Department of Veterinary

HAWASSA UNIVERSITY Medicine

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Department: Veterinary Medicine

Module Title: Biochemistry and Molecular Module Code: 02
Biology Module Credit: 20
Course Tile: Organic Chemistry Course Code: VetM 2023
Course Credit: 5 ECTS
Instructor Name: TBA

Instructor’s Contact Information: Course Information:

Office Academic
Phone: Semester:
Email: Meeting day:
Office Hours: Meeting time:
Meeting location:

1. Course Description:
Lecture: This course is designed to equip students with the structure and its relation to
properties, reactions and reaction mechanism. Both aliphatic and aromatic compounds are
studied along with an introduction to stereochemistry and conformational analysis.
Moreover, the different functional groups occurring in natural compounds will be studied in
connection with the common reactions they undergo. Later on ring structure of organic
compounds with biological importance will be discussed along with the chemistry of
naturally occurring (Bio)-organic compounds; Nomenclature, Physical and chemical
property, function, separation and identification.
Practical: The laboratory experience includes synthesis of a variety of organic compounds
with an emphasis on basic laboratory techniques.

2. Course Goals or Learning Outcome:

At the end of the course the students will be able to:

1. Explain the structure, physiochemical properties and functions of natural compounds.

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 2. Practice the general methods employed in the separation, identification and detection of
Biomolecules.
3. Identify the different functional groups and ring structures of organic compounds with
biological importance.
4. Use organic chemistry to their professional needs and as background for other courses.

3. Prerequisites:

None

4. Required text and references:

1. J. Mc Murry, Organic Chemistry, 5th edition, 2001, Thomson Asia Pte. Ltd.
2. Francis A. Carey, Organic Chemistry, 4th edition, 2000, The McGraw-Hill companies,
Inc.
3. Solomons G. T. W, Organic Chemistry, 5th edition, John Wiley & Sons, Inc.
4. Wade, L. G., Organic Chemistry, 1987, Prentice Hall, Inc.
5. F.M. Menger, D.J. Goldsmith; L. Mandle, Organic chemistry: A Concise Approach, 2nd
Ed., 1974
6. Ermias Dagne. Experiments in organic Chemistry I: Addis Ababa University; 1978
7. Wendimagegn Mammo. Practical Organic Chemistry II Laboratory manual: Addis
Ababa University; 1996.

5. Expectations:

 Students are expected to attend every class and participate in class room discussions, and
expected to create conducive environment for learning.
 Students are expected to do all assignments, homework and group works honestly and
encouraged to discuss with classmates.
 Students are expected to attend every laboratory section and attendance is compulsory and
will be marked.
 Students are expected to read the lab manual a head of every experiment and have to prepare
flowchart.
 Students are expected to do all lab reports for each laboratory activity and the lab report will
be marked.

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 Students are expected to be honest and honorable during the laboratory work and expected to
strictly follow the laboratory safety rules and the procedures provided by the instructor or
laboratory text book.
 Students are expected not to copy any laboratory reports from classmates and copping is not
tolerated. If you are found copping from each other, zero will be assigned to that lab report.
 Students are expected to be honest and honorable in quiz and exam-taking situations.
Cheating is not tolerated. If you are found cheating, a zero will be assigned to the quiz and
exam for all involved.

6. Summary of Teaching Learning Methods:

Lecture will be used for every topic and tutorial classes will be arranged with students.
Additionally, reading assignments will be delivered in some selected topics and practical section
will be delivered side by side with theoretical section. Group discussion may be used along with
presentations on selected topics to promote cooperative learning.

7. Summary of Assessment Methods:

The learning outcomes for the course will be assessed on the basis of quiz, presentation ( written
and oral) of group works, assignments, laboratory attendance, laboratory reports and final exams.
A total of two assignments will be delivered which accounts 10% of the total mark. Homework
will be delivered at the end of each weak. The homework is not graded however; quiz will be
given based on the homework. One quiz will be delivered which accounts for 10% of the total
mark. Group presentations will be used to cover some of the contents presented in the course out
line. Topics for the group presentations will be chosen and approved by the instructor. The group
presentation will worth 10% of the total marks. Laboratory attendance will account for 10% of
the total mark and the laboratory report covers 20% of the total mark. There will not be mid term
exam but the final exam covering materials from lecture, homework and reading assignments
will worth 40% of the total marks.

