III) (FOR COLLEGES)
Books Recommended:
COURSE-XVII
ORGANIC SYNTHESIS
45 hrs.
Time: 3 Hrs. Max. Marks 50
Book Recommended
1. Supramolecular Chemistry, Jonathan W. Steed, Jerry L. Atwood, John Wiley & Sons
33
M.Sc. (Chemistry) (Semester-III) (FOR COLLEGES)
COURSE-XVIII
SURFACE AND POLYMER CHEMISTRY
Books Suggested:
1. Physical Chemistry, P. W. Atkins.
2. Textbook of polymer science, F. W. Billmeyer Jr. Wiley.
3. Polymer science, V. R. Gowariker, N. V. Viswanathan and J. Sreedhar, Wiley-Eastern.
34
M.Sc. (Chemistry) (Semester-III) (FOR COLLEGES)
Course-XIX
Electrochemistry and Chemical Dynamics
Books Recommended:
1. Chemical Kinetics, K. J. Laddler, McGraw-Hill
2. Modern Electrochemistry Vol.1,2,3, J. Bochris and A.K.N. Reddy
3. Fundamentals of electrochemistry; P. Monk
4. Principles of Instrumental Analysis; Skoog, West; Saundres Publications
35
M.Sc. (Chemistry) (Semester-III) (FOR COLLEGES)
COURSE-XX
PHOTOCHEMISTRY AND PERICYCLIC REACTIONS
45 Hrs
Time: 3 Hrs. Max. Marks 50
Electrocyclic reactions – controtatory and disrotatory motions, 4n, 4n+2, allylsystems secondary
effects. Cycloadditions – antrafacial and suprafacial additions, notation of cylcoadditions (4n)
and (4n+2) systems with a greater emphasis on (2+2) and (4+2) cycloaddition-stereochemical
effects and effects of substituents on the rates of cycloadditions, 1,3-dipolar cyclo-additions and
cheleotropic reactions.
2. Photochemistry
(i) Photochemical Reactions (4 Hrs.)
Interaction of electromagnetic radiation with matter, types of excitations, fate of excited
molecule, quantum yield, transfer of excitation energy, actinometry.
Books Recommended:
1. Organic Photochemistry – Chapman and Depuy.
2. Organic Photochemistry – W.H. Horsepool.
3. Photochemistry of Excited States – J.D.Goyle.
37
M.Sc. (Chemistry) (Semester-III) (FOR COLLEGES)
COURSE-XXI
Inorganic Chemistry (Practical)
(Preparations)
Time: 6 Hours
Course Hrs. 60 Max. Marks: 50
(Any 8 Complexes.)
1. Preparation of Co. (acac)3, its characterization using NMR, IR, UV-Vis and analysis of
Cobalt. (ref. J. Chem. Edu., 1980, 57, 7, 525)
2. Preparation of Co. (acac-NO2)3, its characterization using NMR, IR, UV-Vis and analysis
of Cobalt. (ref. J. Chem. Edu., 1980, 57, 7, 525)
3. Preparation of [Fe(H2O)6][Fe(N-salicyldeneglycinato)2]2.3H2O, its characterization using
IR, UV-Vis, magnetic susceptibility and analysis of Iron.(ref. Inorganica Chimica Acta,
1977, 23, 35).
4. Preparation of [Ni(NH3)6]Cl2 its characterization using IR, UV-Vis, magnetic susceptibility
and analysis of Nickel and NH3. (ref. Marr and Rockett, 1972).
5. Preparation of [Ni(ethylenediamine)3]Cl2 its characterization using IR, UV-Vis, magnetic
susceptibility and analysis of Nickel. (ref. Marr and Rockett, 1972, page 270).
6. Preparation of [Fe(NO)(S2CN(Et)2)2] its characterization using IR, UV-Vis, magnetic
susceptibility and analysis of Fe(II). (ref. Marr and Rockett, 1972, page 262, J. Chem. Soc.
1962, 84, 3404).
7. Preparation of octahedral and tetrahedral complexes of dichlorodipyridylcobalt(II),
differentiate them using IR, UV and magnetic properties. Estimate Co(II) from one of
them. (ref. Marr and Rockett, 1972, page 375, Inorganic Chemistry, 1966, 5, 615).
8. Preparation of VO(acac)2 and its piperidine complex, characterize using IR, UV and
magnetic moment. Estimate for V(IV). (ref. Marr and Rockett, 1972, 243).
9. Preparation of diaquotetraacetataocopper(II), magnetic susceptibility IR and UV-Vis,
analysis of Copper(II).
