BioChem Pinch Valve User Manual

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Solenoid Operated
Pinch Valves
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2
INDEX
Page 3 Pinch Valve General Information
Page 7 Silicone and C-Flex® Tubing Options

Spare tubing part numbers
Page 9 Pinch Valve Selection Guide
Page 10 Pinch Valve Part Numbering Conventions
Page 12 075-series Pinch Valves

Pinch valves for 1/16” (1.6mm) inner diameter tubing and smaller.
Page 18 100-series Pinch Valves

Pinch valves for 1/4” (6.3mm) inner diameter tubing and smaller.
Page 26 Position Feedback Sensor
Page 27 CoolCube Hit-and-Hold Circuit
Page 28 Controller
Page 29 Fittings and Connectors
Page 32 Mounting Accessories

3
PINCH VALVE GENERAL INFORMATION

What is a Pinch Valve?
The Bio-Chem Fluidics pinch valve is a solenoid-operated device. It is designed for opening and
closing tubing to achieve controlled fluid flow. When the solenoid is energized, the valve plunger
is retracted. This either opens the tubing (normally closed configuration) or closes the tubing
(normally open configuration). A valve in the 3-way configuration has both a normally open and a
normally closed flow path, which are operated simultaneously. When the solenoid is de-energized,
a spring returns the tubing back to its original open or closed position.
Why a Pinch Valve rather than an Isolation Valve?

Compared to an isolation valve that uses a diaphragm, the pinch valve has several distinctive
advantages:
 An unobstructed flow path with minimal pressure drop.
 Resistant to damage from particulates in the fluid stream.
 Ease of changing the wetted surfaces (i.e. the tubing for pinch valves) between operations.
 Easy sterilization of fluid path.
 No dead volume inside the valve.
FEATURES OF BIO-CHEM VALVE™ PINCH VALVES
Choice of tubing configurations.

The pinch valves are supplied with tubing already inserted in the valve:
 2-way valves: one 12-inch (30cm) tubing section.
 3-way valves: two 6-inch (15cm) tubing sections joined by a “Y” connector.
Dual tubing configurations (i.e. two tubes being operated simultaneously) are offered for smaller
tubing sizes. Multi-tube pinch valves with 4, 6 or 8 tubes and normally open operation are also
available.
4
2-way 3-way Dual 3-way
Choice of tubing materials.

Bio-Chem Fluidics offers two high-purity medical grade tubing materials for pinch valves:
 Platinum cured silicone tubing.
 C-Flex® tubing.
These tubing options have been specifically developed to withstand the rigors of usage with pinch
valves. The tubing will not stick shut even after prolonged closure. Excellent tubing memory
characteristics permit unencumbered flow when the valve is in the open position. In combination
with the Bio-Chem Valve pinch valves, both tubing options are rated for over 300,000 cycles.
It is also possible to use the pinch valves with tubing other than that supplied by Bio-Chem Fluidics.
In that case, Bio-Chem Fluidics will adjust the valve settings to meet the exact requirements of the
customer’s tubing.
Stroke set for each individual valve.

The stroke (i.e. the travel between the open and
closed positions) is individually set and tested
for each pinch valve. Through this process, we
ascertain:
 ~95% full flow in the open position.
 No leakage in the closed position at rated
pressures.
 Efficient valve operation with minimal
power usage and heat generation.
 Maximum tubing life.
Easy tube insertion.
The tubing entry area of the valve body is contoured to guide the tubing into
its seat.
Tubing securely seated.

The tubing is securely seated in a groove. The gap between the valve plunger
and the valve’s anvil is slightly smaller than the tubing’s outer diameter. The
tubing is held in place during operation without need for mechanical locking
features. Fluid flow and pressure drop are minimally affected, achieving
around 95% of full flow given the nominal tubing inner diameter.
5
Long life cycles.

Bio-Chem Valve™ pinch valves are designed to last for a minimum of 2 million open-and close
cycles. By choosing optional alternative body and plunger materials, the valve life can be extended
even further. Thanks to the precise stroke adjustment performed on each valve, we also optimize
the tubing life. Both the silicone and the C-Flex® tubing are rated for over 300,000 life cycles.
Continuous duty.
Bio-Chem Valve™ pinch valves can remain in the fully energized state indefinitely without damage
to the valve or the tubing.
Low power consumption and minimal heat generation.

The pinch valves’ efficient construction permits the use of low wattage solenoid coils, ranging from
2.8 Watt for 075-series valves to 8.0 Watt for 150-series valves. Heat generation is correspondingly
low. Both power usage and heat generation can be lowered further by stepping down the voltage
after actuation. With most of the pinch valves, voltage reduction of 66% is possible, reducing
power consumption by 89%.
Optional features, particularly for medical applications.
Override button for manual opening or closing

of tubing. This feature provides flow control in
the case of power loss. It also facilitates tubing
changes, especially when working with hard
tubing, such as Tygon®.
Pre-configured, factory-installed mounting flanges.

