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MLS 064: Biochemistry

Module #10 Student Activity Sheet

Name: _________________________________________________________________ Class number: _______


Section: ____________ Schedule: ________________________________________ Date: ________________

Lesson title: Lipid Structure Materials:


Book, Pen and Notebook
Learning Targets:
At the end of the module, students will be able to: References:
1. Define Lipids Ubalde, Biochemistry for Allied Health
2. Identify and classify the different structures of lipids Sciences: Edric Publishing, 2019
Smith,J.G.2013.General, Organic and
Biological Chemistry, Second Edition.New
York, New York: The McGraw-Hill
companies

A. LESSON PREVIEW/REVIEW

To check the students understanding on the previous topic, the students will answer the questions below.
1. Make a flow chart of Oxidative Phosphorylation

B. MAIN LESSON

I. Definition:
 Lipids are biomolecules that are soluble in organic solvents and insoluble in water.
 They are not defined by a particular functional group, thus they have a variety of structures and
functions.
 They contain many nonpolar C—C and C—H bonds and few polar bonds resulting in their water
insolubility.

II. Importance of Lipids


 As a source of Energy -1 gram of fat when oxidized is 6kcal while similar amounts of carbohydrate can
only yield 4kcal
 Essential component of cellular structure especially cell membranes
III. Three General Characteristics of Lipids
1. They are insoluble in water but soluble in more solvents with low polarity
2. They are esters of fatty acids

This document is the property of PHINMA EDUCATION


MLS 064: Biochemistry
Module #10 Student Activity Sheet

Name: _________________________________________________________________ Class number: _______


Section: ____________ Schedule: ________________________________________ Date: ________________

3. They are utilizable by living organisms


IV. Biological Importance of Lipids
 Fats provide major way of storing chemical energy and carbon atoms in the body
 Surround and insulate vital organs
 Provide protection from mechanical shock
 Prevent the excessive loss of heat energy

V. Classification of Lipids
A. Simple Lipids – they are esters of fatty acids with various alcohols
i. Triacylglycerols
ii. Waxes
B. Compounds (complex) Lipids
i. Phospholipids
ii. Glucolipids
iii. Lipoproteins
C. Precursor and derived lipids
VI. Fatty Acids
Two types of Fatty acids
 Saturated fatty acids have no double bonds in their hydrocarbon chains
 Unsaturated fatty acids have one or more double bonds in their long hydrocarbon chains.
Generally, double bonds in naturally occurring fatty acids are cis

This document is the property of PHINMA EDUCATION


MLS 064: Biochemistry
Module #10 Student Activity Sheet

Name: _________________________________________________________________ Class number: _______


Section: ____________ Schedule: ________________________________________ Date: ________________

VII. Waxes
 Waxes are the simplest hydrolysable lipids, esters (RCOOR’) formed from a fatty acid (RCOOH) and a
high molecular weight alcohol (R’OH)
 Very hydrophobic due to long non polar carbon chains

VIII. Triacylglycerols
 Triacylglycerols or triglycerides are triesters formed from glycerol and three molecules of fatty acids
 Animal fats and vegetable oils, the most abundant lipids, are composed of TAG
 Fats – have higer melting points – they are solids at room temperature
 Oils- have lower melting points- they are liquids at room temperature
 Fats are derived from Fatty Acids having few double bonds
 Oils are derived from Fatty Acids having a larger number of double bonds

This document is the property of PHINMA EDUCATION


MLS 064: Biochemistry
Module #10 Student Activity Sheet

Name: _________________________________________________________________ Class number: _______


Section: ____________ Schedule: ________________________________________ Date: ________________

CHECK FOR UNDERSTANDING


You will answer and rationalize this by yourself. This will be recorded as your quiz. One (1) point will be given to
correct answer and another one (1) point for the correct ratio. Superimpositions or erasures in you answer/ratio
is not allowed. You are given 25 minutes for this activity:

Multiple Choice:

1. Why are linolenic and linoleic acid considered as essential fatty acids?
a. Because they are classified as omega- 3 and omega-6
b. Because they are made up of three-dimensional model for stearic which is considered as the most
common unsaturated fatty acid
c. because humans cannot synthesize them and must be acquired in diets
d. all of the above

