EE MOCK Test 2 Jan 2017 Questions Only
EE MOCK Test 2 Jan 2017 Questions Only
EE MOCK Test 2 Jan 2017 Questions Only
Pharmacy Prep
EE FINAL MOCK TEST 2
1. Colon transit time measurement is used in diagnosis of?
A. Prostate cancer B. constipation C. Heartburn D. Prokinetic effect E.
Fever in children
2.Which of the following is incorrect statement about body cavities and membranes?
A. dorsal body cavity divided into cranial cavity and vertebral cavity
B. cranial cavity host the brain
C. Ventral body cavity consist of thoracic, abdominal, and pelvic cavity
D. Pelvic cavity consist of digestive organs, peritoneal cavity
3. A women clients comes at your pharmacy for codeine syrup for her 3 yo daughter cough
symptoms. She is allergy to amoxicillin and otherwise healthy child. What is pharmacist
concern?
A. Penicillin allergy B. age C. body weight D. other symptoms
6. Escape of the fluids from blood capillaries or vessels to the surrounded tissues is termed
as?
A. Infiltration B. Extravasations C. Intramuscular D. Transdermal E. Vesicant
9. Calculate the mark up on cost. A regular customer of your pharmacy get refill of
rosuvastatin 10 mg for 3 mo and gliclazide 30 mg for 3 m. Each 3 mo is $120 and $150.
Prescription fee is $11. Patient has prescription coverage of 70% for drugs only. What patient
pays?
A) 211 B) $103 C) $189 D)$200
10. Which of the following is the dependent variable in statistical analysis determining risk
factors for hypertension?
A. Age B. Gender C. Demographic D. Hypertension E. body weight
Ans. D
11. What is a rate of constant of the drug having initial concentration of drug 1000 mg/ml and
100 mg/ml after 90 minutes?
a. 0.025 min-1 b.0.5 min-1 c. 2.2 min–1 d.3.2 min-1
14) Collect data after both disease and exposure. Measured by cross sectional study
A) Prevalence B) Incidence C) Validity D) Sensitivity E) Specificity
18) Insertion of genes into an individual cells and tissues to treat a disease such as hereditary
diseases is referred as?
A) DNA recombination
B) Cloning
C) Gene therapy
D) Retrovirus
E) Reverse transcriptase
19) Which of the following has been shown to have a relationship to carcinoma of the cervix?
a) Papilloma virus
b) Varicella-zoster virus
c) Herpes virus type I
d) Herpes virus type II
e) None of the above
23) A patient comes to pick up refills alprazolam 0.5 mg tablets, 15 days before refill time,
what action is appropriate?
A) Ask him to come just before 4 to 5 days before refill
B) Call doctor to get refill date change
C) Ask patient reason for early refill
D) Go to emergency or walk in clinic to get medication
E) Refuse refills and educate patient about compliance
26) Which of the following abbreviation is categorized dangerous abbreviation by the Institute
of safe Medication Practices (ISMP)
A) Q4H B) HS C) IU D) Daily E) Once week
28. A man wearing a mask and brandishing a weapon enters your pharmacy and demands
that you hand over the keys of the narcotics cupboard. What do you do?
A. Hand the keys to him immediately
B. Pretend to look for the keys in order to delay him
C. Try to reach for the phone to alert the police or security
D. Ask patient if you could be helpful by any means
E. Leave the pharmacy immediately
33) A patient receiving phenytoin 200 mg BID has a steady-state level of 8 mg/L. The
physician increases the dose to 300 mg BID. What steady-state concentration would you
expect?
a) Greater than 8 mg/L but, less than 12 mg/L
36. Cellular protein synthesis is expressed by DNA, RNA to ribosome. Which of the following is
the correct process?
A) Transcription occurs before translation
B) Translation occurs before transcription
C) Transcription occurs after translation
D) Transcription occurs in ribosomal RNA
E) Translation occurs on DNA template
37) A patient cannot afford to buy new medication that is not covered by his insurance plan.