The flanges can be fixed so as to be on the inside or
the outside of the bulkhead. The customer can
choose the orientation of the mounting holes vis-à-vis
the tubing. The flanges are securely fixed to ensure
the valves permanent position despite of frequent
manipulation and tubing changes.
“Quiet” operation. Through the use of noise-dampening materials on internal valve components,
the noise generated at actuation of 075-series and 100-series pinch valves is reduced dramatically.
6
The noise level drops from approximately 72 dB to 52dB. This feature is recommended in noise-
sensitive environments, such as hospitals.
Position feedback sensor. An infra-red optical sensor

can be factory-mounted on the pinch valve. The sensor
detects the position of the valve pusher assembly. It
sends an electrical signal back to the controller
confirming the open or closed valve position.
PPS body material. For applications where the valve

body may come into contact with corrosive liquids,
chemically resistant glass-filled PPS material is available
for the valve body and plunger. Use of the PPS body
extends the valve life to 5 million cycles.
7
PINCH VALVE TUBING

A. Platinum-cured silicone tubing
1. Test Standards. The Bio-Chem Valve silicone tubing is tested in accordance to the standards set
by the United States Pharmacopoeia National Formulary XVII, 1990, Class VI Biological Test
for Plastics. It is FDA Masterfile listed (MAF 819).
2. Durability. This tubing has been selected for use with pinch valves. Platinum curing performed
on the tubing during the extrusion process imparts superior strength and durability. The
byproduct of this process, ethanol, is completely removed. The tubing has a low compression
set and will not stick shut even after prolonged periods in the closed position. Excellent
memory characteristics ensure full opening and unencumbered flow. The silicone tubing is
rated for 300,000 pinch valve cycles.
3. Sterilization. The silicone tubing can be sterilized through steam autoclaving, boiling, dry heat,
steam, and gamma radiation.
4. Gas permeability. Silicone tubing has a poor gas permeability rating.
Besides being already installed in the Bio-Chem Fluidics pinch valves, silicone tubing is also
available in 50-foot (15-meter) coils. The coils can be ordered under the part numbers listed below:
Diameter Pressure
Part number Inner Outer Minimum Maximum Length
10025-10S 0.010” / 0.25mm 0.093” / 2.36mm vacuum 30 psi / 2.0 bar 50 ft / 15m
10025-23S 0.023”/ 0.58mm 0.093” / 2.36mm vacuum 20 psi / 1.3 bar 50 ft / 15m
10025-01S 1/32” / 0.79mm 3/32” / 2.36mm vacuum 25 psi / 1.6 bar 50 ft / 15m
10025-50S 1/20” / 1.27mm 0.134” / 3.40mm vacuum 15 psi / 1.0 bar 50 ft / 15m
10025-02S 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 25 psi / 1.6 bar 50 ft / 15m
8
B. C-Flex® tubing
1. Test Standards. The C-Flex® tubing used on the Bio-Chem Valve pinch valves is tested in
accordance to the standards set by the United States Pharmacopoeia National Formulary XVII,
1990, Class VI Biological Test for Plastics. It is FDA Masterfile listed.
2. Material. The C-Flex® tubing material is a thermoplastic elastomer based on styrene-ethylene-
butylene. It does not contain leachable plasticizers.
3. Chemical compatibility. C-Flex® can be used with many acids and alkalis. It is not
recommended for use with oils and organic solvents.
4. Durability. This tubing has been selected for use with pinch valves. The tubing has a low
compression set and will not stick shut even after prolonged periods in the closed position.
Good memory characteristics ensure full opening and unencumbered flow. The C-Flex® tubing
is rated for 200,000 pinch valve cycles.
5. Sterilization. The C-Flex® tubing can be sterilized through steam autoclaving, ethylene oxide
(ETO), and gamma radiation.
6. Gas permeability. C-Flex® tubing has a fair gas permeability rating. It has lower gas
permeability than silicone.
Besides being already installed in the Bio-Chem Fluidics pinch valves, C-Flex® tubing is also
available in 50-foot (15-meter) coils. The coils can be ordered under the part numbers listed below:
Diameter Pressure
Part number Inner Outer Minimum Maximum Length
10025-23B 0.023”/ 0.58mm 0.093” / 2.36mm vacuum 20 psi / 1.3 bar 50 ft / 15m
10025-01B 1/32” / 0.79mm 3/32” / 2.36mm vacuum 25 psi / 1.6 bar 50 ft / 15m
10025-02B 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 25 psi / 1.6 bar 50 ft / 15m
9
PINCH VALVE SELECTION GUIDE

A. Valves with Bio-Chem Valve silicone or C-Flex® tubing installed
1. Select the tubing material – either silicone or C-Flex®. (See page 7 for additional information
about these tubing material options.)
2. Identify your required valve specifications among the following features:
a. Tubing internal diameter.
b. Flow configuration – normally open, normally closed, three-way or multi-tube.
c. Minimum and maximum pressure parameters.
3. Determine the valve type by looking up your combination of valve specifications in the tables
below.
Silicone Tubing
Internal Flow Configuration Min Max Valve
diameter 2-Way 2-Way 3-Way 2 or 3-Way Pressure Pressure Type
NC NO dual tube
0.010” / 0.25mm √ √ vacuum 30 psi / 2.0 bar
0.023”/ 0.58mm √ √ √ vacuum 20 psi / 1.3 bar
1/32” / 0.79mm √ √ √ vacuum 15 psi / 1.0 bar 075P
pg 11
1/20” / 1.27mm √ √ √ vacuum 15 psi / 1.0 bar
1/16” / 1.59mm √ √ √ 0 psi / 0 bar 15 psi / 1.0 bar
1/32” / 0.79mm √ √ √ √ vacuum 25 psi / 1.6 bar
1/16” / 1.59mm √ √ √ √ vacuum 25 psi / 1.6 bar
pg 12
3/16” / 4.76mm √ √ √ 0 psi / 0 bar 10 psi / 0.6 bar
1/4” / 6.35mm √ √ 0 psi / 0 bar 10 psi / 0.6 bar
1/4” / 6.35mm √ 0 psi / 0 bar 10 psi / 0.6 bar 150P pg 14
1/32” / 0.79mm 0 psi / 0 bar 15 psi / 1.0 bar 108P pg 15
√
Multi-tube
C-Flex® Tubing
Internal Flow Configuration Min Max Valve
diameter 2-Way 2-Way 3-Way 2 or 3-Way Pressure Pressure Type
NC NO dual tube
0.023”/ 0.58mm √ √ √ vacuum 20 psi / 1.3 bar
1/16” / 1.59mm √ √ √ 0 psi / 0 bar 15 psi / 1.0 bar pg 11
1/32” / 0.79mm √ √ √ √ vacuum 25 psi / 1.6 bar
1/16” / 1.59mm √ √ √ √ vacuum 25 psi / 1.6 bar 100P
1/8” / 3.18mm √ √ √ vacuum 20 psi / 1.3 bar pg 12
1/4” / 6.35mm √ √ 0 psi / 0 bar 10 psi / 0.6 bar
1/4” / 6.35mm √ 0 psi / 0 bar 10 psi / 0.6 bar 150P pg 14
1/32” / 0.79mm
√ 0 psi / 0 bar 15 psi / 1.0 bar 108P pg 15
Multi-tube
10
4. Turn to the appropriate page and select the valve based on the specification identified above and
additional attributes of your choice:
 Voltage(12 or 24 VDC)
 “Quiet” feature (optional)
 Mounting holes (optional)
 Mounting flange (optional)
 Position feedback sensor (optional)
 Manual override button (optional)
B. Valves for silicone or C-Flex® tubing to be installed by the customer

