This week, we will discuss the first iteration of KDIGO’s 2025 guidelines on ADPKD. These guidelines are a result of a decade of global collaboration between physicians, researchers, advocates, and patients. The guidelines incorporate ADPKD-specific care as well as many general CKD management practice points.
This week, we will celebrate in advance World Kidney Day by discussing the results of OBInutuzumab in active lupus nephritis. The LUNAR trial (rituximab versus placebo) was “almost” positive, but not quite there. Would Obi overpower its cousin ritux? ✨
This week, we will continue with February’s aldosterone leitmotif: do mineralocorticoid receptor antagonists (MRAs) truly blind the diagnostic in unilateral hypraldosteronism? Is this the article the mythbuster? Draw your own conclusions
This week, we will discuss the origins of primary hyperaldosteronism in normotensive patients. Could this undetected anomaly be the cause of idiopathic hypertension and CKD?
Joel Topf and Swapnil Hiremath never met in person until Swapnil stopped by Joel's poster on Saturday morning a couple of hours before NephJC Live. Edgar Lerma was there to document the moment.
NephJC is truly a 21st century project supported entirely by e-mail, DM, SMS and the occasional phone call.
The PubMed comment on #NephJC 14, T cells and Hypertension, has just been posted and can be viewed here. Thanks again to Matt Sparks @Nephro_Sparks for hosting such a sparkling discussion!
On Saturday at Kidney Week, just after the Late Breaking/High-Impact trials, NephJC held its first, in-real-life, journal club. Over 30 people trudged the mile from the convention center to the Double Tree where we did two short scientific presentations with discussions. Our first speaker, Dr. Wilson (@Nephrolalia) said it best when he said it was the first time he had given a talk where the ratio of presentation time to question and discussion time was 1:4.
This was important because we did not want NephJC live to be just another symposium where you listen to experts for the full hour. There is enough of that at the primary conference. The topics were hot, the speakers sharp and the discussion spirited.
Turn out was good with over 30 people coming to the event. Note that our best twitter discussion had 30 people.
Storify forthcoming.
As part of NephJC live we will be awarding social media awards. We will be giving recognition and prizes for:
If the use of social media has not rocketed you up the academic ranks, it is probably because you have no awards to show for it. Come to NephJC Live and get the recognition you deserve! Remember NephJC founders are not eligible for prizes.
The awards for social media will be decided by a blue ribbon panel made up by, our two speakers, Drs. Sawinsky and Wilson; our two founders, Drs. Topf and Swapnil; and Ivan Oransky and Kristina Fiore of MedPage Today.
We need submissions for best use of social media. So tweet links to examples with the hashtag #TNOT (Top nephrologist of twitter).
I had thought of starting a Nephrology Journal club ever since I wrote about eJC on PBFluids. In fact if you look at my suggestions for how to improve CJASN eJC, you will see the skeleton for the current #NephJC. But ideas are cheap and I never did anything about it.
In the middle of NephMadness last year I received a tweet from from Swapnil suggesting that someone do a Nephrology Twitter Journal Club. I told him it was a great idea but that I had my hands full with NephMadness and that he should write me after the contest ended.
Literally moments after we announced the winner of NephMadness, Swapnil e-mails me about the journal club. I told him to do some research on how twitter journal clubs work and write a post on Medium. I half hoped he would drop the ball and go away but he published it on April 17. A week later we collaborated on a tighter introduction, also published on Medium (we didn't yet have our SquareSpace sight) And five days after that we held our first NephJC.
We are indebted to Matt Sparks for both hosting the chat and compiling the Storify.
We are closing registration for NephJC Live this Sunday so register today if you want to be a part of the first NephJC Live event. We have two young investigators who will be sharing their data. We will be awarding the Social Media Awards for the best contributors to the conversation around Kidney Week and we will have lunch!
All the details are available here.
Register before it is too late!
We have covered a lot of subjects in our first half year but tomorrows study is unique. For the first time NephJC is going to tackle a basic science paper. In order to make this work we are bringing in a couple of ringers.
The article is a doozy, so make sure you do your homework. Help us make this very special basic-science episode of NephJC a success.
Swapnil Hiremath, is the co-founder of NephJC and his research was recently highlighted in Time Magazine, as in Time Man of the Year, Time Magazine. Awesome work, I can't wait to see his data at ASN Kidney Week. Way to go Swapnil!
If you are interested in the issue that Swapnil investigated, this article may provide some additional useful data.
UPDATE: Swapnil also made the ASN In the Loop e-mail blast on October 30. Wow.