Pharmacist called his doctor and asked him to change the medication into another medication
covered by the patient’s insurance plan. Which ethical principle did the pharmacist follow?
a) Beneficence b.Veracity c.Justice d. Nonmaleficence Fidelity
38. What drug act by inhibits the conversion of testosterone to the androgen 5-alpha-
dihydrotestosterone?
A. Tamoxifen B. Clomiphene C. Raloxefine D. Finasteride
E-Alendronate
42) Which one of the following is not a side effect associated with the use of B 2 agonists in
asthma?
a) Tremor resulting from B 2 receptor activation
b) Tachycardia resulting from B 1 receptor activation
c) Bradycardia resulting from B 1 receptor activation
d) Headache and apprehension resulting from vasodilatation
43) Which of the following reference books contain information about infant formula milk?
A) Compendium Pharmaceutical Specialties
B) Pediatric handbook
C) Compendium of Therapeutic Minor Ailment
D) Martindale
E) Compendium of Therapeutics choices
45) Protrusion of upper part of stomach into thorax through a tear is defined as?
A. Peptic ulcer b. Irritable bowel syndrome C. Crohn's disease D. Hiatal hernia
46. Advantages of nasal route over oral route absorption of drugs may include:
I- Nasal route has a higher surface area
II. Nasal route has more blood vessels
III- Nasal route has a higher onset of absorption
A-I only B-III only C-I and II only D-II and III only E-I, II and III
47. Which of the following risk increase after hip or knee replacement surgery?
A. Myocardial infarction B. stroke C. Angina D. Vein thrombosis
48) which of the following is an infectious complication associated with HIV if the CD4 is 350?
A. Mycobacterium avium, complex
B. Oral candidiasis
C. Pneumocystis carinii pneumonia
D. Hodgkin's lymphoma
E. All of the above
49. When you acquire business, what is the first step you should plan to do?
A. Talk to your competitors
B. Check prescription fee of other pharmacies in area
C. Meet prescribers in area
D. Geographical market area analysis
E. Check the salary of staff
50. There are 9 cranial nerve. Of these cranial nerve, the vagus nerve?
A. sensation from visceral (internal) organs and parasympathetic motor regulation of visceral
organs
B. serves muscle that move head, neck, and shoulders
C. serves muscles of the tongue
D. Equilibrium and hearing
51. A very frequent customer at your pharmacy, request for 15 days supply of Lipitor 10 mg
tablets. Next few hours he has to take a flight for vacation. Currently all walk-in-clinics are
closed and his physician is not available for prescription. Customer has no prescription and no
refills of Lipitor? According to extended scope of pharmacy practice pharmacist dispensed 15
days of drugs? This is defined as?
A. Adaptation
B. Advancing a drug
C. Pharmaceutical opinion
D. Professional discretion
E. Professional judgement
54. What types of drugs having these properties SHOULD NOT be formulated into SR forms
A) Poor solubility (dissolution rate is limiting step)
B) Very long half-life (no need) or very short half life (need very large amounts)
C) Very high potency (individual variation increase high dose)
D) Narrow margin of safety e.g. digoxin
E) All of the above
55. Which of the following resources would provide the most up-to-date answer when
checking new approved drug marketed in Canada?
a) eCPS
b) Health Canada's drug product data base
c) Food and Drug Administration website
d) Martindale’s
e) Compendium of Therapeutic choices
61. Generally, elixirs do not require antimicrobial preservatives. The reason is:
A. They contain high sugar content.
B. If they contain greater than 12% alcohol, they are self-preserving.
C. The active ingredient is usually an antimicrobial agent.
D. The active ingredient is usually an antimicrobial agent.
E. They are only used as vehicles. Final product must contain a preservative.
62) All the following are examples of long acting benzodiazepines, EXCEPT:
a) Clonazepan b) Diazepam c) Chlorazepate d) Flurazepan e) Temazepan
63) ABC pharmacy revenue for the last financial year was declined. The financial statement of
pharmacy reflect which of the following?
