LPAR5

LPAR5
LPAR5
식별자
별칭LPAR5, GPR92, GPR93, KPG_010, LPA5, 리소포인산 수용체 5
외부 IDOMIM: 606926 MGI: 2685918 호몰로진: 10696 GeneCard: LPAR5
직교체
인간마우스
엔트레스
앙상블
유니프로트
RefSeq(mRNA)

NM_020400
NM_001142961

NM_001163268
NM_001163269

RefSeq(단백질)

NP_001136433
NP_065133

NP_001156740
NP_001156741

위치(UCSC)Chr 12: 6.62 – 6.64MbChr 6: 125.04 – 125.06Mb
PubMed 검색[3][4]
위키다타
인간 보기/편집마우스 보기/편집

LPA로도5 알려진 리소포인산 수용체 5는 인간에게 LPAR5 유전자에 의해 암호화된 단백질이다.[5][6][7][8][9]LPA는5 지질 신호 분자 리소포인산산(LPA)[10]을 결합하는 G단백질 결합 수용체다.

참고 항목

참조

  1. ^ a b c GRCh38: 앙상블 릴리스 89: ENSG00000184574 - 앙상블, 2017년 5월
  2. ^ a b c GRCm38: 앙상블 릴리스 89: ENSMUSG000067714 - 앙상블, 2017년 5월
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ White, Kenneth E.; Evans, Wayne E.; O'Riordan, Jeffery L.H.; Speer, Marcy C.; Econs, Michael J.; Lorenz-Depiereux, Bettina; Grabowski, Monika; Meitinger, Thomas; Strom, Tim M. (Dec 2000). "Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23". Nat Genet. 26 (3): 345–8. doi:10.1038/81664. PMID 11062477. S2CID 38870810.
  6. ^ Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene. 275 (1): 83–91. doi:10.1016/S0378-1119(01)00651-5. PMID 11574155.
  7. ^ Lee CW, Rivera R, Gardell S, Dubin AE, Chun J (Aug 2006). "GPR92 as a new G12/13- and Gq-coupled lysophosphatidic acid receptor that increases cAMP, LPA5". J Biol Chem. 281 (33): 23589–97. doi:10.1074/jbc.M603670200. PMID 16774927.
  8. ^ Kotarsky K, Boketoft A, Bristulf J, Nilsson NE, Norberg A, Hansson S, Owman C, Sillard R, Leeb-Lundberg LM, Olde B (Jul 2006). "Lysophosphatidic acid binds to and activates GPR92, a G protein-coupled receptor highly expressed in gastrointestinal lymphocytes". J Pharmacol Exp Ther. 318 (2): 619–28. doi:10.1124/jpet.105.098848. PMID 16651401. S2CID 5989815.
  9. ^ "Entrez Gene: GPR92 G protein-coupled receptor 92".
  10. ^ Choi JW, Herr DR, Noguchi K, Yung YC, Lee CW, Mutoh T, Lin ME, Teo ST, Park KE, Mosley AN, Chun J (January 2010). "LPA Receptors: Subtypes and Biological Actions". Annual Review of Pharmacology and Toxicology. 50 (1): 157–186. doi:10.1146/annurev.pharmtox.010909.105753. PMID 20055701.

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