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Physiology of Digestion and

Absorption
By
Dr. Govand Sh Tawfeeq
Physiology II
1st Lecture
Sat. 3/2/2024
Overview of the Digestive System
The Digestive System Consists of :
a) Long hollow muscular tube or canal or tract called
gastrointestinal tract or (GIT):
◦ it is about 5 meters long
b) Accessory glands: include:
◦ Salivary glands
◦ Liver and gall bladder
◦ Pancreas
Overview of the Digestive System

• Oral cavity or mouth


• Pharynx
• Esophagus
• Stomach
• Small intestine
• Large intestine
• Rectum
• Anus
Main Functions of Digestive Tract
• 4 major activities of GI tract
1. Motility
• Propel ingested food from mouth toward rectum
2. Secretion of juices e.g. saliva
• Aid in digestion and absorption
3. Digestion
• Food broken down into absorbable molecules
4. Absorption
• Nutrients, electrolytes, and water are absorbed or
transported from lumen of GIT to blood stream
Motor Functions (Motility) of GIT
Motility of the GIT
1. Motility in the mouth
2 types :
a) Chewing or Mastication:
• It is reflex in nature
Significance:
1. Breaks the food into small pieces to be easily swallowed
2. Expose food to salivary amylase enzyme, which begins digestion of
starch
3. Help digestion of all types of food especially cellulose containing
food e.g. vegetables
Motility of the GIT

b) Swallowing:
Definition:
Swallowing is the transport of food
from mouth to stomach
Steps:
It consists of 3 phases or steps :
1) Buccal Phase: food is pushed
back into pharynx from mouth
b) Motility of the GIT
Swallowing:
2) Pharyngeal
Phase: food pass
through pharynx to
esophagus
b) Motility of the GIT
Swallowing
:
3) Oesophageal
Phase: food pass
through
esophagus to
stomach by
peristaltic
movements
Motility of GIT
2. Motility of Esophagus

• The esophagus is 25 cm.


• It is guarded by 2 sphincters :
1. Upper esophageal sphincter
prevents air from entering the GIT
2. Lower esophageal sphincter
prevents gastric contents from re-
entering the esophagus from the
stomach.
Motility of GIT
3. Motility of Stomach
• The stomach consists of fundus, body and
pylorus
• Proximal area (fundus and body) has a thin
wall and contracts weakly and infrequently →
holds large volumes of food (to store food)
because of receptive relaxation
• Distal area (pylorus) has thick wall with strong
and frequent peristaltic contractions that mix
and propel food into the duodenum.
• Also, distal area is responsible for gastric
emptying into duodenum
Motility of GIT
3. Motility of stomach

Gastric peristalsis
Thank You

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