A. increase in revenue
B. Increase in net profit
C. decrease in net profit
D. increase in expenses
E. Decrease in expenses
64. Using the following correct procedures can reduce the presence of micro organisms in
parenteral products:
A) Using 0.22 micron filter
B) Working in a laminar flow hood
C) Using aseptic techniques
D) Preparation by qualified personal
E) All of the above
68. A new drug require $20,000 more than older drug per deep vein thrombosis? What is the
type of the study? What type of pharmacoeconomic methodology is used to analyse this?
A. Cost effective analysis
B. Cost benefit analysis
C. Cost minimization analysis
D. Cost utility analysis
69) A pharmacist is required to give knowledge of drugs and supply the patient with enough
pieces of information to overcome the patient ignorance. This is done by:
a) Written information only
b) Verbal information only
c) Verbal and written information
d) Magazines and folders information
e) Video information
72) GLP-1 analog are structurally and functionally same as human GLP-1. When administered
subcutaneously they increase GLP-1 action by five folds. Which of the following is a GLP-1
analog?
A. Canagliflozin B. Sitagliptine C.Exenatide D. Linagliptine E. Glimepiride
73. You are working as pharmacist in pharmacy A. The Pharmacist in pharmacy B was breaking
a pharmacy law?
A. Complain to college of pharmacy
B. Talk to manager of pharmacy B
C. Ignore it is not your pharmacy problem
D. Complain to police
74) Penicillin should be administrated 1 hour before meals or 2 to 3 hours after meals in order
to:
A. Improve the bioavailability
B. Maximize the dissolution rate
C. Avoid interaction with calcium ions
76) Insurance companies pay for the drugs of cheapest price of substituted medications.
According to the following data which medication could be chose?
a) 40 mg bid with a cost of $0.55/tablet
b) 20 mg qid with a cost of $0.60/tablet
c) 80 mg qd with a cost of $1.90/tablet
79. A results in statistically significant and reject the null hypothesis, when in fact null is true?
A. type 1 error B. type 2 error C. statistical significant D. confidence interval
80. According to Institute of safe medication practices (ISMP), which of the following drug
require label as high alert?
A. Simvastatin B. Lisinopril C. Digoxin D. progesterone E. Estrogen
81. A patient checks the blood pressure in pharmacy. The patient blood pressure was 140/90.
Pharmacist assist patients to double check the blood pressure. The patient blood pressure
was 140/90 What is appropriate action?
A. patient should be recommend to do lifestyle modifications to control blood pressure
B. patient should be referred to doctor to confirmation of blood pressure.
C. patient should be referred to emergence
D. patient blood pressure is not too high so patient need not to worry.
E. Pharmacist should check again patient blood pressure
82) Four types of physician, and their patient involved in study. Which non-parametric
method is appropriate
A. T-test B. Chi-square C. Anova D. F-Test E. Mean
85) A drug was wrongly dispensed to a patient what is the main concern?
A. Legal action B. Financial Liability C. Patient safety D. Drug effectiveness
E. Licence suspension
86) You are to prepare 750 mg medication in 75 mL for infusion over 30 minutes, using a 10-
drop set. How many drops/min will that be?
A. 20 drops/min B. 25 drop/min C. 30 drops/min D. 10 drops/min E. 5 drops/min
87) You are requested to add 44 mEq of sodium chloride (NaCl) to an IV bag. Sodium
chloride is available as a 4 mEq/ml solution. How many milliliters will you add to the bag?
a. 20 ML b. 8 mL C. 11 mL D. 15 mL E. 25 mL
88) Which of the following receptors are mediated by chemotherapy induced nausea and
vomiting?
A. type 1 serotonin B. type 2 serotonin C. type 3 serotonin D. type 4 serotonin
91) The molecular weight of magnesium sulfate (Mg 2+ SO 4 2-) is 120 mg and its valence is
2. How many milligrams does 1 mEq of magnesium sulfate weigh?
A. 20 mg B. 40 mg C.60 mg D. 80 mg E. 100 mg
92) An average adult has a body surface area of 1.72 m2 and requires an adult dosage of
12 mg of a given medication. The same medication is to be given to a child in a pediatric
dosage. If the child has a body surface area of 0.60 m2, and if the proper dosage for pediatric
and adult patients is a linear function of the body surface area (in other words, think of the
child as a small adult), what is the proper pediatric dosage?
