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    Preparatory Reaction-2

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    The preparatory reaction is the second step of cellular respiration that occurs in the mitochondria. It converts two three-carbon pyruvate molecules from glycolysis into two two-carbon acetyl-CoA molecules while reducing two NAD+ to NADH and releasing two carbon dioxide molecules. No ATP is generated in this step.

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    Preparatory Reaction-2

    Uploaded by

    api-327731714
    155 views2 pages
    The preparatory reaction is the second step of cellular respiration that occurs in the mitochondria. It converts two three-carbon pyruvate molecules from glycolysis into two two-carbon acetyl-CoA molecules while reducing two NAD+ to NADH and releasing two carbon dioxide molecules. No ATP is generated in this step.

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    The preparatory reaction is the second step of cellular respiration that occurs in the mitochondria. It converts two three-carbon pyruvate molecules from glycolysis into two two-carbon acetyl-CoA molecules while reducing two NAD+ to NADH and releasing two carbon dioxide molecules. No ATP is generated in this step.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    155 views2 pages

    Preparatory Reaction-2

    Uploaded by

    api-327731714
    The preparatory reaction is the second step of cellular respiration that occurs in the mitochondria. It converts two three-carbon pyruvate molecules from glycolysis into two two-carbon acetyl-CoA molecules while reducing two NAD+ to NADH and releasing two carbon dioxide molecules. No ATP is generated in this step.

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    of 2

    Preparatory Reaction

    Main idea: Converts 2 pyruvate to 2Acetyl-CoA.

    1. Preparatory Reaction is the second step in Cellular Respiration.


    It came after Glycolysis.
    2. It is also called Pyruvate Oxidation.
    3. It happens in the matrix of mitochondria.
    4. 2 Pyruvates, the products from glycolysis, which happened in
    cytoplasm have to enter the mitochondria to begin this

    process
    *Note that the diagram shows only one pyruvate but there are 2
    pyruvates that came from glycolysis so multiple by 2.

    5. Two pyruvate, a 3 carbon compound, is oxidized (loses electrons) to


    two Acetyl-CoA
    6. At the same time, 2 NAD+ is reduced to (gain electrons) 2 NADH. (1
    for each pyruvate)
    7. Because three carbon compound breaks down to two carbon
    compound, one carbon is released out of the mitochondria then out
    of the body as carbon dioxide. (2 CO2 released molecules, 1 for
    each pyruvate)
    8. Acetyl-CoA is a 2 carbon molecule that is attached to Coenzyme A.

    Net ATP Gain: None

    Net NADH Gain: 2 NADH (one for each pyruvate). Both NADH will go
    straight to the electron transport chain to be used to make more
    ATP.

    Net CO2 released: 2 CO2 molecules (one for each pyruvate)

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