The Bio-Chem Fluidics valves can be purchased without the tubing installed. The customer can
then order the tubing separately and add the tubing at a later time.
For this option, follow the same valve selection process as outlined above. Then follow the part
number convention process for the determining the valve part number.
C. Valves for customer-specific tubing

If the customer intends to use the pinch valves with tubing other than Bio-Chem Fluidics-supplied
silicone or C-Flex® tubing, this requirement can be accommodated. The customer should provide a
sample of the tubing to Bio-Chem Fluidics, who will select the appropriate valve size and adjust the
stroke and force settings to match the tubing diameter and durometer.
Bio-Chem Fluidics will assign a special part number to this valve.
11
PINCH VALVE PART NUMBER CONVENTIONS

A. Single or dual tube pinch valves
The part numbers are constructed according to the following pattern:
1. Shell size corresponds to the diameter of the solenoid shell. Available sizes are 075P (3/4”
diameter), 100P (1.0” diameter) and 150P (1.5” diameter).
2. Flow path options are “2” (2-way), “3” (3-way), “D2” (dual 2-way), and “D3” (dual 3-way).
3. Flow configuration options are “NC” (normally closed), “NO” (normally open), and “MP” (3-
way with one port normally open and the other port normally closed).
4. Voltages offered are “12” (12 Vdc) and “24” (24 Vdc).
5. Tube size designators are assigned according to the following table:
Designator Inner diameter Outer diameter Silicone C-Flex®
-10 0.010” / 0.25mm 0.093” / 2.36mm √
-23 0.023”/ 0.58mm 0.093” / 2.36mm √ √
-01 1/32” / 0.79mm 3/32” / 2.36mm √ √
-50 1/20” / 1.27mm 0.134” / 3.40mm √
-02 1/16” / 1.59mm 1/8” / 3.18mm √ √
-03 1/16” / 1.59mm 3/16” / 4.76mm √ √
-04 3/16” / 4.76mm 1/4” / 6.35mm √
-05 1/8” / 3.18mm 1/4” / 6.35mm √ √
-06 1/4” / 6.35mm 3/8” / 9.52mm √ √
6. Tubing material options are “S” (silicone) and “B” (C-Flex®). In case the valve is to be
delivered without tubing, the material designating letter is replaced by a hash mark (“#“). The
tubing size designator must still be indicated as before.
7. Valve options can be designated by the following letters, which should be added in the sequence
indicated below:
4 – PPS body material.
Q – “quiet” valves, available for 075P and 100P normally closed valves.
M – mounting holes situated on the bottom of the valve body.
F – position feedback sensor.
K – manual override button, available for 075P and 100P valves without dual tubing.
When the manual override button is chosen, the “M” for mounting holes cannot be
selected.
L – factory-installed mounting flange, available for 075P and 100P valves. The flanges
will be installed at 90º to the tubing path.
When an option is not selected, the corresponding part number position is simply left
blank.
12
075P SERIES PINCH VALVES

For use with soft-walled tubing with inner diameters from 0.010”/0.25mm to 1/16”/1.59mm.
Features of standard 075P series pinch
valves.
Lead
 Continuous duty solenoid operated wires
valve. Can remain fully energized for
indefinite time period.
Solenoid
 Valve life above 2 million cycles. shell
 Precise stroke and closing force setting
to protect tubing and extend valve life. Body
 Chemically resistant PPS plunger and
ASA/PC body materials. Plunger
 15-inch (38cm) lead wires.
 Low power consumption (3.5 Watt or
less) and minimal heat generation. 3-way valve 2-way valve
A. Two-Way Normally closed valves

NOTE: For 24 VDC, replace 075P2NC12 with 075P2NC24 in any of the part numbers listed.
12 VDC valves with silicone tubing.

12-inch (30cm) strip of silicone tubing is installed in the valve.
Part No. Inner diameter Outer diameter Min pressure Max pressure Power at
21ºC
075P2NC12-10S 0.010” / 0.25mm 0.093” / 2.36mm vacuum 30 psi / 2.0 bar 3.5 Watt
075P2NC12-23S 0.023”/ 0.58mm 0.093” / 2.36mm vacuum 20 psi / 1.3 bar 2.8 Watt
075P2NC12-01S 1/32” / 0.79mm 3/32” / 2.36mm vacuum 15 psi / 1.0 bar 2.8 Watt
98302-00 already switched
98302-10 already switched 24 VDC
075P2NC12-50S 1/20” / 1.27mm 0.134” / 3.40mm vacuum 15 psi / 1.0 bar 2.8 Watt
075P2NC12-02S 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 15 psi / 1.0 bar 2.8 Watt
98302-02 already switched
98302-12 already switched 24 VDC
12 VDC valves with C-Flex® tubing.

