SAFETY DATA SHEET Version 6.

5
Revision Date 21.01.2021
according to Regulation (EC) No. 1907/2006 Print Date 30.03.2021
GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifiers
Product name : Propylparaben
Product Number : PHR1010
Brand : Sigma-Aldrich
REACH No. : A registration number is not available for this substance as the
substance or its uses are exempted from registration, the
annual tonnage does not require a registration or the
registration is envisaged for a later registration deadline.
CAS-No. : 94-13-3
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Pte Ltd
(Co. Registration No. 199403788W)
1 Science Park Road
#02-14 The Capricorn, S'pore Sci. PkII
SINGAPORE 117528
SINGAPORE
Telephone : +65 6779-1200
Fax : +65 6779-1822
1.4 Emergency telephone
Emergency Phone # : 1-800-262-8200

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture
Not a hazardous substance or mixture according to Regulation (EC) No 1272/2008.
2.2 Label elements
Not a hazardous substance or mixture according to Regulation (EC) No 1272/2008.
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.

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SECTION 3: Composition/information on ingredients
3.1 Substances
Synonyms : Propyl 4-hydroxybenzoate
4-Hydroxybenzoic acid propyl ester

Formula : C10H12O3
Molecular weight : 180,2 g/mol
CAS-No. : 94-13-3
EC-No. : 202-307-7
No components need to be disclosed according to the applicable regulations.

SECTION 4: First aid measures

4.1 Description of first-aid measures
If inhaled
After inhalation: fresh air.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with
water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Remove contact lenses.
If swallowed
After swallowing: make victim drink water (two glasses at most). Consult doctor if feeling
unwell.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section
2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media
Suitable extinguishing media
Water Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
5.3 Advice for firefighters
In the event of fire, wear self-contained breathing apparatus.

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5.4 Further information
Prevent fire extinguishing water from contaminating surface water or the ground water
system.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Avoid inhalation of dusts. Evacuate the danger
area, observe emergency procedures, consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions
(see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid
generation of dusts.
6.4 Reference to other sections
For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditions
Tightly closed. Dry.
Store at room temperature.
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

8.1 Control parameters
Ingredients with workplace control parameters
8.2 Exposure controls

Personal protective equipment

Eye/face protection
Use equipment for eye protection tested and approved under appropriate
government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
This recommendation applies only to the product stated in the safety data sheet,
supplied by us and for the designated use. When dissolving in or mixing with other
substances and under conditions deviating from those stated in EN374 please
contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
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 Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested:KCL 741 Dermatril® L
This recommendation applies only to the product stated in the safety data sheet,
supplied by us and for the designated use. When dissolving in or mixing with other
substances and under conditions deviating from those stated in EN374 please
contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested:KCL 741 Dermatril® L

Respiratory protection
required when dusts are generated.
Our recommendations on filtering respiratory protection are based on the following
standards: DIN EN 143, DIN 14387 and other accompanying standards relating to
the used respiratory protection system.
Recommended Filter type: Filter type P1
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory
protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Control of environmental exposure
Do not let product enter drains.

SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties
a) Appearance Form: solid
Color: white
b) Odor odorless
c) Odor Threshold No data available
d) pH ca.6 - 7 at 20 °C
(saturated solution)
e) Melting Melting point: 96 - 98 °C
point/freezing point
f) Initial boiling point 301 °C at 1.011 hPa - OECD Test Guideline 103
and boiling range
g) Flash point 180 °C
h) Evaporation rate No data available
i) Flammability (solid, does not ignite - Flammability (solids)
gas)
j) Upper/lower No data available
flammability or

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 explosive limits
k) Vapor pressure 0,67 hPa at 122 °C
l) Vapor density No data available
m) Relative density 1,063 g/cm³ at 102 °C
n) Water solubility ca.0,4 g/l at 25 °C
o) Partition coefficient: log Pow: 2,88 - Bioaccumulation is not expected.
n-octanol/water
p) Autoignition No data available
temperature
q) Decomposition No data available
temperature
r) Viscosity Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
No data available