A. 7mg B, 4 mg C. 6 mg D. 8 mg E. 10 mg
93. Which of the following is not available as over the counter drug?
A. bisacodyl b. mupirocin c. Cetirizine D. diclofena topical E. ibuprofen 300 mg
94) You have a stock solution that contains 10 mg of active ingredient per 5 ml of solution.
The physician orders a dose of 4 mg. how many milliliters of the stock solution will have to be
administered?
A. 2 mL B. 4 mL C. 6 mL D. 8 mL E. 10 mL
95. A researcher develops a new drug to prevent the common cold in children over the of
two. 1000 children received placebo and 1000 received the drug. During the one-year follow
up the research diagnosed colds in 2.5% of the kids on placebo and in 2% of the active
treatment. What is the absolute risk reduction?
A) 0.5% B-20% C-10% D-40% E) 5%
96. Who set the prices of prescription brand name of patented medicine drugs in Canada?
A)Patented Medicine Price Review Board (PMPRB) B)Health Canada C)Provincial government
D)Federal government E)Manufacturer
97. Which of the following drug combination therapy most likely associated with serotonin
syndrome?
A) Fluoxetine and bupropion
B) Tranylcypromine and paroxetine
C) Amitriptyline and selegiline
D) Rasagiline and fluoxetine
E) Bupropion and venlafaxine
98) All of the following statements with regard to the autocoids prostaglandin are correct
EXCEPT,
a) It is a fatty acid
b) It is derived from essential amino acids
c) It is thought to be involved in the inflammatory process
d) It is thought to be involved in the reproductive process
e) Its synthesis may be inhibited by non steroidal anti-inflammatory agents
99. Diabetic supplies e.g. blood glucose testing agents, syringes, lancets are identified as?
A) Drug identification number
B) Natural product number
C) Product identification number (PIN)
D) Homeopathic Medicine Number (DIN-HM)
E) Universal product code
100) Which phase involves the comparison between the test drug and the standard drug in
the process of developing a new drug?
A. Preclinical trial B-Phase I trial C- Phase II trial D- Phase III trial E- Phase IV trial
102) MK is 60 year old post menopausal women, recently had hysterectomy and currently
suffering from vasomotor symptoms. Which of the following is hormonal therapy is
appropriate?
A. Androgen B. Estrogen C. Progesterone D. estrogen and progesterone
E. no hormonal therapy is recommended
103) What is suitable reference source to locate detail information about drug-grape fruit
juice interaction?
A. Comoendim of therapeutic choices B. USP-DI Vol. I C-PDR D-CPS E-Merck Manual
104. Which of the following is the incorrect about a general anesthetic ketamine regulations?
A. It is regulated as straight narcotic
B. Ketamine should be given only by written prescription.
C. Ketamine can be refilled only 3 times maximum
D. Ketamine prescription cannot be transferred
E. Ketamine prescription hard copy should be stored for minimum 2 years
106) What is correct about Reverse Phase High Performance Liquid Chromatography?
I- Mobile phase is a non-polar solvent
II- The particle size of stationary phase affects resolution
III) Utilize high pressure pump to increase efficiency in the resolution
a) I only b) III only c) I and II only d) II and III only e) I,II,III
108. MK is 55 yo man just diagnosed with COPD. He smokes half pack of cigarettes daily. His
pharmacist advised and counselled to quit smoking. MK started nicotine patch. He returns
after 3 days complains he is not able to sleep or feeling insomnia?
A. Insomnia is nicotine withdrawal symptom
B. Insomnia is side effect of nicotine patch
C. Insomnia is due to COPD
D. All nicotine product can cause insomnia, he should be switched to bupropion
109) A customer of your pharmacy using metformin 500 mg bid and glyburide qd. Complains
to have gritty and sandy feeling in eye. What is appropriate to do?
A)Refer to doctor because of diabetic condition
B)Refer to doctor because sandy and gritty feeling in eye is conjunctivitis.