12-inch (30cm) strip of C-Flex® tubing is installed in the valve.
21ºC
075P2NC12-10B 0.010” / 0.25mm 0.093” / 2.36mm vacuum 30 psi / 2.0 bar 3.5 Watt
13
075P2NC12-23B 0.023”/ 0.58mm 0.093” / 2.36mm vacuum 20 psi / 1.3 bar 2.8 Watt
075P2NC12-01B 1/32” / 0.79mm 3/32” / 2.36mm vacuum 15 psi / 1.0 bar 2.8 Watt
075P2NC12-50B 1/20” / 1.27mm 0.134” / 3.40mm vacuum 15 psi / 1.0 bar 2.8 Watt
075P2NC12-02B 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 15 psi / 1.0 bar 2.8 Watt
12 VDC valves without factory-installed tubing.

Valves can be used with Bio-Chem Fluidics supplied silicone or C-Flex® tubing.
Part No. Gapped for inner Gapped for outer Min pressure Max pressure Power at
diameter diameter 21ºC
075P2NC12-10# 0.010” / 0.25mm 0.093” / 2.36mm vacuum 30 psi / 2.0 bar 3.5 Watt
075P2NC12-23# 0.023”/ 0.58mm 0.093” / 2.36mm vacuum 20 psi / 1.3 bar 2.8 Watt
075P2NC12-01# 1/32” / 0.79mm 3/32” / 2.36mm vacuum 15 psi / 1.0 bar 2.8 Watt
075P2NC12-50# 1/20” / 1.27mm 0.134” / 3.40mm vacuum 15 psi / 1.0 bar 2.8 Watt
075P2NC12-02# 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 15 psi / 1.0 bar 2.8 Watt
B. Two-Way Normally open valves
NOTE: For 24 VDC, replace 075P2NO12 with 075P2NO24 in any of the part numbers listed.

21ºC
075P2NO12-10S 0.010” / 0.25mm 0.093” / 2.36mm vacuum 30 psi / 2.0 bar 3.5 Watt
075P2NO12-23S 0.023”/ 0.58mm 0.093” / 2.36mm vacuum 20 psi / 1.3 bar 2.8 Watt
075P2NO12-01S 1/32” / 0.79mm 3/32” / 2.36mm vacuum 15 psi / 1.0 bar 2.8 Watt
98302-20 switch Apr 2010
98302-30 switch Apr 2010 24 VDC
075P2NO12-50S 1/20” / 1.27mm 0.134” / 3.40mm vacuum 15 psi / 1.0 bar 2.8 Watt
075P2NO12-02S 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 15 psi / 1.0 bar 2.8 Watt
98302-22 switch Apr 2010
98302-32 switch Apr 2010 24 VDC

21ºC
075P2NO12-10B 0.010” / 0.25mm 0.093” / 2.36mm vacuum 30 psi / 2.0 bar 3.5 Watt
075P2NO12-23B 0.023”/ 0.58mm 0.093” / 2.36mm vacuum 20 psi / 1.3 bar 2.8 Watt
075P2NO12-01B 1/32” / 0.79mm 3/32” / 2.36mm vacuum 15 psi / 1.0 bar 2.8 Watt
075P2NO12-50B 1/20” / 1.27mm 0.134” / 3.40mm vacuum 15 psi / 1.0 bar 2.8 Watt
075P2NO12-02B 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 15 psi / 1.0 bar 2.8 Watt
14

075P2NO12-10# 0.010” / 0.25mm 0.093” / 2.36mm vacuum 30 psi / 2.0 bar 3.5 Watt
075P2NO12-23# 0.023”/ 0.58mm 0.093” / 2.36mm vacuum 20 psi / 1.3 bar 2.8 Watt
075P2NO12-01# 1/32” / 0.79mm 3/32” / 2.36mm vacuum 15 psi / 1.0 bar 2.8 Watt
075P2NO12-50# 1/20” / 1.27mm 0.134” / 3.40mm vacuum 15 psi / 1.0 bar 2.8 Watt
075P2NO12-02# 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 15 psi / 1.0 bar 2.8 Watt
C. Three-way valves (one port normally open, other port normally closed)
NOTE: For 24 VDC, replace 075P3MP12 with 075P3MP24 in any of the part numbers listed.

Two 6-inch (15cm) strips of silicone tubing joined by ‘Y’ connector installed in the valve.
21ºC
075P3MP12-23S 0.023”/ 0.58mm 0.093” / 2.36mm vacuum 20 psi / 1.3 bar 2.8 Watt
075P3MP12-01S 1/32” / 0.79mm 3/32” / 2.36mm vacuum 15 psi / 1.0 bar 2.8 Watt
98302-40 switch July 2010
98302-48 switch July 2010 24 VDC
075P3MP12-50S 1/20” / 1.27mm 0.134” / 3.40mm vacuum 15 psi / 1.0 bar 2.8 Watt
075P3MP12-02S 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 15 psi / 1.0 bar 2.8 Watt

