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Doxofylline

Doxofylline is an antiasthmatic and COPD drug that works as both an adrenergic bronchodilator and phosphodiesterase inhibitor. It is administered 200 mg by NGT twice daily and works by increasing cyclic-3',5'-adenosine monophosphate levels to produce bronchodilation. It is indicated for bronchial asthma but is contraindicated in patients with acute MI, hypotension, lactation, or those allergic to it. Common adverse effects include tachycardia, palpitations, headache, and hyperglycemia. Nursing responsibilities are to monitor lung sounds, vital signs, and sputum before and during administration and observe for paradoxical bronchospasm
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0% found this document useful (0 votes)
390 views

Doxofylline

Doxofylline is an antiasthmatic and COPD drug that works as both an adrenergic bronchodilator and phosphodiesterase inhibitor. It is administered 200 mg by NGT twice daily and works by increasing cyclic-3',5'-adenosine monophosphate levels to produce bronchodilation. It is indicated for bronchial asthma but is contraindicated in patients with acute MI, hypotension, lactation, or those allergic to it. Common adverse effects include tachycardia, palpitations, headache, and hyperglycemia. Nursing responsibilities are to monitor lung sounds, vital signs, and sputum before and during administration and observe for paradoxical bronchospasm
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NAME AND DOSE, MECHANISM OF INDICATIONS CONTRAINDICATIONS ADVERSE NURSING

CLASSIFICATION FREQUENCY, ACTION EFFECT RESPONSIBILITY


OF DRUG ROUTE,
DURATION OF
ADMINISTRATION
Adrenergic Cardiac
Generic Name: 200 mg NGT BID bronchodilators and  Bronchial  Contraindicated for disorders:  Assess lung
Doxofylline phosphodiesterase asthma patients with Acute Tachycardia, sounds, pulse
inhibitors both MI, hypotension, and palpitation, and blood
Brand Names: work by increasing lactating patients extrasystole. pressure before
Ansimar intracellular level of Metabolism and administration
cyclic-3’,5’- adenosine nutrition an during peak
Classification: monophosphate(cAMP); disorder: of medication.
 Antiasthmatic & adrenergics by Hyperglycemia. Not amount,
COPD increasing production Gastrointestinal color, and
preparations and phosphodiesterase disorders: character of -
inhibitors by decreasing Nausea, sputum
breakdown. Increased vomiting, produced.
levels of cAMP produce abdominal pain,
bronchodilation. epigastric pain.  Monitor
Corticosteroids act by General pulmonary
decreasing airway disorders and function tests
inflammation. administrations: before
Irritability. initiating
Nervous system therapy and
disorders: periodically
Headache, during therapy
nervousness, to determine
dizziness. effectiveness of
Psychiatric medication.
disorders:  Observe for
Insomia, paradoxical
nervousness. bronchospasm
Renal and (wheezing). If
urinary conditions
disorders: occur, with
Albuminuria hold
medication and
notify
physician of
other health
care
professional
immediately

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