C)Refer to doctor because glyburide side effect is dry eye
D)Refer to doctor because metformin side effect is dry eye
E)Refer to doctor because these are side effects of anticholinergic drugs
111) Acetylcholine and epinephrine antagonize the effect of each other. What type of
antagonism is it?
A. Physiological antagonism B. Somatic antagonism C-Competitive antagonism
D-Neutralizing antagonism E-Opposite antagonism
114) A patient reports to emergence with diabetic keto acidosis medical condition. What
incorrect about diabetic ketoacidosis?
A) the major ketone is beta hydroxybutyric acid
B) it is mainly occurs in type 1 DM
C) Fruity smell is symptoms of diabetic ketoacidosis
D) diabetic ketoacidosis is NOT life threatening
115) A 9 years old boy is suffering from absence seizure. Which drug is recommended for this
patient?
a) Phenytoin b) Ethosuximide c) Gabapentin d) Carbamazepine e) Pregabalin
116) Which of the following contraceptive methods prevents gonorrhea and Chlamydia
infections?
A) Transdermal contraceptives
B) Intrauterine device
C) Vaginal cream
D) Sub dermal progesterone implants
E) None of the above
120) Which of the following special population has high water content in body?
121) A nurse mistakenly administered double dose of insulin to a 80 year old senior diabetic
patient? Which of the following symptoms may NOT occur
A. Confusion B. Tremor C-Palpitation D. Hunger E. Diarrhea
122) Which of the following is NOT screening test for cancer?
A) Prostate specific antigen B) Digital rectal exam C) Pap smear D) ESR E) Colonoscopy
123) All of the following drugs are associated with decreased appetite, Except?
A. Metformin B. Clomipramine C. Bupropion D. Atomoxetine E. Methylphenidate
124) A prescription signs as indicates “ii gtt. au qd x 1/52”. It can be interpreted as:
a. 2 drops in each of both the ears four times a day for 1 week
127. Which of the followings is Not a correct recommendation for a patient with Congestive
Heart Failure?
A-Restricted sodium intake (<2 to 3 g/day) in all patients
B-Regular physical exercise like walking, jogging, swimming in all patients
C-Control obesity, hypertension and diabetes mellitus if present
D. Restricted fluid intake (1.5 to 2L/day) in all patients
E-Allowed moderate alcohol consumption in patients with less severe condition
131. Which of the following statement is incorrect about alcohol and drug interactions?
A. Alcohol and metronidazole can give disulfiram reactions
B-Alcohol and metformin can give lactic acidosis
133) All of the following are true about transdermal patches? except
A) drug with short half life and large quantity can be used
B) Effectiveness for a long period of time allowing for retention of patch for a number of hours
C) Consistent blood drug level of drug is achieved.
D. Fentanyl patch is applied for 48 hours
E. Fentanyl has short half life
136. A patient using glargine insulin and insulin lispro morning and bedtime. Patient feels
hypoglycemia at bedtime? What is appropriate to do?
A. decrease dose of glargine
B. decrease dose of lispro
C. Recommend to take snacks before bedtime
D. Recommend to avoid lispro insulin
137) Contraceptive methods that may protect STDs such as, gonorrhea, syphilis, chlamydia,
and AIDS?
A) Vaginal rings B) Spermicidal gel C-Intrauterine devices D-Vaginal cream E-Condoms
138. A pharmacy cost of drug for a over the counter drug is $2.00 and sales price is $2.50.
Calculate the mark up (percentage of margin)?
A) 25% B) 30% C) 40% D) 50% E) 80%
139) A prescription sign as indicates “1 gtt ou qid x 10”. It can be interpreted as:
141) Antibiotics with high partition coefficient from bacterial cell wall have?
A) lower absorption
B) higher absorption
C) absorption of drugs does not depends on partition coefficient
D) absorption of drugs does not depends on bacterial cell wall
E) partition coefficient <1 has high absorption
143. Who promotes, sets and implements model standards of pharmacy practice in
Canada?
