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SAFETY DATA SHEET

LIPOTEC SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006
Date: April 2012 Revision: 8

SECTION 1: IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE

COMPANY/UNDERTAKING
1.1 PRODUCT IDENTIFIER ARGIRELINE® NP
CODE 05C037
1.2 RELEVANT IDENTIFIED USES OF THE This mixture is intended to be used
SUBSTANCE OR MIXTURE AND USES exclusively as a COSMETIC INGREDIENT
ADVISED AGAINST
1.3 DETAILS OF THE SUPPLIER OF THE LIPOTEC S.A.
SAFETY DATA SHEET Polígon Industrial Camí Ral
C/Isaac Peral 17
08850 Gavà (Barcelona)
SPAIN
Phone. +34 93 638 80 00
Fax. +34 93 638 93 93
E-mail: [email protected]
1.4 EMERGENCY TELEPHONE NUMBER 704.10.00.87 (Spain)

SECTION 2: HAZARDS IDENTIFICATION

2.1 CLASSIFICATION OF THE SUBSTANCE OR Not classified as hazardous
MIXTURE
According to Regulation (EC) No 1272/2008
According to Directive 1999/45/EC
2.2 LABEL ELEMENTS None
2.3 OTHER HAZARDS None known if handled in accordance with
good industrial hygiene and safety practice

SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS

3.1 SUBSTANCES -
3.2 MIXTURES ARGIRELINE® NP is a solution containing active
ingredients
INCI Name WATER (AQUA), ACETYL HEXAPEPTIDE-8, POTASSIUM
SORBATE, PHENOXYETHANOL.

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INCI name CAS EINECS Classification Concentration

Water (Aqua) 7732-18-5 231-791-2 Not classified -
Acetyl 616204-22-9 - Not classified -
Hexapeptide-8
Potassium Sorbate 24634-61-5 246-376-1 Not classified -
Phenoxyethanol 122-99-6 204-589-7 Acute Tox. 4 0.45 - 0.55%
Eye Irrit. 2

SECTION 4: FIRST AID MEASURES

4.1 DESCRIPTION OF FIRST AID MEASURES
General advice Remove contaminated clothing and wash
with water
Skin contact Rinse with water
Eye contact Rinse immediately with plenty of water
Ingestion Not toxic. If discomfort symptoms appear,
call a physician
Inhalation Not applicable
4.2 MOST IMPORTANT SYMPTOMS AND None expected
EFFECTS, BOTH ACUTE AND DELAYED
4.3 INDICATION OF ANY IMMEDIATE None known
MEDICAL ATTENTION AND SPECIAL
TREATMENT NEEDED
+

SECTION 5: FIREFIGHTING MEASURES

5.1 EXTINGUISHING MEDIA Water, carbon dioxide, foam, dry powder
5.2 SPECIAL HAZARDS ARISING FROM THE Unknown
SUBSTANCE OR MIXTURE
5.3 ADVICE FOR FIREFIGHTERS No special requirements needed

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SECTION 6: ACCIDENTAL RELEASE MEASURES

6.1 PERSONAL PRECAUTIONS, PROTECTIVE Avoid direct eye contact
EQUIPMENT AND EMERGENCY
PROCEDURES
6.2 ENVIRONMENTAL PRECAUTIONS None known
6.3 METHODS AND MATERIAL FOR A spill can be contained by capping the
CONTAINMENT AND CLEANING UP container
For cleaning up a spill use a suitable
absorbent and pump it into the correct
container
6.4 REFERENCE TO OTHER SECTIONS See section 8

SECTION 7: HANDLING AND STORAGE

7.1 PRECAUTIONS FOR SAFE HANDLING Handle in accordance with good industrial
hygiene and safety practice
Avoid spills
Do not eat, drink and smoke in work areas
7.2 CONDITIONS FOR SAFE STORAGE, Keep the product in a clean, cool and dark
INCLUDING ANY INCOMPATIBILITIES place
Avoid extreme environmental conditions
7.3 SPECIFIC END USE(S) See subsection 1.2

SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION

8.1 CONTROL PARAMETERS Handle in accordance with good industrial
hygiene and safety practice
8.2 EXPOSURE CONTROLS
APPROPRIATE ENGINEERING CONTROLS -
INDIVIDUAL PROTECTION MEASURES
Eye/Face protection Safety glasses
Skin protection Gloves
No additional skin protection measures
needed
Respiratory protection No protection required
Thermal hazards -
ENVIRONMENTAL EXPOSURE CONTROLS Environmental protection legislation for
every country must be observed

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SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES

