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Pharmaceuticals

BPOC

Notar Victor, gr.26

1. Ce este BPOC?
Boala pulmonară obstructivă cronică
(BPOC) se caracterizează prin limitarea
persistentă și progresivă a fluxului de
aer, printr-un răspuns inflamator cronic
la particulele nocive sau gaze. 
Limitarea cronică a fluxului respirator
este cauzată de o combinație de mici
leziuni respiratorii (bronșiolită
obstructivă) și distrucții
parenchimatoase (emfizem), în
combinație ce variază de la bolnav la
bolnav.
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 Expunere la fum de
Polimorfism genetic
tigara si substante
TGF-b1/ deficit de a1AT
toxice volatile

Citokinele si
proteazele Apoptoza, Scaderea
determina necroza sintezei
degradarea MEC matricei
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Distrugerea parenchimului pulmonar Pharmaceuticals

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1. Ce este BPOC?

Inflamația cronică cauzează modificări

structurale și îngustarea căilor
respiratorii distale. Distrugerea
parenchimului prin procese inflamatorii
duce la pierderea simultană a alveolelor,
astfel scăzând reculul elastic al
plămânului.

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 Mecanisme
Expunerea repetata la substante toxice
fiziopatologice in
determina o inflamatie cronica la nivelul
plamanilor. patogeneza BPOC
Astfel, apare un infiltrat inflamator format din
neutrofile, macrofage si limfocite. Celulele
secreta citokine, elastaze si oxidanti,
contribuind la stresul oxidativ care distruge
MEC prin proteoliza. Produsii de degradare ai
elastinei contribuie la cronicizare.

In functie de raspunsul organismului la

agresiune, putem avea o distructie tisulara fara
fibroza ( emfizem ) sau fibroza interstitiala .
Studii recente arata ca principalul factor care
influenteaza evolutia bolii este raspunsul
celulelor mezenchimale.

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 Factori de risc in aparitia si evolutia
BPOC
Add Add Add Add Add
Picture Picture Picture Picture Picture

raspunsul Varsta
Deficit Expunere la Fumat celulelor
congenital de a-1 poluanti, mezenchimale la
antitripsina combustibili, agresiuni
subst toxice

Etiam aliquet eu mi Integer convallis Reparatia inadecvata Ut congue quis tortor

80% din acesti
pacienti dezvolta
quis lacinia. Ut suscipit ante eu a testului pulmonar in varius eget sodales. Contoso
fermentum a magna varius. Morbi a purus urma leziunilor Pharmaceuticals
emfizem pulmonar ut eleifend. dolor.
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 Prioritize Authorize Monetize Tratament BPOC
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 Unique First to Market
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Product
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ipsum varius finibus
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Investigatii clinice
pentru diagnostic
BPOC

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 Section Divider
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consectetur adipiscing elit Pharmaceuticals

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Business Model
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Research Finance Invest

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adipiscing elit. fermentum a magna varius. Morbi a purus
ut eleifend. dolor.

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Market Opportunity Option 1
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$1B $2B
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Market Opportunity Option 2
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$3B
Opportunity to Build
$2B
Freedom to Invent
$1B
Few Competitors

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amet, consectetur lacinia. Ut fermentum a ante eu varius. Morbi a
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Competition Option 1

Contoso Pharmaceuticals Competitor

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lectus. In at porta mauris.

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Competition Option 2
Convenience

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Expensive Affordable

Inconvenient Contoso
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Growth Strategy
How will we scale in the future

Phase 1 Phase 2 Phase 3

Month, Year Month, Year Month, Year

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Traction
Forecasting for success

Vendors Users Gross Company

Revenue Revenue Gross Revenue
$300,000

20YY 0 0 $0 $0
$250,000

20YY 10 100 $6,750 $1,013 $200,000

$150,000
20YY 50 500 $33,750 $5,063

$100,000
20YY 200 2000 $135,000 $20,250
$50,000

20YY 400 4000 $270,000 $40,500 $0

1 2 3 4 5 Contoso
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Timeline
Our two-year action plan

Trials Marketing Launch

Month, 20YY Month, 20YY Month, 20YY

AUG SEP OCT NOV DEC JAN FEB MAR APR MAY JUN JUL AUG SEP OCT NOV DEC JAN FEB MAR APR MAY

20YY 20YY

Legislation Investment Procurement

Month, 20YY Month, 20YY Month, 20YY

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Financials
Year 1 Year 2 Year 3
Detailers 5,000 40,000 160,000
Users 50,000 400,000 1 600,000
Sales 500,000 4 000,000 16 000,000
Average Price per Sale 75 80 90
Revenue @ 15% 5 625,000 48 000,000 216 000,000
• Cost of Revenue 0 0 0
Gross Profit 5 625,000 48 000,000 216 000,000
Expenses
• Sales & Marketing 5 062,500 38 400,000 151 200,000 70%
• Customer Service 1 687,500 9 600,000 21 600,000 10%

• Product
Development 562,500 2 400,000 10 800,000 5%
• Research 281,250 2 400,000 4 320,000 2%
Total Expenses 7 593,750 52 800,000 187 920,000
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EBIT -1 968,750 -4 800,000 28 080,000 13% Pharmaceuticals

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Team

Mirjam Nils Victoria Lindqvist Angelica Astrom

COO COB CFO

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Integer convallis suscipit ante eu hendrerit ultrices eu nec nulla.
varius.

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Team Alternate

Mirjam Victoria Alexander

Nilsson Lindqvist Martensson
COO COB CFO

Angelica Mira Flora

Astrom Karlsson Berggren
Head of Operations Head of Technical Creative Director

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Funding

Fund Category Fund Category

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consectetur adipiscing elit. $14,000 $12,000

$32,000
$82,000

Fund Category Fund Category

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• Lorem ipsum dolor sit amet, consectetur
adipiscing elit. Etiam aliquet eu mi quis
lacinia. Summary
• Ut fermentum a magna ut eleifend. Integer
convallis suscipit ante eu varius. Morbi a Summary tagline or
purus dolor. Suspendisse sit amet ipsum sub-headline
finibus justo viverra blandit.
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Thank You
April Hansson

+1 23 987 6554
[email protected]
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www.contoso.com Pharmaceuticals

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