A-Provincial colleges of pharmacy
B-Pharmacy examination of board of Canada
C-National association of pharmacy regulatory authority (NAPRA)
D. Federal government
144. The axillary nerve supplies which one of the following muscles?
A. Deltoid. B. Supraspinatus. C. Teres major. D. Infraspinatus. E Latissimus dorsi.
145) Which of the following an example of luteinizing hormone releasing hormone (LHRH), a
hormone that is naturally produced in the body and involved in the release of testosterone.
Administering such agents reduces testosterone production. All of the following are example
of analog of LHRH that is used as chemotherapy for prostate cancer treatment? except
A) goseriline acetate B) buserelin acetate C) leuprolide acetate D) Finasteride
149. MP is 49 year old male, has been prescribed amlodipine 10 mg daily to treat
hypertension. What is incorrect about amlodipine?
A) Bradycardia
B) may cause peripheral or ankle edema
C) dihydropyridine is essential for activity
D) Avoid taking grapefruit juice
E) may cause orthostatic hypotension and headache
151. Which of the following group is NOT covered by the federal drug benefit program?
A)inmates B)refugees C)seniors >65 yr old D)natives or aboriginals E)RCMP
152. The hospital pharmacist is asked for advice from a physician after a newly admitted
patient is diagnosed with ischemic stroke. In the selection of drug therapy for the initial
management of this patient, the pharmacist would find all of the following resources useful,
EXCEPT:
A) Published clinical guidelines
B) Harrison’s principles of internal medicine
C) Cochrane database
D) Compendium of Therapeutic Choices
E) Compendium of Therapeutic Minor Ailment
153. The practice of writing part of a drugs name in upper letter to help distinguish?
154. A compounding technique used in preparing creams, ointment, and supps that involves
integrating a soluble solid substance (active ingredient) into an oleaginous base by first
melting the base under low heat, then mixing the solid substance into the melted base and
allowing the mixture to cool and solidify is termed as?
A. Geometric dilution B. Fusion C. Trituration D. Levigation E. Pulverisation
155.MP is 50 year old women. She is using metformin 1000 mg bid for the past one year but
her blood glucose levels HbA1C is >8%. What is appropriate to add medication to control her
blood glucose levels?
A. Sitagliptine B. Acarbose C. Liraglutide D. Gliclazide E. Insulin
156. JP 60 yo man hospitalized for a surgical procedure. A clinician describes the surgical
procedure. This is termed as?
A. Confidentiality B. Consent C. Disclosure D. Ethical standard E. Legal requirement
157. A chemical drug-drug incompatibility between gentamycin and penicillin's takes place
thus inactivates both antibiotics. Gentamycin N-acetylation by the penicillin's?
A. Beta lactam ring B. Amide bond C. Ester on dihydrothiazine ringD. Thiazolidine ring
E. carboxylic acid on penicillin
160. The "contact angle" is an important parameter reflective of the angle that a droplet of
the liquid makes with the solid surface at the point of contact. This parameter is wetting
phenomenon is used to measure ?
A. Degree of wetting of a solid by a liquid
B. Rate of dissolution
C. Rate of disintegration
D. Rate of solubility
162. Health Canada's advisories and product recalls are related to?
A) Information about drug warnings or advisories.
B) Information about drugs that are recalled
C) Information about products that are discontinued
D) When a product recalled. This should be tracked by product lot number.
E) All of the above
163.Edema is?
A) excessive accumulation of water in the extra cellular fluid
B) excessive accumulation of fluids in the intra cellular fluid
C) Accumulation of fluids in the extra cellular's spaces
D) Excessive accumulation of water in the tissues
E) Excessive accumulation of fluids in peritoneal cavity
166.A clinical trial for a drug A on 300 patients shows no difference. Again trail done on
30,000 patient’s shows difference. What is appropriate biostatical hypothesis error?
