Revision date: 20/09/2018 Revision: 3 Supersedes date: 17/03/2016

SAFETY DATA SHEET

ELISA COATING BUFFER

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1. Product identifier

Product name ELISA COATING BUFFER

1.2. Relevant identified uses of the substance or mixture and uses advised against
Identified uses For research use only.

1.3. Details of the supplier of the safety data sheet

Supplier Web: www.bio-rad-antibodies.com
Bio-Rad
Endeavour House
Langford Business Park
Kidlington
Oxford
OX5 1GE
Tel. +44 (0)1865 852700
[email protected]

Contact person Technical Services Manager

1.4. Emergency telephone number

Emergency telephone +1 7037415970 (CHEMTREC)

SECTION 2: Hazards identification

2.1. Classification of the substance or mixture

Classification (EC 1272/2008)
Physical hazards Not Classified

Health hazards Acute Tox. 4 - H302

Environmental hazards Aquatic Chronic 3 - H412

Human health This product is harmful if swallowed.

Environmental The product contains a substance which is harmful to aquatic organisms and which may
cause long-term adverse effects in the aquatic environment.

2.2. Label elements

Pictogram

Signal word Warning

Hazard statements H302 Harmful if swallowed.

H412 Harmful to aquatic life with long lasting effects.

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Precautionary statements P273 Avoid release to the environment.

P301+P312 IF SWALLOWED: Call a POISON CENTRE/doctor if you feel unwell.
P264 Wash hands/skin thoroughly after handling.
P501 Dispose of contents/containers in accordance with local regulations

Contains SODIUM AZIDE

Supplementary precautionary P270 Do not eat, drink or smoke when using this product.
statements P330 Rinse mouth.

2.3. Other hazards

No information available.

SECTION 3: Composition/information on ingredients

3.2. Mixtures

SODIUM AZIDE 0.5%

CAS number: 26628-22-8 EC number: 247-852-1
M factor (Acute) = 1 M factor (Chronic) = 1

Classification Classification (67/548/EEC or 1999/45/EC)

Acute Tox. 2 - H300 T+;R28 R32 N;R50/53
Aquatic Acute 1 - H400
Aquatic Chronic 1 - H410

The Full Text for all R-Phrases and Hazard Statements are Displayed in Section 16.

SECTION 4: First aid measures

4.1. Description of first aid measures

Inhalation If spray/mist has been inhaled, proceed as follows. Move affected person to fresh air and
keep warm and at rest in a position comfortable for breathing. Get medical attention if any
discomfort continues.

Ingestion Never give anything by mouth to an unconscious person. Do not induce vomiting. Rinse
mouth thoroughly with water. Get medical attention.

Skin contact Remove contaminated clothing and rinse skin thoroughly with water. Get medical attention
promptly if symptoms occur after washing.

Eye contact Remove any contact lenses and open eyelids wide apart. Continue to rinse for at least 15
minutes. Continue to rinse for at least 15 minutes. Get medical attention. Show this Safety
Data Sheet to the medical personnel.

4.2. Most important symptoms and effects, both acute and delayed
Inhalation May cause cause coughing or mild irritation.

Ingestion May cause discomfort if swallowed.

Skin contact Prolonged skin contact may cause redness and irritation.

Eye contact May cause temporary eye irritation.

4.3. Indication of any immediate medical attention and special treatment needed
Notes for the doctor No specific recommendations.

SECTION 5: Firefighting measures

5.1. Extinguishing media

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Suitable extinguishing media The product is not flammable. Use fire-extinguishing media suitable for the surrounding fire.

5.2. Special hazards arising from the substance or mixture

Specific hazards 7.2

Hazardous combustion Does not decompose when used and stored as recommended.
products

5.3. Advice for firefighters

Protective actions during No specific firefighting precautions known.
firefighting

Special protective equipment Use protective equipment appropriate for surrounding materials.
for firefighters

SECTION 6: Accidental release measures

6.1. Personal precautions, protective equipment and emergency procedures

Personal precautions Wear suitable protective equipment, including gloves, goggles/face shield, respirator, boots,
clothing or apron, as appropriate.

6.2. Environmental precautions

Environmental precautions Avoid the spillage or runoff entering drains, sewers or watercourses.