Two 6-inch (15cm) strips of C-Flex® tubing joined by ‘Y’ connector installed in the valve.
21ºC
075P3MP12-23B 0.023”/ 0.58mm 0.093” / 2.36mm vacuum 20 psi / 1.3 bar 2.8 Watt
075P3MP12-01B 1/32” / 0.79mm 3/32” / 2.36mm vacuum 15 psi / 1.0 bar 2.8 Watt
075P3MP12-50B 1/20” / 1.27mm 0.134” / 3.40mm vacuum 15 psi / 1.0 bar 2.8 Watt
075P3MP12-02B 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 15 psi / 1.0 bar 2.8 Watt
15

075P2NO12-23# 0.023”/ 0.58mm 0.093” / 2.36mm vacuum 20 psi / 1.3 bar 2.8 Watt
075P2NO12-01# 1/32” / 0.79mm 3/32” / 2.36mm vacuum 15 psi / 1.0 bar 2.8 Watt
075P2NO12-50# 1/20” / 1.27mm 0.134” / 3.40mm vacuum 15 psi / 1.0 bar 2.8 Watt
075P2NO12-02# 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 15 psi / 1.0 bar 2.8 Watt
D. Options
1. Glass-filled PPS body material (suffix = “4”). Changing the body material from ASA/PC to PPS
provides two advantages:
a. Enhanced chemical resistance in the case of spills onto the body or when using aggressive
cleaning agents on the valves.
b. Longer cycle life, extending the valve life cycles from 2 million to 5 million.
2. “Quiet” operation (suffix = “Q”). Implementing the “quiet” option reduces the valve noise level
from about 72 dB to about 52 dB. The “quiet” option is available for:
a. 075P2NC-way normally closed valves.
b. 075P2NO-way normally open valves.
The “quiet” option cannot be used on 075P3MP three-way valves. The noise level of the 3-way
valves is inherently attenuated by tubing dampening the motion in both directions.
3. Mounting holes (suffix = “M”) situated on
the bottom of the valve body (i.e. the plastic).
The dimensions are as follows:
a. A (thread) = #2-56
b. B = 0.50 inches / 12.7mm center-to-center
c. C = 0.125 inches / 3.2mm
The mounting holes cannot be used in
combination with the manual override button.
4. Position feedback sensor (suffix = “F”). The feedback sensor can be mounted on 075P pinch
valves in the normally closed and the three-way configurations. (Please see page XX for details
about this option.)
5. Manual override button (suffix = “K”). The manual

override button is available for all 2-way and 3-way valve
configurations. Its uses include:
a. Flow control for emergencies during electric power loss.
b. To facilitate tubing changes.
16
6. Factory-installed mounting flange (suffix = “L”). The

mounting flanges are available for all 075P pinch valve
configurations. They will be installed at a 90º angle to the
tubing with the orientation to the outside of the bulkhead.
a. 30% glass-filled polypropylene material provides secure
fit.
b. Can be cleaned with alcohol, bleaches and other
cleaning agents.
c. White color.
d. Distance between mounting hole centers = 1.25” /
3.2cm.
e. The flanges can be installed at angles other than 90º to
the tubing and/or with orientation to the inside of the
bulkhead upon request.
This mounting flange can be purchased as a stand-alone
item under part number MFP-075. Please see page XX for
details.
E. “Hit and Hold” voltage reduction

Within 100 ms of valve actuation, the voltage required to hold the valve in position can be reduced. The
voltage step-down results in the dual benefits of power conservation and heat reduction. The amount of
the voltage reduction possible is 66% (i.e. 24 Vdc to 8 Vdc or 12 Vdc to 4 Vdc) for all 075P pinch valves
that do not incorporate the “quiet” feature. This results in a power usage / heat generation drop of 89%.
The 66% voltage reduction can be accomplished using the Bio-Chem Fluidics CoolCube-R hit-and-hold
circuit. Please see page XX for details.
For the 075P pinch valves with the “quiet” feature, voltage can be reduced by 33% (i.e. 24 Vdc to 16
Vdc and 12 Vdc to 8 Vdc) after 100 ms for a power usage drop of 55%.
F. Dimensions
075P2NC Normally Closed 2-Way Pinch Valve

17
075P2NC Normally Open 2-Way Pinch Valve
075P3MP 3-Way Pinch Valve

18
100P SERIES PINCH VALVES

For use with soft-walled tubing with inner diameters from 1/32” / 0.79mm to 1/4” / 6.35mm.
Features of standard 100P series pinch valves.
 Continuous duty solenoid operated valve. Lead wires
Can remain fully energized for indefinite time
period.
 Valve life above 2 million cycles. Solenoid shell
 Precise stroke and closing force setting to
protect tubing and extend valve life. Body
 Chemically resistant PPS plunger and
ASA/PC body materials. Plunger
 15-inch (38cm) lead wires.
 Low power consumption (mostly 4.0 Watt) 2-way valve 3-way valve
and minimal heat generation.
A. Two-Way Normally closed valves

NOTE: For 24 VDC, replace 100P2NC12 with 100P2NC24 in any of the part numbers listed.

21ºC
19

21ºC

B. Two-Way Normally open valves

NOTE: For 24 VDC, replace 100P2NO12 with 100P2NO24 in any of the part numbers listed.
20

21ºC
98302-24 switch April 2010
98302-34 switch April 2010 24 VDC

21ºC
21

C. Three-way valves (one port normally open, other port normally closed)
NOTE: For 24 VDC, replace 100P3MP12 with 100P3MP24 in any of the part numbers listed.

