Naproxen Sodium Drug Study

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Dosage,

Route,
Name of Mechanism of Adverse Special
Frequency Indication Nursing Responsibilities
Drug Action Reactions Precautions
and
Timing

Generic: Dosage: As with other non- Symptomatic relief of Angioneurotic Increased risk of Observe 10 rights of drug
selective NSAIDs, rheumatoid arthritis, edema, menstrual serious CV administration.
Naproxen 550 mg/tab naproxen exerts it's osteoarthritis, disorders, pyrexia, thrombotic events.
sodium clinical effects by ankylosing Be aware that patient may
Route: infection, sepsis,
blocking COX-1 and spondylitis, tendinitis, MI and stroke. be at increased risk for CV
Brand: COX-2 enzymes acute gout, anaphylactic/anaph
PO ylactoid reactions, event, GI bleeding; monitor
leading to decreased headache, and HTN or worsening of
Skelan death. accordingly.
Frequency: prostaglandin migraine. pre-existing HTN.
synthesis.3 Although
Classificati Fluid retention and Advise patient to
1 tab BID both enzymes Contraindications Side Effects
on contribute to edema. remain up-right for 30
Timing: prostaglandin minutes after administration.
Functional: Hypersensitivity to Headache, ringing History of ulcer
production, they Give with food or after
BID after naproxen NA, aspirin in the ears,
Nonsteroidal have unique disease or GI meals if GI upset occurs.
meals (8 or other NSAIDs. tiredness, changes
functional bleeding.
Anti- History of peptic/GI
am and 6 differences.3 The in vision,
inflammatory ulcers, chronic Arrange for periodic
pm) for 15 COX-1 enzymes is drowsiness, Impaired renal
Drug; dyspepsia, bleeding ophthalmologic examination
days constitutively active dizziness function,
Antirheumati or perforation related during long-term therapy.
and can be found in hypovolemia, heart
to previous NSAID
c product normal tissues such failure, liver
therapy; recurrent If overdose occurs, institute
as the stomach
Chemical: peptic dysfunction, salt emergency procedures—
lining, while the COX-
ulcer/hemorrhage depletion. gastric lavage, induction of
2 enzyme is inducible
sodium;(2S)- unrelated to previous emesis, supportive therapy.
and produces
2-(6- NSAID therapy. Advanced renal
prostaglandins that
Severe renal, hepatic disease.
methoxynap mediate pain, fever
or cardiac failure.
hthalen-2- and inflammation.
Perioperative pain in Preexisting asthma.
yl)propanoat CABG surgery.
Drug Bank Online
e Pregnancy (last
(2020)
trimester).

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