호모사피엔스 종의 단백질 코딩 유전자
ATP 바인딩 카세트 서브 패밀리 C 멤버 4 (ABCC4)는 다의약품 저항 관련 단백질 4(MRP4 ) 또는 다중 의 특정 유기 음이온 전달체 B (MOAT-B)로도 알려져 있으며, ABCC4 유전자 에 의해 인코딩되는 단백질 이다.[5] [6]
ABCC4는 세포내 순환 핵물질 수준의 조절기 및 핵으로의 cAMP 의존적 신호 전달의 중재자 역할을 한다.[7] 또한 MRP4/ABCC4는 수용체를 결합할 수 있는 세포 밖으로 프로스타글란딘(예: PGE2)을 운반한다.[8]
MRP4/ABCC4 표현은 여러 암에서 조절이 잘 되지 않으며 복막 내막증에서도 조절이 잘 된다.[12]
대화형 경로 지도 각 기사에 연결하려면 아래의 유전자, 단백질, 대사물을 클릭하십시오. [§ 1]
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