A) Type I error
B) Increase in sample size
C) Type II error
D) Probability of error
E) None of the above
B. Weakening of bone
C. Bone fracture due to osteoporosis
D. Osteopenic conditions of bone
E. Paget disease
177. Which of the following can be used for evidence based reference for decision making?
A) Compendium of Therapeutic choices
B) Compendium of Therapeutic Minor ailments
C) Compendium of pharmaceutical specialties
D) Cochrane review database
E) Martindale
178. The pharmacy staff are complaining about one pharmacist who has just come back from
maternity leave, also patient complains because of the frequent errors in Rx filling and due to
delay in their Rx filling due to lengthy phone calls. What is the best response from the
manager especially when he asked the pharmacist and knew that a problem with the nanny of
the baby is found and she is looking for a better one:
A. He might tell the pharmacy staff and patient that this is a temporary situation and it will be
solve soon.
B. He might tell the pharmacist that the existing behavior is unacceptable and so a discipline
might be applied if it is continued
C-Hire more staff temporarily to help the pharmacist, ↓↓ frequency of errors
D-Arrange a trusted co-worker to follow the pharmacist’s behaviour to ensure that the future
decision is the right one.
E-Apply a discipline for her
179.Who among the following patients can use oral contraceptives with caution?
A) Patient with deep vein thrombosis (DVT)
B) Patient with migraine and aura
C) Patient with BP >160/100 and uncontrolled hypertension
180. To prepare a solution of 25 mmols/L of NaCl, how many grams of NaCl should you use for
1L solution (MW of NaCl 58.5)
A.0.50 b.0.73 c.1,25 d.1.46 d.2.50
181. What is the minimum quantity that can be weight on a balance with sensitivity
requirements of 15 mg, where permissible error is 5%?
a) 100mgb) 200mg c) 300mg d) 400mg e) 500mg
183. What would be the loading dose of a drug to achieve a 20 mcg/ml steady state plasma
concentration? The apparent volume of distribution is 4.5 L.
A) 25 mg B) 35 mg C) 90 mg D) 56 mg E) 70 mg
185. Alpha 1-antitrypsin (A1AT) is produced in the liver, and one of its functions is to protect
the lungs from neutrophil elastase, an enzyme that can disrupt connective tissue. The
deficiency of alpha-1-antitrypsin can cause?
A. Diabetes
B. Cardiovascular diseases
C. Chronic obstructive pulmonary disease
D. Increase in low density proteins
E. Hypertension
186. The antipsychotic effects of the phenothiazines are probably the result of
a) release of serotonin in the brain
187. A 70 year old patient has chronic renal disease, which of the following is the pharmacist
least concern?
A. Enoxaparin B. Heparin C. Warfarin D. Ramipril E. Hydrochlorothiazide
188. Which one is the most appropriate antidepressant for a patient, who is already suffering
from sexual dysfunction?
A) Paroxetine B) Bupropion C) FluoxetineD. VenlafaxineE. Amitriptyline
191. Venous pooling occurs due to lack of sympathetic activity and loss of active muscle
function in the lower extremities and trunk musculature, this results more retention of blood
in veins. There are drugs know to induce venous pooling. What drugs more likely can cause
venous pooling?
A. Isosorbide dinitrate B. Propranolol C. Amlodipine D-Captopril
E-Hydrochlorothiazide
194. ACE, is a central component of the renin-angiotensin system (RAS), which controls blood
pressure by?
A. regulating the volume of fluids in the body and potent vasoconstrictor effect
C. blocking beta2 receptors
D. peripheral vasodilatation
E. decrease work load on heart
195. what day of menstrual cycle, the luteinizing hormone (LH) is surged?
A. day 1 of menstruation
B. day 5 of menstruation
C. day 14 of menstruation
D. day 21 of menstruation
E. day 28 of menstruation
196. The neurocranium consists of eight bones. Which of the following is not cranial bone
A. occipital bone B. temporal bone C. Parietal bone D. Facial bone E. Sphenoid bone
197. What is true about combination drug Acetaminophen 300 mg + codeine 8 mg + caffeine
15 mg
A. It is schedule 2 and can be given by pharmacist
B. Require prescription because it contain codeine
C. it is over the counter drug
D. It is straight narcotic and given by written prescription only
E-None of the above
199. Which of the following drug require to dispensed only by written prescription?
A) Lorazepam B) Clonazepam C) Methylphenidate D) OxyNeo E) Anabolic steroids