6.3. Methods and material for containment and cleaning up

Methods for cleaning up Absorb spillage with non-combustible, absorbent material. Flush contaminated area with
plenty of water. Avoid the spillage or runoff entering drains, sewers or watercourses.

6.4. Reference to other sections

Reference to other sections Wear protective clothing as described in Section 8 of this safety data sheet.

SECTION 7: Handling and storage

7.1. Precautions for safe handling

Usage precautions Avoid spilling. Avoid contact with skin and eyes. Good personal hygiene procedures should be
implemented. Wash hands and any other contaminated areas of the body with soap and
water before leaving the work site.

7.2. Conditions for safe storage, including any incompatibilities

Storage precautions Keep only in the original container. Store at specified temperature. Refer to product label.

7.3. Specific end use(s)

Specific end use(s) The identified uses for this product are detailed in Section 1.2.

SECTION 8: Exposure Controls/personal protection

8.1. Control parameters

Occupational exposure limits
SODIUM AZIDE
Long-term exposure limit (8-hour TWA): WEL 0.1 mg/m³
Short-term exposure limit (15-minute): WEL 0.3 mg/m³
as NaN3
Sk
WEL = Workplace Exposure Limit
Sk = Can be absorbed through the skin.

8.2. Exposure controls

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Protective equipment

Appropriate engineering Provide adequate ventilation. Avoid inhalation of vapours and spray/mists. Observe any
controls occupational exposure limits for the product or ingredients.

Eye/face protection Eyewear complying with an approved standard should be worn if a risk assessment indicates
eye contact is possible. The following protection should be worn: Chemical splash goggles or
face shield.

Hand protection Chemical-resistant, impervious gloves complying with an approved standard should be worn if
a risk assessment indicates skin contact is possible.

Other skin and body Wear appropriate clothing to prevent any possibility of skin contact. Wear apron or protective
protection clothing in case of contact.

Hygiene measures Wash promptly if skin becomes contaminated. Promptly remove any clothing that becomes
contaminated. Use appropriate skin cream to prevent drying of skin. When using do not eat,
drink or smoke.

Respiratory protection No specific recommendations. Respiratory protection must be used if the airborne
contamination exceeds the recommended occupational exposure limit.

SECTION 9: Physical and Chemical Properties

9.1. Information on basic physical and chemical properties

Appearance Liquid.

Colour Clear liquid.

Odour No characteristic odour.

pH pH (concentrated solution): 8.2 - 8.6

Melting point Not determined.

Initial boiling point and range <100 @°C @ 760 mm Hg

Flash point Not applicable.

Evaporation rate Not determined.

Upper/lower flammability or Not applicable.

explosive limits

Vapour pressure Not determined.

Vapour density Not determined.

Relative density Not determined.

Solubility(ies) Soluble in water.

Partition coefficient Not determined.

Auto-ignition temperature Not determined.

Decomposition Temperature Not determined.

Viscosity Not determined.

Explosive properties Not determined.

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Oxidising properties Not determined.

9.2. Other information

Other information None.

SECTION 10: Stability and reactivity

10.1. Reactivity
Reactivity No data available.

10.2. Chemical stability

Stability Stable at normal ambient temperatures.

10.3. Possibility of hazardous reactions

Possibility of hazardous Will not polymerise.
reactions

10.4. Conditions to avoid

Conditions to avoid Avoid exposure to high temperatures or direct sunlight.

10.5. Incompatible materials

Materials to avoid Hydrocarbons - halogenated. Strong acids. Metals

10.6. Hazardous decomposition products

Hazardous decomposition Does not decompose when used and stored as recommended.
products

SECTION 11: Toxicological information

11.1. Information on toxicological effects

Toxicological effects No information available.

Other health effects IARC Not Listed.

Acute toxicity - oral

Notes (oral LD₅₀) Not determined.

ATE oral (mg/kg) 1,000.0

Skin corrosion/irritation
Human skin model test Not determined.

Extreme pH 7.2

Serious eye damage/irritation

Serious eye damage/irritation Not determined.

Germ cell mutagenicity

Genotoxicity - in vitro Not determined.

Carcinogenicity
Carcinogenicity Not determined.

Reproductive toxicity
Reproductive toxicity - fertility Not determined.

Specific target organ toxicity - single exposure

STOT - single exposure Not determined.

