SLC14A1 식별자 에일리어스 SLC14A1 외부 ID OMIM : 613868 MGI : 1351654 HomoloGene : 9285 GenCard : SLC14A1 맞춤법 종. 인간 마우스 엔트레즈 앙상블 유니프로트 RefSeq(mRNA) RefSeq(단백질) 장소(UCSC) Chr 18: 45.69 ~45.75 Mb Chr 18: 78.14 ~78.19 Mb PubMed 검색[3] [4] 위키데이터
요소수송체 1은 SLC14A1 [5] [6] 유전자 에 의해 인체에서 암호화되는 단백질 이다.
기능. SLC14A1은 적혈구 와 신장 에서 발현되는 요소수송체 (UTB)를 코드한다. SLC14A2 및 SLC14A1은 용질담체족 14를 구성한다.UTB 단백질은 키드 항원계 를 구성한다.
레퍼런스 ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG00000141469 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000059336 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Olives B, Mattei MG, Huet M, Neau P, Martial S, Cartron JP, Bailly P (Aug 1995). "Kidd blood group and urea transport function of human erythrocytes are carried by the same protein" . J Biol Chem . 270 (26): 15607–10. doi :10.1074/jbc.270.26.15607 PMID 7797558 . ^ "Entrez Gene: SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)" .
추가 정보 Geitvik GA, Høyheim B, Gedde-Dahl T, et al. (1987). "The Kidd (JK) blood group locus assigned to chromosome 18 by close linkage to a DNA-RFLP". Hum. Genet . 77 (3): 205–9. doi :10.1007/BF00284470 . PMID 2890568 . S2CID 23739401 . Olives B, Neau P, Bailly P, et al. (1995). "Cloning and functional expression of a urea transporter from human bone marrow cells" . J. Biol. Chem . 269 (50): 31649–52. doi :10.1016/S0021-9258(18)31744-7 PMID 7989337 . Davey S, Beach D (1996). "RACH2, a novel human gene that complements a fission yeast cell cycle checkpoint mutation" . Mol. Biol. Cell . 6 (10): 1411–21. doi :10.1091/mbc.6.10.1411 . PMC 301296 PMID 8573795 . Olivès B, Martial S, Mattei MG, et al. (1996). "Molecular characterization of a new urea transporter in the human kidney" (PDF) . FEBS Lett . 386 (2–3): 156–60. doi :10.1016/0014-5793(96)00425-5 . PMID 8647271 . S2CID 13312002 . Olivès B, Merriman M, Bailly P, et al. (1997). "The molecular basis of the Kidd blood group polymorphism and its lack of association with type 1 diabetes susceptibility" . Hum. Mol. Genet . 6 (7): 1017–20. doi :10.1093/hmg/6.7.1017 PMID 9215669 . Lucien N, Sidoux-Walter F, Olivès B, et al. (1998). "Characterization of the gene encoding the human Kidd blood group/urea transporter protein. Evidence for splice site mutations in Jknull individuals" . J. Biol. Chem . 273 (21): 12973–80. doi :10.1074/jbc.273.21.12973 PMID 9582331 . Irshaid NM, Thuresson B, Olsson ML (1998). "Genomic typing of the Kidd blood group locus by a single-tube allele-specific primer PCR technique" . Br. J. Haematol . 102 (4): 1010–4. doi :10.1046/j.1365-2141.1998.00874.x PMID 9734652 . S2CID 19082798 . Sidoux-Walter F, Lucien N, Olivès B, et al. (1999). "At physiological expression levels the Kidd blood group/urea transporter protein is not a water channel" . J. Biol. Chem . 274 (42): 30228–35. doi :10.1074/jbc.274.42.30228 PMID 10514515 . Irshaid NM, Henry SM, Olsson ML (2000). "Genomic characterization of the kidd blood group gene:different molecular basis of the Jk(a-b-) phenotype in Polynesians and Finns". Transfusion . 40 (1): 69–74. doi :10.1046/j.1537-2995.2000.40010069.x . PMID 10644814 . S2CID 43843439 . Sidoux-Walter F, Lucien N, Nissinen R, et al. (2000). "Molecular heterogeneity of the Jk(null) phenotype: expression analysis of the Jk(S291P) mutation found in Finns" . Blood . 96 (4): 1566–73. doi :10.1182/blood.V96.4.1566 PMID 10942407 . Lucien N, Chiaroni J, Cartron JP, Bailly P (2002). "Partial deletion in the JK locus causing a Jk(null) phenotype". Blood . 99 (3): 1079–81. doi :10.1182/blood.V99.3.1079 . PMID 11807016 . Irshaid NM, Eicher NI, Hustinx H, et al. (2002). "Novel alleles at the JK blood group locus explain the absence of the erythrocyte urea transporter in European families" . Br. J. Haematol . 116 (2): 445–53. doi :10.1046/j.1365-2141.2002.03238.x PMID 11841450 . S2CID 25830269 . Lucien N, Sidoux-Walter F, Roudier N, et al. (2002). "Antigenic and functional properties of the human red blood cell urea transporter hUT-B1" . J. Biol. Chem . 277 (37): 34101–8. doi :10.1074/jbc.M205073200 PMID 12093813 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Inoue H, Jackson SD, Vikulina T, et al. (2004). "Identification and characterization of a Kidd antigen/UT-B urea transporter expressed in human colon". Am. J. Physiol., Cell Physiol . 287 (1): C30–5. doi :10.1152/ajpcell.00443.2003 . PMID 14985236 .
그룹별
SLC1 ~ 10
(1): (2): (3): (4): (5): (6): (7): (8): (9): (10):
SLC11–20
(11): (12): (13): (14): (15): (16): (17): (18): (19): (20):
SLC21~30
(21): (22): (23): (24): (25): (26): (27): (28): (29): (30):
SLC31~40
(31): (32): (33): (34): (35): (36): (37): (38): (39): (40):
SLC41~48
(41): (42): (43): (44): (45): (46): (47): (48):