8. Assignments:

Reading assignments will be delivered on topics selected by the instructor. But the reading
assignment will not be graded. Homework from the textbook and additional problem sets will be
distributed at the end of every week. The homework is not graded but it is very important, since
the quiz and final exams may include materials from homework problems so you are highly
encouraged to work hard all homework. Written assignments to be delivered may include topics

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from lectures, reading assignments, text book and reference materials. Every written assignment
will be evaluated out of 5% of the total mark.

9. Student Workload:

This course has 5 ECTS. Thus the student is expected to spend 5*25 = 125 hours on the course.

Student Workload Credit point Hours

Lecture 1.2 30
Reading assignment ( homework) 0.6 15

Experimental activity 0.72 18

Report writing 0.48 12

Group discussion and 0.12 3

presentation

Independent Learning Time 1.62 40 ½

Assessment 0.26 6½

Total 5 ECTS 125 hours

10. Policies:
11. Schedule:
Raw mark Interval of Corresponding Corresponding
Interval (100%) number grade fixed number letter grade
grades
[95,100] 4 4.0 A+

[90,95) 3.5X<4.0 3.7 A

[85,90) 3.0X<3.5 3.3. A-

[83,85) 2.7X<3.0 3.0 B+

[78,83) 2.3.0X<2.7 2.7 B

[73,78) 2.0X<2.3 2.3 C+

[65,73) 1.7X<2.0 2.0 C

[55,65) 1.3X<1.7 1.7 D

[50,55) 1.0X<1.3 1.3 E

[30,50) 1.0 1.0 FX

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[0,30) 1.0 1.0 F
Main topics to be covered;
1 Introduction
1.1. Importance of organic chemistry
1.2. Source of organic compounds
2. Functional groups occurring in Natural compounds
2.1. Nomenclature
 Hydrocarbons
 Aromatics
 Alcohols
 Carbonyl compounds
 Amines
 Carboxylic acids and Esters
2.2. Common reactions
 Hydrocarbons
 Aromatics
 Carbonyl compounds
 Amines
 Carboxylic acids and Esters
3. Stereochemistry
4. Aromatic compounds with biological importance
5. Chemistry of naturally occurring (Bio-) -organic compounds
5.1. Carbohydrates
 Nomenclature
 Structure
 Function
 Physiochemical properties
5.2. Proteins and amino acids
 Nomenclature
 Structure
 Function
 Physiochemical properties

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5.3. Fats and oils
 Nomenclature
 Structure
 Function
 Physiochemical properties
5.4. Nucleic acid
 Nomenclature
 Structure
 Function
 Physiochemical properties
6. Methods of separation and identification of bio-molecules

Practical Sections
Experiment1. Recrystallization
Experiment2. Simple distillation
Experiment3.Preparation of Aspirin
Experiment4. Preparation of soap
Experiment5. Chromatographic Separation
Experiment6. Chemical investigation of proteins and carbohydrates

Number of ECTS credits: 5 ECTS (average student working time: 5*25=125 hours)
weeks Educational activity Text book References
1 Lecture 1. Importance of organic Francis A. Carey, 2000 J. Mc Murry, 2001
Solomons, 5th
chemistry, Source of organic
edition,
compounds
Reading assignment (Homework)
Independent Learning Time

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2 Lecture 2. Functional groups J. Mc Murry, Organic Solomons G. T. W,
Organic Chemistry,
occurring in Natural compounds; Chemistry, 5th edition, 5th edition
Nomenclature (Hydrocarbons, 2001, pp (74-94, 656-686, Francis A. Carey,
Aromatics, Alcohols, Carbonyl 709-724, 743-751, 754-790, Organic Chemistry,
compounds, Amines, Carboxylic 815-829, 844-877, 977- 4th edition, 2000
acids and Esters 1006)
Reading assignment (Homework)
Independent Learning Time