SECTION 10: Stability and reactivity

10.1 Reactivity
Forms explosive mixtures with air on intense heating.
A range from approx. 15 Kelvin below the flash point is to be rated as critical.
The following applies in general to flammable organic substances and mixtures: in
correspondingly fine distribution, when whirled up a dust explosion potential may generally
be assumed.
10.2 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.3 Possibility of hazardous reactions
Violent reactions possible with:
Strong oxidizing agents

10.4 Conditions to avoid

Strong heating.
10.5 Incompatible materials
Strong oxidizing agents
10.6 Hazardous decomposition products
In the event of fire: see section 5

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SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - male and female - > 5.000 mg/kg
(OECD Test Guideline 401)
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation - 4 h
(OECD Test Guideline 404)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: No eye irritation
(OECD Test Guideline 405)
Respiratory or skin sensitization
Local lymph node assay (LLNA) - Mouse
Result: negative
(OECD Test Guideline 429)
Germ cell mutagenicity
Ames test
Salmonella typhimurium
Result: negative
In vitro mammalian cell gene mutation test
Chinese hamster lung cells
Result: negative
Carcinogenicity
IARC: No ingredient of this product present at levels greater than or equal to 0.1% is
identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
Specific target organ toxicity - single exposure
Specific target organ toxicity - repeated exposure
Aspiration hazard

11.2 Additional Information

Not available

To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.

To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.
Hazardous properties cannot be excluded but are unlikely when the product is handled
appropriately.

Handle in accordance with good industrial hygiene and safety practice.

Stomach - Irregularities - Based on Human Evidence

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SECTION 12: Ecological information
12.1 Toxicity
Toxicity to fish static test EC50 - Danio rerio (zebra fish) - 6,4 mg/l - 96 h
(OECD Test Guideline 203)
Toxicity to daphnia EC50 - Daphnia magna (Water flea) - 15,4 mg/l - 48 h
and other aquatic Remarks: (ECHA)
invertebrates
Toxicity to algae static test NOEC - Pseudokirchneriella subcapitata (algae) - 2,1 mg/l
- 72 h
(OECD Test Guideline 201)
static test ErC50 - Pseudokirchneriella subcapitata (green algae) - 16
mg/l - 72 h
(OECD Test Guideline 201)
Toxicity to bacteria EC0 - E.coli - 500 mg/l
Remarks: (sodium salt)
(External MSDS)

12.2 Persistence and degradability

Biodegradability aerobic - Exposure time 28 d
Result: 91,5 % - Readily biodegradable.
(OECD Test Guideline 301F)
12.3 Bioaccumulative potential
12.4 Mobility in soil
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.
12.6 Other adverse effects

SECTION 13: Disposal considerations

13.1 Waste treatment methods
Product
See www.retrologistik.com for processes regarding the return of chemicals and
containers, or contact us there if you have further questions.

SECTION 14: Transport information

14.1 UN number
ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name
ADR/RID: Not dangerous goods
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 IMDG: Not dangerous goods
IATA: Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
14.4 Packaging group
ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user

Further information
Not classified as dangerous in the meaning of transport regulations.

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the
substance or mixture
This material safety data sheet complies with the requirements of Regulation (EC) No.
1907/2006.
National legislation
Seveso III: Directive 2012/18/EU of the European Parliament and of the Council on the
control of major-accident hazards involving dangerous substances.
Not applicable

15.2 Chemical Safety Assessment

For this product a chemical safety assessment was not carried out

SECTION 16: Other information

Further information
The above information is believed to be correct but does not purport to be all inclusive
and shall be used only as a guide. The information in this document is based on the
present state of our knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any guarantee of the properties of
the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any
damage resulting from handling or from contact with the above product. See
www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional
terms and conditions of sale.

Copyright 2020 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies
for internal use only.
The branding on the header and/or footer of this document may temporarily not visually
match the product purchased as we transition our branding. However, all of the
information in the document regarding the product remains unchanged and matches the
product ordered. For further information please contact [email protected].

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