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Specific target organ toxicity - repeated exposure

STOT - repeated exposure Not determined.

Aspiration hazard
Aspiration hazard Not determined.

General information Knowledge about health hazard is incomplete.

Inhalation Gas or vapour in high concentrations may irritate the respiratory system. Symptoms following
overexposure may include the following: Coughing.

Ingestion May cause discomfort if swallowed.

Skin contact Liquid may irritate skin.

Eye contact Vapour or spray in the eyes may cause irritation and smarting.

Acute and chronic health Because of the product's quantity and composition, the health hazard is regarded as low.
hazards

Route of exposure Ingestion. Skin and/or eye contact

Toxicological information on ingredients.

SODIUM AZIDE

Acute toxicity - oral

ATE oral (mg/kg) 5.0

SECTION 12: Ecological Information

Ecotoxicity There are no data on the ecotoxicity of this product.

12.1. Toxicity
Acute aquatic toxicity
Acute toxicity - fish Not determined.

Acute toxicity - aquatic EC₅₀, 48 hours: Daphnia pulex (Water flea) - 4.2 mg/l mg/l, Daphnia magna
invertebrates

Ecological information on ingredients.

SODIUM AZIDE

Acute aquatic toxicity

LE(C)₅₀ 0.1 < L(E)C50 ≤ 1

M factor (Acute) 1

Chronic aquatic toxicity

M factor (Chronic) 1

12.2. Persistence and degradability

Persistence and degradability There are no data on the degradability of this product.

12.3. Bioaccumulative potential

Bioaccumulative potential No data available on bioaccumulation.

Partition coefficient Not determined.

12.4. Mobility in soil

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Mobility The product is soluble in water.

12.5. Results of PBT and vPvB assessment

Results of PBT and vPvB No information available
assessment

12.6. Other adverse effects

Other adverse effects Not determined.

SECTION 13: Disposal considerations

13.1. Waste treatment methods

General information Waste is classified as hazardous waste. Dispose of waste to licensed waste disposal site in
accordance with the requirements of the local Waste Disposal Authority.

Disposal methods Dispose of waste to licensed waste disposal site in accordance with the requirements of the
local Waste Disposal Authority.

SECTION 14: Transport information

General The product is not covered by international regulations on the transport of dangerous goods
(IMDG, IATA, ADR/RID).

Road transport notes Not classified.

Rail transport notes Not classified.

Sea transport notes Not classified.

Air transport notes Not classified.

14.1. UN number
Not applicable.

14.2. UN proper shipping name

Not applicable.

14.3. Transport hazard class(es)

Not applicable.

14.4. Packing group

Not applicable.

14.5. Environmental hazards

Environmentally hazardous substance/marine pollutant

No.

14.6. Special precautions for user

Not applicable.

14.7. Transport in bulk according to Annex II of MARPOL and the IBC Code
Transport in bulk according to Not applicable.
Annex II of MARPOL 73/78
and the IBC Code

SECTION 15: Regulatory information

15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture

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EU legislation Regulation (EC) No 1907/2006 of the European Parliament and of the Council of 18
December 2006 concerning the Registration, Evaluation, Authorisation and Restriction of
Chemicals (REACH) (as amended).

Guidance Workplace Exposure Limits EH40.

Approved Classification and Labelling Guide (Sixth edition) L131.
Safety Data Sheets for Substances and Preparations.

15.2. Chemical safety assessment

No chemical safety assessment has been carried out.

SECTION 16: Other information

General information Only trained personnel should use this material.

Revision date 20/09/2018

Revision 3

Supersedes date 17/03/2016

SDS number 10383

Risk phrases in full R22 Harmful if swallowed.

R28 Very toxic if swallowed.
R32 Contact with acids liberates very toxic gas.
R50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic
environment.
R52/53 Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic
environment.

Hazard statements in full H300 Fatal if swallowed.

H302 Harmful if swallowed.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.
H412 Harmful to aquatic life with long lasting effects.

This information relates only to the specific material designated and may not be valid for such material used in combination
with any other materials or in any process. Such information is, to the best of the company's knowledge and belief, accurate
and reliable as of the date indicated. However, no warranty, guarantee or representation is made to its accuracy, reliability or
completeness. It is the user's responsibility to satisfy himself as to the suitability of such information for his own particular use.

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