Two 6-inch (15cm) strips of silicone tubing joined by ‘Y’ connector installed in the valve.
21ºC

Two 6-inch (15cm) strips of C-Flex® tubing joined by ‘Y’ connector installed in the valve.
21ºC
22

100P3MP12-01# 1/32” / 0.79mm 3/32” / 2.36mm vacuum 25 psi / 1.6 bar 4.0 Watt
100P3MP12-02# 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 25 psi / 1.6 bar 4.0 Watt
100P3MP12-04# 3/16” / 4.76mm 1/4” / 6.35mm 0 psi / 0 bar 10 psi / 0.6 bar 8.0 Watt
D. Valves with Dual Tubing

For use with soft-walled tubing with inner diameters of1/32” / 0.79mm and 1/16” / 1.59mm.
Features of standard 100PD series dual-tubing
pinch valves are identical to those of single-
tubing pinch valves except:
 The body and plunger material is Acetal.
 There are two sets of tubing in every
valve.
NOTE: For 24 VDC, replace 100PD---12 with 100PD---24 in any of the part numbers listed.

2-Way: 12-inch (30cm) strip of silicone tubing is installed in the valve.
3-Way: Two 6-inch (15cm) strips of silicone tubing joined by ‘Y’ connector installed in the valve.
Configuration Part No. Inner diameter Outer diameter Min Max pressure Power at
pressure 21ºC
2-Way normally 100PD2NC12-01S 1/32” / 0.79mm 3/32” / 2.36mm vacuum 25 psi / 1.6 bar 4.0 Watt
closed 100PD2NC12-02S 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 25 psi / 1.6 bar 4.0 Watt
2-Way normally 100PD2NO12-01S 1/32” / 0.79mm 3/32” / 2.36mm vacuum 25 psi / 1.6 bar 4.0 Watt
open 100PD2NO12-02S 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 25 psi / 1.6 bar 4.0 Watt
100PD3MP12-01S 1/32” / 0.79mm 3/32” / 2.36mm vacuum 25 psi / 1.6 bar 8.0 Watt
3-Way
100PD3MP12-02S 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 25 psi / 1.6 bar 8.0 Watt
23

pressure 21ºC
2-Way normally 100PD2NC12-01B 1/32” / 0.79mm 3/32” / 2.36mm vacuum 25 psi / 1.6 bar 4.0 Watt
closed 100PD2NC12-02B 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 25 psi / 1.6 bar 4.0 Watt
2-Way normally 100PD2NO12-01B 1/32” / 0.79mm 3/32” / 2.36mm vacuum 25 psi / 1.6 bar 4.0 Watt
open 100PD2NO12-02B 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 25 psi / 1.6 bar 4.0 Watt
100PD3MP12-01B 1/32” / 0.79mm 3/32” / 2.36mm vacuum 25 psi / 1.6 bar 8.0 Watt
3-Way
100PD3MP12-02B 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 25 psi / 1.6 bar 8.0 Watt

pressure 21ºC
2-Way normally 100PD2NC12-01# 1/32” / 0.79mm 3/32” / 2.36mm vacuum 25 psi / 1.6 bar 4.0 Watt
closed 100PD2NC12-02# 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 25 psi / 1.6 bar 4.0 Watt
2-Way normally 100PD2NO12-01# 1/32” / 0.79mm 3/32” / 2.36mm vacuum 25 psi / 1.6 bar 4.0 Watt
open 100PD2NO12-02# 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 25 psi / 1.6 bar 4.0 Watt
100PD3MP12-01# 1/32” / 0.79mm 3/32” / 2.36mm vacuum 25 psi / 1.6 bar 8.0 Watt
3-Way
100PD3MP12-02# 1/16” / 1.59mm 1/8” / 3.18mm 0 psi / 0 bar 25 psi / 1.6 bar 8.0 Watt
E. Options
1. Glass-filled PPS body material (suffix = “4”). (Not available for dual-tubing valves.) Changing the
body material from ASA/PC to PPS provides two advantages:
a. Enhanced chemical resistance in the case of spills onto the body or when using aggressive cleaning
agents on the valves.
b. Longer cycle life, extending the valve life cycles from 2 million to 5 million.
2. “Quiet” operation (suffix = “Q”). Implementing the “quiet” option reduces the valve noise level from
about 72 dB to about 52 dB. The “quiet” option is available for:
a. 100P2NC-way normally closed valves.
b. 100P2NO-way normally open valves.
The “quiet” option cannot be used on 100P3MP three-way valves. The noise level of the 3-way valves is
inherently attenuated by tubing dampening the motion in both directions.
24
3. Mounting holes (suffix = “M”) situated on the bottom

of the valve body (i.e. the plastic). The dimensions are
as follows:
1. A (thread) = #4-40
2. B = 0.687 inches / 17.5mm center-to-center
3. C = 0.218 inches / 5.54mm
The mounting holes cannot be used in combination with
the manual override button.
4. Position feedback sensor (suffix = “F”). The feedback sensor can be mounted on 075P pinch valves in
the normally closed and the three-way configurations. (Please see page XX for details about this option.)
5. Manual override button (suffix = “K”). The manual override

button is available for all 2-way and 3-way valve configurations
except for dual-tubing valves. Its uses include:
a. Flow control for emergencies during electric power loss.
b. To facilitate tubing changes.
6. Factory-installed mounting flange (suffix = “L”). The

mounting flanges are available for all 100P pinch valve
configurations. They will be installed at a 90º angle to the
tubing with the orientation to the outside of the bulkhead.
a. 30% glass-filled polypropylene material provides secure
fit.
b. Can be cleaned with alcohol, bleaches and other
cleaning agents.
c. White color.
d. Distance between mounting hole centers = 1.56” /
3.97cm. The footprint is identical as that of Sirai pinch
valves.
e. The flanges can be installed at angles other than 90º to
the tubing and/or with orientation to the inside of the
bulkhead upon request.
This mounting flange can be purchased as a stand-alone
item under part number MFP-100. Please see page XX for
details.
F. “Hit and Hold” voltage reduction