2. Identify the Fatty Acid CH3(CH2)14COOH


a. Lauric Acid
b. Myristic Acid
c. Palmitic Acid
d. Stearic acid

3. Which of the following fatty acids contain atleast one double bonds?
a. Arachidic acid

This document is the property of PHINMA EDUCATION


MLS 064: Biochemistry
Module #10 Student Activity Sheet

Name: _________________________________________________________________ Class number: _______


Section: ____________ Schedule: ________________________________________ Date: ________________

b. Oleic acid
c. Lauric Acid
d. both and b

4. Which of the following fatty acids have the lowest melting point?
a. CH3(CH2)5CH=CH(CH2)7COOH
b. CH3(CH2)7CH=CH(CH2)7COOH
c. CH3(CH2)4CH=CHCH2CH=CH(CH2)7COOH
d. CH3(CH2)4CH=CHCH2CH= CHCH2CH =CH(CH2)7COOH

5. Which of the following has the highest melting point?


a. CH3(CH2)14COOH
b. CH3(CH2)16COOH
c. CH3(CH2)12COOH
d. CH3(CH2)10COOH

6. These are esters formed from a FA and a high molecular weight alcohol
a. Waxes
b. TAG
c. Phospholipids
d. Sphingomyelin

7. Which of the following is true about hydrolysis of Waxes?


a. Waxes when hydrolyzed with water in the presence of acid or base re-form the RCOOH and R’OH
b. Waxes when hydrolyzed with water in the presence of acid or base converts to RCOOH and R’OH
c. Waxes when hydrolyzed with water in the presence of acid or base re-form the alkane
d. Waxes when hydrolyzed with water in the presence of acid or base re-form the Fatty acids

8. These are triesters formed from glycerol and three molecules of Fatty acids
a. Sphingomyelin
b. Triglycerides
c. Phospholipids
d. Glycerol

9. Which of the following is not true about TAG


a. Fats and oils are glycerol with same physical properties
b. Fats have lower melting point while Oils have higher melting point
c. Fats are derived from FA having few double bonds
d. Oils are derived from FA having few double bonds

10. Which of the following is true about saturated Fatty Acids


a. They are usually liquid in room temperature
b. They are found rich in plant oils, nuts, soybeans
c. They are are found to be one cause of hypercholesterolemia
d. One trans double bond in the carbon chains

This document is the property of PHINMA EDUCATION


MLS 064: Biochemistry
Module #10 Student Activity Sheet

Name: _________________________________________________________________ Class number: _______


Section: ____________ Schedule: ________________________________________ Date: ________________

RATIONALIZATION ACTIVITY (DURING THE FACE TO FACE INTERACTION WITH THE STUDENTS)
The instructor will now rationalize the answers to the students and will encourage them to ask questions and to
discuss among their classmates for 20 minutes.

1. ANSWER: ________
RATIO:_______________________________________________________________________________
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2. ANSWER: ________
RATIO:_______________________________________________________________________________
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3. ANSWER: ________
RATIO:_______________________________________________________________________________
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4. ANSWER: ________
RATIO:_______________________________________________________________________________
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5. ANSWER: ________
RATIO:_______________________________________________________________________________
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6. ANSWER: ________
RATIO:_______________________________________________________________________________
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7. ANSWER: ________

This document is the property of PHINMA EDUCATION


MLS 064: Biochemistry
Module #10 Student Activity Sheet

Name: _________________________________________________________________ Class number: _______


Section: ____________ Schedule: ________________________________________ Date: ________________

RATIO:_______________________________________________________________________________
_____________________________________________________________________________________
_____________________________________________________________________________________

8. ANSWER: ________
RATIO:_______________________________________________________________________________
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9. ANSWER: ________
RATIO:_______________________________________________________________________________
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10. ANSWER: ________


RATIO:_______________________________________________________________________________
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C. LESSON WRAP-UP

You will now mark (encircle) the session you have finished today in the tracker below. This is simply a visual to
help you track how much work you have accomplished and how much work there is left to do.

You are done with the session! Let’s track your progress.

MUDDIEST POINT - “In today’s session, what was the least clear to you?”
1. _____________________________________________________________________
2. _____________________________________________________________________

This document is the property of PHINMA EDUCATION

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