10. Preparation of cis- and trans- potassium dioxalato diaquochromate(III). Interpretation of
IR, UV and magnetic properties. Estimation of Chromium. (ref. Marr and Rockett, 1972,
page 386).
11. Preparation of HgCo(NCS)4 , its IR and measure its magnetic moment. (ref. Marr and
Rockett, 1972, page 365).
38
M.Sc. (Chemistry) (Semester-III) (FOR COLLEGES)
12. Preparation of sodium tetrathionate, interpretation of its IR and analysis using potassium
iodate. (ref. Marr and Rockett, 1972, page 214).
13. Preparation of Potassium dithionate, interpretation of its IR and analysis using potassium
iodate. (ref. Marr and Rockett, 1972, page 214).
14. Preparation of bis(acetylacetonato)copper(II), UV-Vis, and IR, magnetic studies,
Demonstration of Jahn Teller effect by solution spectral studies. (ref. Bull. Chem. Soc.
Japan, 1965, 29, 852).
15. Preparation of salicylamide complexes of Copper(II). IR, UV, magnetic data and analysis
of Cu(II). (ref. Indian J. of Chem., 1977, 15A, No. 5, 459; ibid, 1971, 9, 1396).
16. To prepare a macrocyclic ligand 5,7,7,12,14,14-hexamethyl-1,4,8,11-tetraazacyclo
tetradeca-4,11-dienedi(hydrogeniodide) and its complex with Ni(II). Study IR, NMR and
UV-Vis of ligand and complex and magnetic properties of complex. To analyze for Ni and
I. (J. Chem. Edu. 1977, 79, 581).
17. Preparation and resolution of tris (ethylenediamine) cobalt (III). UV-Vis, NMR, IR, optical
rotation of the resolved complexes. ((ref. Marr and Rockett, 1972, page 386).
Recommended Book:
60 hrs. M. Marks: 75
Section-B: 12 short answer type questions are to be set. Eight questions are to be attempted.
Maximum length of the answer can be upto 2 pages. In papers having 75 marks, each question
will be of 41/2 marks, total weightage being 36 marks.
Section-C: Four questions are to be set. Two questions are to be attempted. In this section there
will be descriptive questions, derivations, synthesis, structure and bonding, reactions and
conversions etc. Maximum length of answer can be upto 5 pages. In papers having 75 marks,
each question will be of 12 marks, total weightage being 24 marks.
Books Recommended:
Section-B: 12 short answer type questions are to be set. Eight questions are to be attempted.
Maximum length of the answer can be upto 2 pages. In papers having 75 marks, each question
will be of 41/2 marks, total weightage being 36 marks.
Section-C: Four questions are to be set. Two questions are to be attempted. In this section there
will be descriptive questions, derivations, synthesis, structure and bonding, reactions and
conversions etc. Maximum length of answer can be upto 5 pages. In papers having 75 marks,
each question will be of 12 marks, total weightage being 24 marks.
Types of solids, band and bond theories, crystal lattice energy, point defects in metals and ionic
compounds, energy and entropy of defects, their concentration, diffusion and electrical
conduction via defects, non stoichiometry types, colour centres and electrical properties of alkali
halides, electron theories for metal conduction in metals , in insulators, impurity semi
conductors, reactions in organic solids, photochemical reactions, solid-solid reactions,
decomposition and dehydration reaction.
Macromolecules (15)
Types of polymers, regular and irregular polymers, synthesis of polymers by chain and step
reactions, physical properties of solid polymers(crystallinity, plasticity and elasticity),
vulcanization of rubbers, molecular mass determination by osmometry, viscometry, light
scattering and ultracentrifuge methods, number and mass average molecular masses, polymer
solutions, factors affecting the solubility of polymers , conducting polymers,doping of polymers,
mechanism of conduction, polarones and bipolarons,
Factors affecting glass formation, oxide glasses, electronegativity and bond type, viscosity,
structural effects(zachariasen’s rule(1932), criteria of SUN and Rawson, thermodynamics of
glass formation, behavior of liquids on cooling, kinetics of crystallization and glass
formation,structure of glasses: vitreous silica, silicate glasses, vitreous B2O3 and borate glasses,
viscosiy, electrical conductivity of glasses and the mixed alkali effect, commercial silicate and
borate glasses, metallic glasses , glass ceramics, refractories, important glass-ceramics
compositions, properties of glass ceramics, applications.