Within 100 ms of valve actuation, the voltage required to hold the valve in position can be reduced. The
voltage step-down results in the dual benefits of power conservation and heat reduction. The amount of the
voltage reduction possible is:
 66% (i.e. 24 Vdc to 8 Vdc or 12 Vdc to 4 Vdc) for all 100P pinch valves that do not incorporate the
“quiet” feature. This results in a power usage / heat generation drop of 89%.
 50% (i.e. 24 Vdc to 12 Vdc or 12 Vdc to 6 Vdc) for all 100P pinch valves with the “quiet” feature.
This results in a power usage / heat generation drop of 75%.
The voltage reduction can be accomplished using the Bio-Chem Fluidics CoolCube hit-and-hold circuit.
Please see page XX for details.
25
G. Dimensions
100P2NC Normally Closed 2-Way Pinch Valve
100P2NO Normally Open 2-Way Pinch Valve
100P3MP 3-Way Pinch Valve

26
OPTICAL POSITION FEEDBACK SENSOR

Position feedback is provided through a compact, factory-mounted infrared optical sensor that
instantaneously detects the position of the pinch valve pusher/armature assembly. An electrical
signal is transmitted back to the instrument control system, confirming whether the valve is open or
closed. With no moving parts, the optical sensor has a virtually unlimited life. The position
feedback sensor is an essential feature in many critical operations, such as in life-sustaining medical
applications.
A. Design and dimensions.
B. Feedback sensor installation in the instrument

1. Electrical specifications:
Input voltage: 5.0 VDC
Maximum output voltage: 30.0 VDC
Maximum output current: 40.0 mA
Proper valve function is indicated by a drop in feedback voltage when the valve is open.
2. Installation:
a. Connect sensor leads, Red (+) and Black (-), to a 5 VDC power supply.
b. Connect the valve leads, Brown (+) and Blue (-), to a 12 VDC or 24 VDC power supply
as indicated on the valve label.
c. Connect the signal lead, White (+), to a positive rail via the appropriate resistor. The
feedback voltage and pull-up resistor will depend on the electrical load in the system.
3. Typical setup diagram:
27
CoolCube™ “Hit and Hold” Circuit

Features of the CoolCube™.
 Steps down DC voltage through pulse width
modulation after 100 ms.
 Reduces power consumption and heat generation
while in “hold” setting.
 Permits faster response and longer stroke through
brief use of voltage above valve nominal rating.
 No power storage. Valve turns off immediately
when power is cut to the circuit.
 Terminal pins for easy in-line installation.
A. Specifications
CoolCube-R CoolCube-50
01356-52
Time from “hit” to “hold” voltage: 100 ms 100 ms
Voltage step-down percentage: 67% 50%
Maximum input voltage: 36 VDC 36 VDC
Maximum input current: 1 amp 1 amp
“Hold” voltage with 36 VDC input: 12 VDC 18 VDC
Power consumption reduction: 89% 75%
B. Installation
1. Connect to DC power supply using AMP™, Molex® or similar connector. Respect polarity.
2. Connect to valve lead wires using AMP™, Molex® or similar connector. No polarity requirement.
3. Turn on the power supply.
C. Dimensions
28
FlowTest™
Automated controller for micro-fluidic systems
FlowTest™ is an automated controller that operates up to eight
fluidic control devices (FCD’s, such as solenoid valves and
pumps), each of which can be run in parallel or independently.
Programming is carried out using the dedicated CosDesigner™
software running on a PC or a laptop computer. Multiple
programs can be set up, stored and managed. The fields of use
include laboratory and industrial applications requiring precise
liquid transfers, sampling and injection.
FlowTest™ can also operate as a stand-alone instrument, without
a computer. In this mode, programs are loaded using a USB
key. The controller is operated by “run” and “stop” buttons
conveniently located on top of the control unit.
A. Technical specifications
Dimensions: 22 x 18 x 8.5 cm / 9 x 7 x 3.5 inches
Capacity: Up to 8 valves and pumps running in parallel.
Output voltage: 12 V or 24 V
External trigger: 4 IRQ’s (0-5V TTL, dry contact) permitting the start or stop of valve or pump
operation. IRQ inputs through female CINCH/AV connectors.
FCD connection: Spring-loaded terminal blocks with bi-color LED’s indicating state of actuation.
USB-A port: Designated for USB key for loading programs into controller. A USB key
loaded with the Bio-Chem Fluidics database is supplied with the controller.
USB-B port: Designated for PC or laptop connection.
Input voltage: 110-120 V, 60 Hz / 220-240 V, 50 Hz. Power cables with U.S. and European
plugs are supplied with the controller.
Programming: CosDesigner™ tool can be run on Windows Vista and Windows XP operating
systems in either 32-bit or 64-bit versions.
B. Characteristics of the main screen of the CosDesigner™ software

Graphic window for micro-fluidic diagrams.
Library of fluid system

components, incl.
valves and pumps.
Visualization of the Pulse
Preview window used Width Modulation (PWM)
to pan and zoom signals for each FCD.
around the graphic
window.
Table of FCD’s and their

technical characteristics.
Visualization of program sequence.

