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    Pathophysiology Diagram of Asthma PDF

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    Yhenlee Rhizelle Marquez
    This document outlines the pathophysiology of asthma. It discusses pre-disposing factors like atopy and gender. It also examines intrinsic and extrinsic allergens that can trigger asthma symptoms. The allergens stimulate immunoglobulin E and mast cell degranulation, releasing inflammatory mediators like histamine. This leads to bronchiole constriction, edema in the airway walls, increased mucus production and other respiratory symptoms. Long term, asthma causes airway remodeling and hyperresponsiveness.

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    Pathophysiology Diagram of Asthma PDF

    Uploaded by

    Yhenlee Rhizelle Marquez
    319 views2 pages
    This document outlines the pathophysiology of asthma. It discusses pre-disposing factors like atopy and gender. It also examines intrinsic and extrinsic allergens that can trigger asthma symptoms. The allergens stimulate immunoglobulin E and mast cell degranulation, releasing inflammatory mediators like histamine. This leads to bronchiole constriction, edema in the airway walls, increased mucus production and other respiratory symptoms. Long term, asthma causes airway remodeling and hyperresponsiveness.

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    Pathophysiology Diagram of Asthma (1).pdf

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    This document outlines the pathophysiology of asthma. It discusses pre-disposing factors like atopy and gender. It also examines intrinsic and extrinsic allergens that can trigger asthma symptoms. The allergens stimulate immunoglobulin E and mast cell degranulation, releasing inflammatory mediators like histamine. This leads to bronchiole constriction, edema in the airway walls, increased mucus production and other respiratory symptoms. Long term, asthma causes airway remodeling and hyperresponsiveness.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    319 views2 pages

    Pathophysiology Diagram of Asthma PDF

    Uploaded by

    Yhenlee Rhizelle Marquez
    This document outlines the pathophysiology of asthma. It discusses pre-disposing factors like atopy and gender. It also examines intrinsic and extrinsic allergens that can trigger asthma symptoms. The allergens stimulate immunoglobulin E and mast cell degranulation, releasing inflammatory mediators like histamine. This leads to bronchiole constriction, edema in the airway walls, increased mucus production and other respiratory symptoms. Long term, asthma causes airway remodeling and hyperresponsiveness.

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    Pre-disposing factors:

     Atopy
     Female Gender
    Extrinsic Allergens: Intrinsic allergens:
    Food additives Exposure to allergies and causative factors Physiological and
    containing sulfites, dust, psychological stress, fatigue,
    molds, pollen, grass, Allergy injections, weather changes, anxiety
    tress and roaches Cortiscosteroids and genetic factors

    Immunoglobulin E stimulation

    Mast cell degranulate and release mediators


    Mast cell stabilizer

    Histamine
    Leukotrienes
    Bradykinin
    Eosinophilic chemotatic factor

    Localized Secretion of Cough and rhonchi


    edema in the Antihistamine mucus into the
    Dyspnea, walls of the bronchial
    prolonged small lumens
    respiration, bronchioles
    increased and spasm of
    respiratory the bronchiolar Mucus fills the
    rate smooth muscle lungs bases

    Inhibits alveolar
    Hyperresponsiveness Increased airway ventilation
    of airway resistance and airflow
    limitation Hypoxia
    Wheezing and During inhalation, Hyperventilation
    respiratory distress narrow lumen expand
    slightly allowing air
    to reach the alveoli
    Respiratory
    Alkalosis
    During exhalation,
    increased intrathoracic
    pressure closes the
    bronchial lumen
    completely. Air enter but
    cannot escape.

    Barrel chest and


    hyperresonance to
    percussion

    Legends:
    Risk and Predisposing Factors

    Manifestations

    Medications

    Reference
    Malones, R. (2018, May 24). Asthma Pathophysiology and Schematic Diagram. Retrieved
    from https://rnspeak.com/asthma-pathophysiology-and-schematic-diagram/
    Felson, S. (2020, June 12). Slideshow: A Visual Guide to Asthma. Retrieved from
    https://www.webmd.com/asthma/ss/slideshow-asthma-overview

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