44
M.Sc. (Chemistry) (Semester-IV) (FOR COLLEGES)
Methods of preparation- conventional ceramic methods, hot pressing and hot static pressing
techniques, precursor method, gel method, co-precipitation method, glass crystallization
methods, vacuum techniques- chemical vapor deposition method. , organic superconductors, ,
magnetism in organic materials, magnetic nano materials, energy storage materials, nano
materials for targeted drug delivery,, fullerenes as superconductors.High temperature ceramic
superconductors, electrical and magnetic properties of superconductors, critical temperature Tc,
thermodynamics of superconductors, London equation, BCS theory, applications.
Books Recommended:
Books:
1. An Introduction to Modern Experimental Organic Chemistry, R.M. Roberts, J.C.
Gilbert, L.B. Rodewald and A.S Wingrove, Holt Rinehart and Winston Inc, New
York. 1969.
2. Vogel’s Text Book of Practical Organic Chemistry.
3. Laboratory Experiments on Organic Chemistry, R. Edemas, J.R. Johnson and
C.F. Wilcox, The Macmillan Limited, London, 1970.
4. Modern Projects and Experiments in Organic Chemistry, J.R. Mohrig,
C.N. Hammonad, P.F. Schatz and T.C. Morrill, W.H. Freeman and Company,
New York 2003.
46
M.Sc. (Chemistry) (Semester-IV) (FOR COLLEGES)
Advanced Practicals
Inorganic Synthesis (Practical)
Course Hrs.: 90 Max. Marks: 50
Credit Hrs. 06 Pass Marks: 20
3. Synthesis and characterization of the Ni(II) complex of a Schiff-base ligand derived from
Salicylaldehyde and ethylenediamine.
a) Synthesis the Schiff-base lignad.
b) Interpret the 1H NMR and IR spectra of the ligand.
c) Synthesis the Ni(II) complex of the ligand and compare its IR spectrum with that of
the ligand.
Book:
1. G. Marr, B. W. Rockett, Practical Inorganic Chemistry (1972).
2. I. Grenthe, E. Nordin, Inorganic Chemistry, 18 (1979) 1869–74.
3. J.C. Bailar, M. Eldon, Inorg. Synth. 1 (1939) 35–38.
47
M.Sc. (Chemistry) (Semester-IV) (FOR COLLEGES)
Advanced Practicals
Physical Chemistry (Practical)
CHEMICAL EQUILIBRIUM
1. Study the effect of solvent on the conductance of AgNO3/Acetic acid and determine the
degree of dissociation and equilibrium constant in different solvents and their mixtures
(DMSO, DMF, dioxane, acetone, and water) and test the validity of DEBYE-
HUCKEL-ONSAGER’S equation.
2. To determine acid and base dissociation constant of amino acid pH metrically.
3. To calculate thermodynamic parameters, G, S and H for the reaction,
Zn + Hg2SO4 2Hg + Zn SO4 by emf measurement.
CHEMICAL KINETICS
4. Study the salt effects and the solvent effect on the rate law of alkaline hydrolysis of
crystal violet.
5. Determine the degree of hydrolysis and hydrolysis constant of
CH3COONa/NaCl/aniline hydrochloride.
6. Determine the order of reaction by analyzing the kinetic dependence of individual
reactant (e.g. saponification of ester).
7. Determine the energy of activation for the reaction studied above.
ACTIVITY AND ACTIVITY COEFFICIENTS
10. Draw the phase diagram for any one of the following three component partially
immiscible liquid systems.
i) DMSO/water/benzene ii) water/benzene/acetic acid
POLAROGRAPHIC TECHNIQUES
11. Estimation of ions in mixture of Pb2+ and Cd2+ by successive reduction. Evaluate
diffusion coefficient of Cd2+
12. Polarographic determination of Cu and Zn in the given sample of brass.
13. Determine stability constants of Cd2+ with EDTA.
SPECTROPHOTOMETRIC METHODS
14. To study the effect of extended conjugation on the wave lengthy of maximum
absorption of organic compounds.
48
M.Sc. (Chemistry) (Semester-IV) (FOR COLLEGES)
ADSORPTION
15. To determine the adsorption isotherms of heavy metals like Cd, Zn, Cr, Pb. Ni by
using nonconventiopnal adsorbents.
TURBIDITYMETRY
16. To determine concentration of sulphate ions with the help of turbidity meter.
17. Determine the CMC by turbidimetric method.
18. To draw calibration curve for the concentration determination of potassium ions by
flame photometry and to study the least square fitting of the data.