29
BARBED FITTINGS
Adaptors for soft-walled tubing to ¼”-28 threaded ports.
A. DIBA Click-N-Seal™ Barbed Adaptors

Click-N-Seal barbed fittings allow you to
feel and hear that the fitting is properly
installed. When the correct torque is
reached, the cap emits an audible click.
The fitting itself does not tighten beyond
the torque limit. Both the port and the
fitting are protected from over-tightening
and cannot be stripped.
The wetted material is polycarbonate.
Part No. Tubing inner Thread Cap color

diameter
008NB16-CS5R 1/16” / 1,6mm Male ¼”-28 Red
008NB32-CS5R 1/8” / 3.2mm Male ¼”-28 Red
008NB40-CS5R 5/32” / 4.0mm Male ¼”-28 Red
B. OMNIFIT® ¼”-28 Thread to Barbed Adaptors

Omnifit® barbed adaptors are designed for use
with soft wall tubing. Machined from
chemically resistant PEEK™
(polyetheretherketone) or Acetal material,
they have a superior barb with a crisp edge
that retains tubing more securely than molded
adaptors.
The PEEK fittings have a natural brown color
and the Acetal fittings are white.
30
Female ¼”28 thread to barbed adaptors in PEEK and Acetal
PEEK fitting Acetal fitting Tubing inner

Part No. Part No. diameter
008NB10-KD2L 008NB10-AD2B 0.039” / 1.0mm
06463-61
008NB15-KD2L 008NB15-AD2B 1/16” / 1.5mm
06463-62
008NB20-KD2L 008NB20-AD2B 0.79” / 2.0mm
06463-63
008NB25-KD2L 008NB25-AD2B 1.0” / 2.5mm
06463-64
008NB32-KD2L 008NB32-AD2B 1/8” / 3.2mm
06463-65
Male ¼”28 thread to barbed adaptors in PEEK and Acetal
PEEK fitting Acetal fitting Tubing inner

Part No. Part No. diameter
008NB10-KD5L 008NB10-AD5B 0.039” / 1.0mm
06463-51
008NB15-KD5L 008NB15-AD5B 1/16” / 1.5mm
06463-52
008NB20-KD5L 008NB20-AD5B 0.79” / 2.0mm
06463-53
008NB25-KD5L 008NB25-AD5B 1.0” / 2.5mm
06463-54
008NB32-KD5L 008NB32-AD5B 1/8” / 3.2mm
06463-55
008NB40-KD5L 008NB40-AD5B 5/32” / 4.0mm
06463-56
008NB60-KD5L 008NB60-AD5B 1/4” / 6.0mm
06463-57
008NB80-KD5L 008NB80-AD5B 5/16” / 8.0mm
06463-58
31
C. Polypropylene tubing connectors

32
MOUNTING OPTIONS
A. MFP-075 and MFP-100 Mounting Flanges
1. Features
 30% glass-filled polypropylene material.
 Spring steel retainer and set screw ensure
secure fit.
 Can be cleaned with alcohol, bleaches and
other cleaning agents.
 White color.
 Can be mounted on inside or outside of
bulkhead.
 Angle relative to tubing entirely adjustable.
2. Installation
 Option 1: factory installed in the position requested by the customer (part number suffix “L”).
Security of the flange position is enhanced through a dowel pin inserted into the metal valve shell.
 Option 2: installed by customer facing inside or outside of bulkhead at desired angle to tubing.
3. Dimensions
MFP075 MFP100
33
B. Spring Steel Mounting Clip, Polyethylene Mounting Flange, Aluminum

Mounting Ring

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Page 3 Pinch Valve General Information

Page 7 Silicone and C-Flex® Tubing Options

Page 9 Pinch Valve Selection Guide

Page 10 Pinch Valve Part Numbering Conventions

Page 12 075-series Pinch Valves

Page 18 100-series Pinch Valves

Page 26 Position Feedback Sensor

Page 27 CoolCube Hit-and-Hold Circuit

Page 29 Fittings and Connectors

Page 32 Mounting Accessories

PINCH VALVE GENERAL INFORMATION

Why a Pinch Valve rather than an Isolation Valve?

FEATURES OF BIO-CHEM VALVE™ PINCH VALVES

Choice of tubing configurations.

2-way 3-way Dual 3-way

Choice of tubing materials.

Stroke set for each individual valve.

Tubing securely seated.

Long life cycles.

Low power consumption and minimal heat generation.

Optional features, particularly for medical applications.

Override button for manual opening or closing

Pre-configured, factory-installed mounting flanges.

Position feedback sensor. An infra-red optical sensor

PPS body material. For applications where the valve

PINCH VALVE TUBING

PINCH VALVE SELECTION GUIDE

B. Valves for silicone or C-Flex® tubing to be installed by the customer

C. Valves for customer-specific tubing

PINCH VALVE PART NUMBER CONVENTIONS

075P SERIES PINCH VALVES

A. Two-Way Normally closed valves

12 VDC valves with silicone tubing.

12 VDC valves with C-Flex® tubing.

12 VDC valves without factory-installed tubing.

12 VDC valves with silicone tubing.

12 VDC valves with C-Flex® tubing.

12 VDC valves without factory-installed tubing.

12 VDC valves with silicone tubing.

12 VDC valves with C-Flex® tubing.

12 VDC valves without factory-installed tubing.

5. Manual override button (suffix = “K”). The manual

6. Factory-installed mounting flange (suffix = “L”). The

E. “Hit and Hold” voltage reduction

075P2NC Normally Closed 2-Way Pinch Valve

075P2NC Normally Open 2-Way Pinch Valve

075P3MP 3-Way Pinch Valve

100P SERIES PINCH VALVES

A. Two-Way Normally closed valves

12 VDC valves with silicone tubing.

12 VDC valves with C-Flex® tubing.

12 VDC valves without factory-installed tubing.

B. Two-Way Normally open valves

12 VDC valves with silicone tubing.

12 VDC valves with C-Flex® tubing.

12 VDC valves without factory-installed tubing.

12 VDC valves with silicone tubing.

12 VDC valves with C-Flex® tubing.