On Osteoporosis
On Osteoporosis
On Osteoporosis
RISK FACTORS :
PATHOPHYSIOLOGY :
PEAK BONE MASS
BONE REMODELLING
Peak bone mass the amount of bone tissue in the
skeleton,known as bone mass,can keep growing
until the late 20’s. At that point,bones have
reached maximum strength and density.
After peak bone mass is attained,both men
&women lose bone mass over the remainder of
their lifetime
BONE MODELLING-During growth skeleton increases
in size by apposition of new bone tissue on outer
surface of cortex.
BONE REMODELLING-Cellular process of bone activity
by which both cortical & cancellous bone are
maintained.
OSTEOPOROSIS Results from bone loss due to age
related changes in bone remodelling as well as
some extrinsic & intrinsic factors.
CLINICAL MANIFESTATIONS :
Osteoporosis has been usually called as “silent
disease”because bone mass is lost over many years with
no signs &symptoms.
Loss of height
Back pain
Vertebral collapse etc
DIAGNOSIS :
X-RAY STUDIES :Determine bone density
Radiographics : Bone mass[osteopenia]
Ultrasonography: Determine bone density
Dual energy X-ray absorptimetry[DEXA]
measures bone mineral density.
MANAGEMENT :