3 Lecture 3. Common reactions of J. Mc Murry, Organic F. M. Manger, 2nd

hydrocarbons and aromatics Chemistry, 5th edition, Ed., 1975
2001, pp (234-253,277-288,
593-626)
Experiment1. Recrystallization
Report writing
Independent Learning Time

4 Lecture 4. Common reactions of J. Mc Murry, Organic F. M. Manger, 2nd

Carbonyl compounds, Amines, Chemistry, 5th edition, Ed., 1975
Carboxylic acids and Esters 2001, pp (764-790, 818-
829)
Assignment 1.
Independent Learning Time

5 Lecture 5. Stereochemistry J. Mc Murry, Organic F. M. Manger, 2nd

Chemistry, 5th edition, Ed., 1975
2001, pp (307-335)
Experiment2. Simple distillation
Report writing
Independent Learning Time
6 Lecture 6. Stereochemistry … J. Mc Murry, Organic F. M. Manger, 2nd
Cont’d Chemistry, 5th edition, Ed., 1975
2001, pp (307-335)
Experiment3.Preparation of
Aspirin
Report writing
Reading assignment (Homework)

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 Independent Learning Time

7 Lecture 7 Aromatic compounds F. M. Manger, 2nd

with biological importance Ed., 1975

Quiz
Assignment 2.
Independent Learning Time

8 Lecture 8. Carbohydrates; J. Mc Murry, Organic F. M. Manger, 2nd

Nomenclature and Structure Chemistry, 5th edition, Ed., 1975
2001, pp (1031-1060)
Experiment4. Preparation of soap
Report writing
Independent Learning Time

9 Lecture 9. Carbohydrates; J. Mc Murry, Organic F. M. Manger, 2nd

Function and Physiochemical Chemistry, 5th edition, Ed., 1975
properties 2001, pp (1031-1060)
Reading assignment (Homework)
Group discussion and presentation
Independent Learning Time

10 Lecture 10. Proteins and amino J. Mc Murry, Organic F. M. Manger, 2nd

acids; Nomenclature and Structure Chemistry, 5th edition, Ed., 1975
2001, pp (1074-1101)
Reading assignment (Homework)

Independent Learning Time

11 Lecture 11. Proteins and amino J. Mc Murry, Organic F. M. Manger, 2nd

acids; Function and Physiochemical Chemistry, 5th edition, Ed., 1975
properties 2001, pp (1074-1101)
Experiment5. Chromatographic
Separation
Report writing
Independent Learning Time

12 Lecture 12. Fats and oils J. Mc Murry, Organic F. M. Manger, 2nd

(Nomenclature, Structure, Chemistry, 5th edition, Ed., 1975
Function and Physiochemical 2001, pp (1119-1137)

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 properties)
Reading assignment (Homework)
Independent Learning Time
13 Lecture 13. Nucleic acid J. Mc Murry, Organic
(Nomenclature, Structure, Chemistry, 5th edition,
Function and Physiochemical 2001, pp (1151-1183)
properties)
Experiment6. Chemical
investigation of proteins and
carbohydrates
Report writing
Independent Learning Time

14 Lecture 14. Methods of separation Stryer, Biochemistry, 5th

and identification of bio- edition
molecules
Reading assignment (Homework)
Independent Learning Time

15 Lecture 15. Methods of separation Stryer, Biochemistry, 5th

and identification of bio- edition
molecules …Cont’d.
Independent Learning Time

16 Final examination period

12. Assessment Arrangements:

The assessment methods used in this course along with their weight distribution is shown below.

Assessment type No. of replicate Load per each Total load per each
replicate assessment type

Quiz 1 10% 10%

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 Assignment 2 5% 10%
Group discussion 1 10% 10%
and presentation
Lab attendance 6 10%
Lab. report 6 20%
Final exam 1 40% 40%

Total 100%

13. Module and course evaluation:

Module and course will be evaluated based on analysis of assessment results.

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