(D) All These

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Vitamins are 6.

Retinol and retinal are interconverted


(A) Accessory food factors requiring dehydrogenase or reductase in
(B) Generally synthesized in the body the presence of
(C) Produced in endocrine glands (A) NAD or NADP (B) NADH +
(D) Proteins in nature (C) NADPH (D) FAD
2. Vitamin A or retinal is a 7. Fat soluble vitamins are
(A) Steroid (A) Soluble in alcohol
(B) Polyisoprenoid compound containing (B) one or more Propene units
cyclohexenyl ring (C) Stored in liver
(C) Benzoquinone derivative (D) All these
(D) 6-Hydroxychromane
8. The international unit of vitamin A is
3. ß-Carotene, precursor of vitamin A, is equivalent to the activity caused by
oxidatively cleaved by
(A) ßCarotene dioxygenase (A) 0.3 pg of Vitamin A alcohol
(B) Oxygenase (B) 0.344 pg of Vitamin A alcohol
(C) Hydroxylase (C) 0.6 pg of Vitamin A alcohol
(D) Transferase (D) I .0 pg of Vitamin A alcohol
4. Retinal is reduced to retinol in intestinal 9. Lumirhodopsin is stable only at tempera-
mucosa by a specific retinaldehyde ture below
reductase utilising (A) -IOOC (B) -200C
(A) NADPH + H+ (B) FAD (C) -400C (D) -500C
(C) NAD 10. Retinol is transported in blood bound to
5. Preformed Vitamin A is supplied by (A) Aporetinol binding protein
(A) Milk, fat and liver U2Globulin
(B) All yellow vegetables ß-G10bulin
(C) All yellow fruits Albumin
(D) Leafy green vegetables

The normal serum concentration of 20. Vitamin D absorption is increased in


vitamin A in mg/100 ml is (A) Acid pH Of intestine

(A) 5-10 (B) 15-60 (B) Alkaline pH of intestine


(C) 100-150 (D) 0-5 (C) Impaired fat absorption
12. One manifestation of vitamin A deficiency (D) Contents Of diet
is 21. The most potent Vitamin D metabolite is
(A) Painful joints (A) 25-Hydroxycholecalciferol
(B) Night blindness (B) 1.25Dihydroxycholecalciferol
(C) Loss Of hair (C) 24, 25Dihydroxycholecalciferol
(D) Thickening Of long bones (D) 7-Dehydroch01esterol

13. Deficiency of Vitamin A causes 22. The normal serum concentration Of


(A) Xeropthalmia 25-hydroxycholecalciferol in ng/ml is
(B) Hypoprothrombinem ia (B) 60-100
(C) Megaloblastic anemia (C) 100-150 (D) 8-55
(D) Pernicious anemia 23. The normal serum concentration of 1 ,
25-
14. An important function of vitamin A is dihydroxycholecalciferol in pg/ml is
(A) To act as coenzyme for a few enzymes (A) 26-65 (B) 1-5
(B) To play an integral role in protein synthesis (C) 5-20 (D) 80-100
(C) TO prevent hemorrhages 24. The normal serum concentration of 24,25-
(D) To maintain the integrity of epithelial tissue dihydroxycholecalciferol in ng/ml is
15. Retinal is a component of (A) 8-20 (B) 25-50
(A) Iodopsin (B) Rhodopsin (D) 60-100
(C) Cardiolipin (D) Glycoproteins 25. A poor source Of Vitamin D is
16. Retinoic acid participates in the synthesis (A) Egg (B) Butter
Of (C) Milk (D) Liver
(A) Iodopsin (B) Rhodopsin 26. Richest source of Vitamin D is
(C) Glycoprotein (D) Cardiolipin
(A) Fish liver oils (B) Margarine
17. On exposure to light rhodopsin forms (C) Egg yolk (D) Butter
(A) All trans-retinal (B) Cis-retinal 27. Deficiency Of vitamin D causes
(C) Retinol (D) Retinoic acid (A) Ricket and osteomalacia
18. Carr-Price reaction is used to detect (B) Tuberculosis of bone
(A) Vitamin A (B) Vitamin D (C) Hypthyroidism
(C) Ascorbic acid (D) Vitamin E (D) Skin cancer
28. One international unit (IN) Of vitamin
19. The structure shown below is of D
(A) Cholecalciferol is defined as the biological activity of
(B) 25Hydroxycholecalciferol (A) 0.025 pg of cholecalciferol
Ergocalciferol (B) 0.025 pg of 7-dehydrocholecalciferol
(C) 0.025 pg of ergosterol
(D) 7-Dehydrocholesterol
(D) 0.025 pg of ergocalciferol
29. The ß-ring of 7-dehydrocholesterol is 38. All the following conditions produce a
real
cleaved to form cholecalciferol by or functional deficiency of vitamin K
(A) Infrared light
(B) Dim light (A) Prolonged oral, broad spectrum antibiotic
(C) Ultraviolet irridation with sunlight therapy
(B) Total lack of red meat in the diet
(D) Light Of the tube lights
(C) The total lack Of green leafy vegetables in
30. Calcitriol synthesis involves the diet
(A) Both liver and kidney (D) Being a new born infant
(B) Intestine 39. Vitamin K is found in
(C) Adipose tissue (A) Green leafy plants (B) Meat
(D) Muscle (C) Fish (D) Milk
31. Insignificant amount of Vitamin E is
40. Function of Vitamin A: (A)
present in Healing epithelial tissues
(A) Wheat germ Oil (B) Sunflower seed Oil (B) Protein synthesis regulation
(C) Safflower seed Oil (D) Fish liver Oil (C) Cell growth
32. The activity of tocopherols is destroyed (D) All Of these