9.1 INFORMATION ON BASIC PHYSICAL AND
CHEMICAL PROPERTIES
Appearance Transparent solution
Colour Colourless
Odour Characteristic
pH 3.0 – 6.0
Melting point -
Freezing point -
Initial boiling point -
Boiling range -
Flash point -
Evaporation rate -
Flammability -
Upper/lower flammability limits -
Upper/lower explosive limits -
Vapour pressure -
Vapour density -
Relative density 0.94 – 1.04 g/mL
Solubility -
Partition coefficient n-octanol/water -
Auto-ignition temperature -
Decomposition temperature -
Viscosity -
Explosive properties -
Oxidising properties -
9.2 OTHER INFORMATION -

SECTION 10: STABILITY AND REACTIVITY

10.1 REACTIVITY No reactivity hazards known
10.2 CHEMICAL STABILITY The substance/mixture is stable if stored and
handled as recommended
10.3 POSSIBILITY OF HAZARDOUS No hazardous reactions known if stored and
REACTIONS handled as recommended
10.4 CONDITIONS TO AVOID None known if stored and handled as
recommended
10.5 INCOMPATIBLE MATERIALS None known
10.6 HAZARDOUS DECOMPOSITION No hazardous decomposition products
PRODUCTS known if stored and handled as
recommended

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SECTION 11: TOXICOLOGICAL INFORMATION

11.1 INFORMATION ON TOXICOLOGICAL
EFFECTS
Acute toxicity Acetyl Hexapeptide-8 is not considered toxic
after oral ingestion
Skin irritation Not considered irritant
Eye irritation Not considered irritant
Corrosivity -
Sensitisation Not considered sensitising
Repeated dose toxicity -
Carcinogenicity -
Mutagenicity Acetyl Hexapeptide-8 is not considered
mutagenic.
Toxicity for reproduction -
Other information Standard and well-defined safety tests have
been performed with the active ingredients
involved, which have proven to be safe for
cosmetic use.
INFORMATION ON LIKELY ROUTES OF No health effects known for the
EXPOSURE substance/mixture
SYMPTOMS RELATED TO THE PHYSICAL, No potential adverse health effects or
CHEMICAL AND TOXICOLOGICAL symptoms known
CHARACTERISTICS
DELAYED AND IMMEDIATE EFFECTS AS No effects known
WELL AS CHRONIC EFFECTS FROM SHORT
AND LONG-TERM EFFECTS
INTERACTIVE EFFECTS No effects known
ABSENCE OF SPECIFIC DATA -
MIXTURE VERSUS SUBSTANCE INFORMATION No information available
OTHER INFORMATION -

SECTION 12: ECOLOGICAL INFORMATION

12.1 TOXICITY Not determined
12.2 PERSISTENCE AND DEGRADABILITY Not determined
12.3 BIOACCUMULATIVE POTENTIAL Based on product properties, no
bioaccumulation is expected. The product has
not been tested
12.4 MOBILITY IN SOIL Not determined
12.5 RESULTS OF PBT AND vPvB ASSESSMENT Not determined
12.6 OTHER ADVERSE EFFECTS None known

SECTION 13: DISPOSAL CONSIDERATIONS

13.1 WASTE TREATMENT METHODS This material and its container should be
disposed safely avoiding release to the
environment
National and regional provisions that may be
in force should be observed

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SECTION 14: TRANSPORT INFORMATION

14.1 UN NUMBER Not applicable
14.2 UN PROPER SHIPPING NAME Not applicable
14.3 TRANSPORT HAZARD CLASS(ES) Not applicable
14.4 PACKING GROUP Not applicable
14.5 ENVIRONMENTAL HAZARDS Not applicable
14.6 SPECIAL PRECAUTIONS FOR USER None
14.7 TRANSPORT IN BULK ACCORDING TO Not applicable
ANNEX II OF MARPOL73/78 AND THE IBC
CODE

SECTION 15: REGULATORY INFORMATION

15.1 SAFETY, HEALTH AND ENVIRONMENTAL Relevant national laws should be carefully
REGULATIONS/LEGISLATION SPECIFIC FOR observed
THE SUBSTANCE OR MIXTURE
15.2 CHEMICAL SAFETY ASSESSMENT No chemical safety assessment has been
carried out for the substance/mixture

SECTION 16: OTHER INFORMATION

Evaluation of the need of classification/no classification under Regulation (EC) No 1272/2008
has been carried out by evaluating the available information on the substance/mixture

Classification of the substance/mixture

- No classification needed
Relevant R phrases
- None
Relevant hazard statements
- None
Relevant safety phrases
- None
Relevant precautionary statements
- None
Training for workers
- No special training required

Text marked with an asterisk (*) indicates an amendment from the previous version

All the information and instructions contained in this Safety Data Sheet are based on the current state of scientific
and technical knowledge at the date indicated on the present Safety Data Sheet. Lipotec S.A. shall not be held
responsible for any defect in the product covered by this Safety Data Sheet. The information contained herein is
based on the present state of our knowledge and does not therefore guarantee certain properties. Recipients of our
product must take responsibility for observing existing laws and regulations.

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