41. Vitamin K2 was originally isolated


from
(A) Commercial cooking (A) Soyabean (B) Wheat gram
(B) Reduction (C) Alfa Alfa (D) Putrid fish meal
(C) Conjugation 42. Vitamin synthesized by bacterial in the
(D) All Of these intestine is
33. The requirement of vitamin E is increased
with greater intake of
(A) Carbohydrates
(B) Proteins 43. Vitamin K is involved in posttranslational
modification of the blood clotting
(C) Polyunsaturated fat factors by acting as cofactor for the
enzyme:
(D) Saturated fat (A) Carboxylase (B) Decarboxylase
34. Vitamin E reduces the requirement Of (C) Hydroxylase (D) Oxidase
(A) Iron (B) Zinc 44. Vitamin K is a cofactor for
(C) Selenium (D) Magnesium (A) Gamma carboxylation of glutamic acid
35. The most important natural antioxidant residue
is (B) ß-Oxidation of fatty acid
(A) Vitamin D (B) Vitamin E (C) Formation of y-amino butyrate
(C) Vitamin B 12 (D) Vitamin K (D) Synthesis of tryptophan
36. Tocopherols prevent the oxidation of 45. Hypervitaminosis K in neonates may
(A) Vitamin A (B) Vitamin D cause
(A) Porphyria (B) Jaundice
(C) Vitamin K (D) Vitamin C (C) Pellagra (D) Prolonged bleeding
37. Creatinuria is caused due to the deficiency
46. Dicoumarol is antagonist to
of vitamin
(A) Riboflavin (B) Retinol
(C) Menadione (D) Tocopherol

47. In the individuals who are given liberal 56. Both Wernicke's disease and beriberi
can
quantities of vitamin C, the serum ascorbic be reversed by administrating
acid level is (A) Retinol (B) Thiamin
(C) Pyridoxine (D) Vitamin B 12
(B) 2-4 pg/100 ml
57. The Vitamin Bl deficiency causes
(C) I-IOgg/lOO ml
(D) 10-20 gg/lOO ml (A) Ricket (B) Nyctalopia
(C) Beriberi (D) Pellagra
48. The vitamin which would most likely
become deficient in an individual who 58. Concentration of pyruvic acid and lactic
develop a completely carnivorous life acid in blood is increased due to deficiency
style is Of the vitamin
(A) Thiamin (B) Niacin (A) Thiamin (B) Riboflavin
(C) Vitamin C (D) Cobalamin (C) Niacin (D) Pantothenic acid
49. In human body highest concentration Of 59. Vitamin B, coenzyme (TPP) is involved in
ascorbic acid is found in (A) Oxidative decarboxylation
(A) Liver (B) Adrenal cortex (B) Hydroxylation
(C) Adrenal medulla (D) Spleen (C) Transamination
(D) Carboxylation
50. The vitamin required for the formation of
hydroxyproline (in collagen) is 60. Increased glucose consumption
increases
(A) Vitamin C (B) Vitamin A the dietary requirement for
(C) Vitamin D (D) Vitamin E (A) Pyridoxine (B) Niacin
(C) Biotin (D) Thiamin
51. Vitamin required for the conversion of p-
hydroxyphenylpyruvate to homo- 61. Thiamin is oxidized to thiochrome
in
gentisate is alkaline solution by
(A) Folacin (B) Cobalamin (A) Potassium permanganate
(C) Ascorbic acid (D) Niacin (B) Potassium ferricyanide
52. Vitamin required in conversion of folic acid (C) Potassium chlorate
to folinic acid is (D) Potassium dichromate
(A) Biotin (B) Cobalamin 62. Riboflavin is a coenzyme in the reaction
(C) Ascorbic acid (D) Niacin catalysed by the enzyme
53. Ascorbic acid can reduce (A) Acyl COA synthetase
(B) Acyl COA dehydrogenase
(A) 2, 6-Dibromobenzene (C) ß-Hydroxy acyl COA
(B) 2, 6-Diiodoxypyridine (D) Enoyl COA dehydrogenase
(C) 2, 6-Dichlorophenol indophenol 63. The daily requirement of riboflavin
for
(D) 2, 4-Dinitrobenzene adult in mg is
54. Sterilised milk lacks in (B) 1.2-1.7
(A) Vitamin A (B) Vitamin D (C) 2.0-3.5 (D) 4.0-8.0
(C) Vitamin C (D) Thiamin 64. In new born infants phototherapy may
55. Scurvy is caused due to the deficiency Of cause hyperbilirubinemia with
deficiency Of
(A) Vitamin A (B) Vitamin D (A) Thiamin (B) Riboflavin
(C) Vitamin K (D) Vitamin C (C) Ascorbic acid (D) Pantothenic acid